Gene Information

Name : SAS2311 (SAS2311)
Accession : YP_044423.1
Strain : Staphylococcus aureus MSSA476
Genome accession: NC_002953
Putative virulence/resistance : Virulence
Product : gamma-hemolysin component C precursor
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2472070 - 2473017 bp
Length : 948 bp
Strand : +
Note : Ortholog of S. aureus MRSA252 (BX571856) SAR2510

DNA sequence :
ATGCTTAAAAATAAAATATTAGCCACAACTTTATCTGTGAGCTTACTTGCCCCTCTTGCCAATCCGTTATTAGAAAATGC
TAAAGCTGCCAACGATACTGAAGAGATCGGTAAAGGAAGCGATATAGAAATTATCAAAAGGACAGAAGATAAAACAAGTA
ATAAATGGGGCGTGACTCAAAATATTCAATTTGATTTTGTGAAGGATAAAAAATATAACAAAGATGCTTTGATATTAAAG
ATGCAAGGATTCATTAGCTCTAGAACAACATATTACAACTATAAAAAAACTAATCATGTTAAAGCTATGCGATGGCCATT
CCAATATAATATTGGTTTAAAAACAAATGATAAATATGTTTCTTTAATTAATTATTTACCTAAAAATAAAATTGAATCTA
CAAACGTGAGTCAGACATTAGGATACAATATCGGTGGTAATTTCCAATCAGCCCCATCACTCGGTGGTAATGGATCATTT
AACTATTCTAAATCGATTAGCTATACACAACAAAATTATGTAAGTGAAGTAGAACAACAAAACTCAAAAAGTGTTTTATG
GGGCGTCAAAGCGAATTCATTCGCCACTGAATCAGGTCAAAAATCAGCATTTGATAGCGATTTATTTGTAGGCTACAAAC
CTCATAGTAAAGATCCTAGAGATTATTTCGTTCCAGACAGTGAGTTACCACCTCTTGTACAAAGTGGATTTAACCCTTCA
TTTATCGCCACAGTATCTCATGAAAAAGGTTCAAGCGATACAAGCGAATTTGAAATTACTTACGGAAGAAACATGGATGT
CACTCATGCCATTAAAAGATCAACGCATTATGGCAACAGTTATTTAGACGGACATAGAGTCCATAATGCATTTGTAAATA
GAAACTATACTGTGAAATACGAGGTCAATTGGAAGACTCATGAAATCAAGGTGAAAGGACAGAATTGA

Protein sequence :
MLKNKILATTLSVSLLAPLANPLLENAKAANDTEEIGKGSDIEIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILK
MQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSF
NYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPS
FIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKYEVNWKTHEIKVKGQN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor Virulence ¥ÕSa2 Protein 4e-113 77
lukS-PV YP_494079.1 Panton-Valentine leukocidin, LukS-PV Virulence ¥ÕSa2 Protein 4e-113 77
lukE YP_001332753.1 leukocidin LukE precursor Virulence vSa¥â Protein 4e-88 68
lukE YP_494460.1 leukotoxin LukE Virulence vSa¥â Protein 4e-88 68
lukE YP_186708.1 leukotoxin LukE Virulence vSa¥â Protein 4e-88 68
lukE NP_646585.1 leukotoxin LukE Virulence vSa¥â Protein 4e-88 68
lukE NP_372344.1 leukotoxin S-subunit Virulence vSa¥â Protein 4e-88 68
lukE NP_374927.1 leukotoxin LukE Virulence vSa¥â Protein 4e-88 68
SAKOR_01768 YP_008491956.1 Leukocidin S subunit lukE Virulence vSa¥â Protein 4e-88 68
SAOV_1909 YP_005737354.1 leukocidin chain lukM precursor Virulence ¥ÕSa3 Protein 7e-86 65

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SAS2311 YP_044423.1 gamma-hemolysin component C precursor VFG1274 Protein 5e-134 99
SAS2311 YP_044423.1 gamma-hemolysin component C precursor VFG1277 Protein 2e-113 77
SAS2311 YP_044423.1 gamma-hemolysin component C precursor VFG1273 Protein 6e-88 68