Gene Information

Name : SAS0027 (SAS0027)
Accession : YP_042160.1
Strain : Staphylococcus aureus MSSA476
Genome accession: NC_002953
Putative virulence/resistance : Unknown
Product : type I restriction enzyme methylase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 38891 - 40678 bp
Length : 1788 bp
Strand : -
Note : Similar to Escherichia coli type I restriction enzyme EcoR124II M protein HsdM or Hsm SWALL:T1M1_ECOLI (SWALL:P10484) (520 aa) fasta scores: E(): 8.6e-16, 23.81% id in 504 aa, and to Caulobacter crescentus type I restriction-modification system, M subunit

DNA sequence :
ATGAGCGAATTTAAAAGACATCAACAAACATCAATTAATGTTCAAAAACAAGCAAACCTTATTTGGAATGTTGCAGACAT
TTTAAGGGGTTTATACAAACCTCATGAATATGGAAAGGTTATCTTACCAATGACTGTCATTAAACGTCTTCACGATACAT
TACTAAAAACGCGAGACAAAGTTCTTAAGACTGCAGAAAATACCCAATCAATAAATGACGTAATGCGAGAACGCCTTTTG
AAGAACGCTTCAGGGTATTCATTTTATAATACAAGCTTATATACTTTTGAAACATTACTCGCAGACCCAGCAAATATTGA
ATCAAACTTTAGAGCTTATCTCAATGGTTTCTCTGAAAACATGCAAGATATTCTCAATAACTTTAAGTTCGACGTTGAAA
TTACGACAATGGCAGATAATGACGTGCTATTTTATGTGATTCAAGAATTTAACAAAGCAGATGCATATCTAGGTCCAGAC
AAAATGACAAGCACAGATATGGGATACGTGTTCGAGGAACTTGTACGAAAATTTTCGGAAAGCTATAACGAGGAAGCAGG
TGCACACTTCACGAGTCGAGATATCATTTATCTCATGACTGATTTATTGCTTATCGAAGATAAAGATACTTTGTTTAAAG
AACATGTTTTCAAAACTGTCTACGACCAAACAATGGGAACTTCCCAAATGCTCTCAGCAATGACAGAACGTATTCACGAT
ATGAATGATACTGCCGAAGTAGCTACCTTTGGTCAAGAGCTAAATCCTGAAACTTATGCGATTTCGAAAGCAGATACAAT
GATTCGTGGGGGAGATCCTGAAAACATGGCGCTTGGAAGTACATTAACGAGCGACCGGTTTGAAGGATTTACATTTGATT
ACTGTATCTCCAACCCACCATTTGGTGTCGATTGGAAAAAGGACCAAAAAGCAGTAAAAGCAGAACATGAACTTGGTGAA
CTCGGTCGCTTTGGTGTTGGATTGCCTCGAGTTAGTGATGGACAGTTGTTATTTCAACTCAATGGTATTTCAAAATTAAA
GGAAACAGGACGCATGGCAATTATTCACAACGGTTCTGCCTTATTCTCTGGAAACCCAGGTGCTGGCGAGAGTTTAATTC
GTCAGTACGTAATTGAGAATGATTGGTTAGAGGGCATAATCCAACTTCCTAACGACTTATTCTACAATACAGGAATTTCA
ACGTATATTTGGATTATTACTAAAGATAAATCTCCAGAACGTCAAGGGAAAGTACAACTCGTTGATGCGTCCAATATGTA
TGAAAAACGTCGTAAGAATATTGGTGAAAAACGCGTAGATATTTCTGAAGCATGTCGAGAAATGATTGTGCAAGCTTATG
GAGAATTTAATGATAAAGAATACTATCTAGGAGATGGAACTGTAGAGTCAAAAATACTTAAGAATGAATCATTTGGTTTT
ACTCGAGTGACTATTGAACGACCGCAACGAGACGAAAACGGAGATATCGTTTATAAAAAGAATGGAAGCAAGAGTGTAGA
CACGAACCTTAGAGATACAGAAGATATTCCCTTAACAGAAGATATTAATGAATATTTTGAACGTGAAATATTACCATTTA
ATCAAGATGCATGGATGGATCGTAAAAAAGATAAGATAGGGTATGAAATTCCATTTACTAGATTGTTTTACAAATATACA
CCACCAGAACCATCTGAAGTTATTTCAGAACGTATTAAACAACTCGAAGAGTCTATTATTAAAAACTTCCAAGCATTATC
TGGAAAGGAAGTGGATACAAATGAGTAG

Protein sequence :
MSEFKRHQQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRERLL
KNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPD
KMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHD
MNDTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHELGE
LGRFGVGLPRVSDGQLLFQLNGISKLKETGRMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGIS
TYIWIITKDKSPERQGKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGF
TRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYT
PPEPSEVISERIKQLEESIIKNFQALSGKEVDTNE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0027 YP_042160.1 type I restriction enzyme methylase Not tested SCC476 Protein 0.0 100