Gene Information

Name : SAS2103 (SAS2103)
Accession : YP_044213.1
Strain : Staphylococcus aureus MSSA476
Genome accession: NC_002953
Putative virulence/resistance : Virulence
Product : hyaluronate lyase precursor 2
Function : -
COG functional category : -
COG ID : -
EC number : 4.2.2.1
Position : 2273510 - 2275957 bp
Length : 2448 bp
Strand : +
Note : Ortholog of S. aureus MRSA252 (BX571856) SAR2292

DNA sequence :
ATGACATATAGAATAAAGAAATGGCAAAAATTATCCACCATTACGTTATTAATGGCTGGTGTGATTACTTTGAATGGTGG
TGAATTCAGAAGTATTGATAAATATCAAATCGCTGTGGCTGATACGAATGTTCAAACGCCAGATTATGAAAAGTTGAGGA
ACACATGGCTGGACGTTAACTATGGTTATGATAAGTATGATGAGAAGAATGACGCAATGAAGAAGAAGTTTGAGGCTACG
GAGAATGAGGCAAAGAAATTACTTAGTGAGATGAAAACTGAAAGTGATAGGAAATACTTGTGGGAAAACTCAAAAGATTT
AGATACGAAGTCTGCGGATATGACTCGTACCTATCGTAATATTGAGAAAATCGCAGAAGCGATGAAGCATAAAGATACTA
AGTTAAAAATAGATGAAAACAAGAAGAAAGTGAAAGATGCCCTTGAGTGGCTGCATAAAAATGCATATGGAAAAGAACCA
GATAAAAAAGTTGCTGATTTGACCTCAAACTTTAAAAATAAAACTTCTAGAAATACCAATTTAAATTGGTGGGATTATGA
AATTGGAACACCTAGAGCATTAACAAATACCCTTATATTGCTGAATGATCAATTTTCAAATGACGAAAAGAAAAAATACA
CTGCCCCTATCAAAACTTTCGCCCCAGAAAGTGACAAAATATTATCATCAGTAGGACAACCTGAACAAGCTAAAGGGGGA
AATTTAGTAGACATTGCTAAAGTAAAACTTTTAGAAAGTATTATCGAAGAAGATAAAGATATAACTAAAAATTCAATAGA
TGCATTTAATAAAGTCTTCACTTACGTTCAAAGTAATGCAACTGGTAAAGAACGTAATGGATTCTATAAAGACGGCTCTT
ATATTGATCATCAAGACGTCCCATACACTGGTGCTTATGGCGTTGTACTCTTAGAGGGGATTTCTCAAATGATGCCGATG
ATAAAAGAAACACCTTTTAATGATAAAACCCAAAATGATACAACCTTAAAGTCATGGATTGACGACGGATTTATGCCACT
CATTTATAAAGGTGAAATGATGGATTTATCAAGAGGTAGAGCTATCAGTCGTGAAAATGAAACGAGTCATACAGCGTCAG
CGACTGTAATGAAATCATTGTTGAGATTGAGTGATGCCATGGATGATTCAACAAAAGCTAAGTATAAGCAAATCGTTAAA
ACTTCTGTTAAATCTGATTCAAGTTACGGCCAAAATGATACATTAAGCTCTTATTCGGATATAAGCAAAATGAAGTCTTT
AATGGAAGACAGCACTATTTCTACTAACGGTTTAACACAACAACTTAAAATATATAATGACATGGATCGTGTCACCTATC
ACAATAAAGACTTAGACTTTGCATTTGGTTTAAGTATGACGTCGAAAAACGTCGCACGTTACGAAAGTATCAACGGAGAG
AACTTAAAAGGTTGGCACACTGGTGCTGGAATGTCTTATTTATACAATAGCGATGTGAAACACTACCGTGATAACTTCTG
GGCGACAGCTGATATGAAACGTTTAGCAGGTACAACAACTTTAGAAAATGAAGAACCTAAAGGTACGGATGTTAAAAAGT
CGAGTAAAACTTTTGTAGGCGGAACAAAATTCGATGACCAACATGCTAGTATCGGAATGGATTTTGAAAATCAGGACAAA
ACTTTAACTGCCAAAAAATCATATTTCATATTAAACGATAAAATTGTCTTCTTAGGAACTGGCATTAAAAGTACTGATTC
ATCAAAGAATCCAGTTACAACGATTGAAAATCGCAAAGCGAATGGGTATACGTTATATACAGACGATAAACAAACAACCG
CTTCCGATAATCAGGGAACCAATTCCGTCTTTTTAGAGTCAACCAATAAACCTAAAAACAATATAGGCTATCATTTTTTA
AACGAATCGAAAATAACTGTAAAAAAAGAAAGTCATACTGGTAAGTGGAGTGATATAAATAAAAGTCAAAAGCAAGACAG
TAAAACTAATCAATATTATGAAGTAACTCAAAAGCATTCTAATACAGATAGTAAATATGCATATGTGTTGTATCCAGGCT
TATCTAAAGATGACTTTAATACAAAAAAAGATAAAGTAACTGTCGTTAAACAAGATGATGACTTCCACGTTGTGAAAGAT
AATGAATCGGTTTGGGCTGGTGTTAATTACAGCGATAGCACTCAAACTTTTATCATTAACAACACTAAAGTCGAAGTTAA
AGCAAAAGGTATGTTTATACTTAAAAAGAAAGATGATAAAACTTATGAATGTAGCTTCTATAATCCCGAATCTACAAATA
CCGCTTCAGATATTGAATCTAAAATTTCAATGACTGGATACTCTATTACAAACAAAAATACGTCGACTTCTAATGAATCC
GGCGTGCGCTTTGAATTACAACAAACATTAAATAAAGATGATAATTAA

Protein sequence :
MTYRIKKWQKLSTITLLMAGVITLNGGEFRSIDKYQIAVADTNVQTPDYEKLRNTWLDVNYGYDKYDEKNDAMKKKFEAT
ENEAKKLLSEMKTESDRKYLWENSKDLDTKSADMTRTYRNIEKIAEAMKHKDTKLKIDENKKKVKDALEWLHKNAYGKEP
DKKVADLTSNFKNKTSRNTNLNWWDYEIGTPRALTNTLILLNDQFSNDEKKKYTAPIKTFAPESDKILSSVGQPEQAKGG
NLVDIAKVKLLESIIEEDKDITKNSIDAFNKVFTYVQSNATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPM
IKETPFNDKTQNDTTLKSWIDDGFMPLIYKGEMMDLSRGRAISRENETSHTASATVMKSLLRLSDAMDDSTKAKYKQIVK
TSVKSDSSYGQNDTLSSYSDISKMKSLMEDSTISTNGLTQQLKIYNDMDRVTYHNKDLDFAFGLSMTSKNVARYESINGE
NLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLENEEPKGTDVKKSSKTFVGGTKFDDQHASIGMDFENQDK
TLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANGYTLYTDDKQTTASDNQGTNSVFLESTNKPKNNIGYHFL
NESKITVKKESHTGKWSDINKSQKQDSKTNQYYEVTQKHSNTDSKYAYVLYPGLSKDDFNTKKDKVTVVKQDDDFHVVKD
NESVWAGVNYSDSTQTFIINNTKVEVKAKGMFILKKKDDKTYECSFYNPESTNTASDIESKISMTGYSITNKNTSTSNES
GVRFELQQTLNKDDN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hysA1 YP_041274.1 hyaluronate lyase precursor 1 Virulence vSa¥â Protein 0.0 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SAS2103 YP_044213.1 hyaluronate lyase precursor 2 VFG1315 Protein 0.0 100