Gene Information

Name : SAS2335 (SAS2335)
Accession : YP_044447.1
Strain : Staphylococcus aureus MSSA476
Genome accession: NC_002953
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 2499257 - 2500192 bp
Length : 936 bp
Strand : -
Note : ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGAAAATTGCAATTGCTGGATCGGGTGCATTAGGTAGTGGCTTTGGTGCCAAACTATTTCAAGCAGGATATGATGTCAC
ACTTATTGACGGATATACATCTCATGTTGAAGCGGTTAAGCAACATGGATTAAATATAACGATTAATGGAGAGGCATTCG
AGTTAAACATTCCGATGTATCATTTTAATGATCAACCGGACGAAAGCATTTACGATGTTGTCTTTCTATTTCCAAAGTCT
ATGCAATTAAAAGAAGTGATGGAAGATATGAAGCCACATATTGATAATGAAACGATCGTCGTATGTACGATGAATGGTCT
GAAGCATGAAGAAGTCATTGCGCAGTATGTTGCTCAATCACAAATTGTCAGAGGTGTTACGACTTGGACGGCAGGTCTTG
AAAGCCCTGGACACAGTCATTTACTTGGTAGTGGACCAGTTGAAATAGGTGAACTAGTGGATGAAGGTAAAGAAAATGTT
ATAAAAGTTGCTGATTTACTTAACGAAGCGGAATTGAATGGTGTCATTAGTAAAGATTTATACCAATCGATTTGGAAAAA
GATTTGTGTTAATGGTACGGCAAATGCATTAAGCACAGTGTTGGAGTGTAATATGGCATCGCTGAATGAAAGTAGTTATG
CGAAGTGTTTGATTTATAAATTAACGCAAGAAATAGTGCATGTAGCGACGATTGATAATGTTCATTTAAATGTTGATGAA
GTATTTGAATATTTAGTTGATTTAAATGAAAAAGTTGGTGCGCATTATCCATCCATGTATCAAGATTTAATTGTTAATAA
TAGAAAAACTGAAATTGATTATATTAATGACGCAGTTGCAACATTGGGTAAACAACGTCATATTGAAGCGCCAGTCAATC
GCTTTATTACTGATTTAATTCATACTAAAGAAAGTCAGCGACACGCACAGGATTAA

Protein sequence :
MKIAIAGSGALGSGFGAKLFQAGYDVTLIDGYTSHVEAVKQHGLNITINGEAFELNIPMYHFNDQPDESIYDVVFLFPKS
MQLKEVMEDMKPHIDNETIVVCTMNGLKHEEVIAQYVAQSQIVRGVTTWTAGLESPGHSHLLGSGPVEIGELVDEGKENV
IKVADLLNEAELNGVISKDLYQSIWKKICVNGTANALSTVLECNMASLNESSYAKCLIYKLTQEIVHVATIDNVHLNVDE
VFEYLVDLNEKVGAHYPSMYQDLIVNNRKTEIDYINDAVATLGKQRHIEAPVNRFITDLIHTKESQRHAQD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 2e-48 42
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 2e-48 42