Gene Information

Name : hlgB (SAS1748)
Accession : YP_043864.1
Strain : Staphylococcus aureus MSSA476
Genome accession: NC_002953
Putative virulence/resistance : Virulence
Product : gamma-hemolysin component B precursor
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1897813 - 1898796 bp
Length : 984 bp
Strand : -
Note : Similar to Staphylococcus aureus gamma-hemolysin component B precursor HlgB SWALL:HLGB_STAAN (SWALL:Q07226) (325 aa) fasta scores: E(): 9.7e-96, 75.92% id in 324 aa

DNA sequence :
ATGAAAATGAAAAAATTAGTCAAATCATCAGTTGCTTCATCAATTGCACTGCTTTTGCTATCGAATACAGTTGATGCAGC
TCAACATATCACACCTGTAAGCGAGAAAAAAGTAGATGACAAAATCACTTTATACAAAACAACAGCAACATCTGATAATG
ATAAATTGAATATTTCTCAAATTTTAACGTTTAATTTCATTAAGGATAAAAGTTATGACAAAGATACGTTAGTACTTAAG
GCAGCCGGAAACATTAATTCAGGTTATAAAAAGCCTAATCCAAAAGATTACAATTACTCACAGTTTTATTGGGGCGGTAA
GTATAATGTTTCGGTTAGTTCAGAATCAAATGATGCTGTAAATGTTGTTGACTATGCACCTAAAAATCAAAATGAAGAAT
TCCAAGTTCAACAAACATTAGGTTATTCTTATGGCGGAGATATTAATATATCTAATGGCTTATCAGGTGGATTAAATGGA
TCAAAATCATTTTCAGAAACGATAAATTATAAACAAGAAAGTTACAGAACTACGATTGATAGAAAAACAAATCATAAATC
AATTGGCTGGGGTGTTGAGGCGCACAAAATTATGAATAATGGTTGGGGACCATATGGTAGAGATAGTTATGACCCAACAT
ATGGTAATGAACTGTTTTTAGGTGGTAGACAAAGTAGTTCAAATGCTGGTCAAAATTTCTTGCCAACACATCAAATGCCT
TTATTGGCGCGTGGTAACTTTAACCCAGAATTTATAAGCGTACTTTCTCATAAACAAAATGATACAAAAAAATCTAAAAT
CAAAGTAACTTACCAAAGAGAAATGGATAGATATACTAATCAATGGAATCGACTACACTGGGTTGGTAATAACTACAAAA
ATCAAAATACAGTAACGTTTACATCTACTTATGAAGTTGACTGGCAAAACCATACTGTTAAATTAATCGGTACGGATTCT
AAAGAAACTAATCCTGGAGTATAA

Protein sequence :
MKMKKLVKSSVASSIALLLLSNTVDAAQHITPVSEKKVDDKITLYKTTATSDNDKLNISQILTFNFIKDKSYDKDTLVLK
AAGNINSGYKKPNPKDYNYSQFYWGGKYNVSVSSESNDAVNVVDYAPKNQNEEFQVQQTLGYSYGGDINISNGLSGGLNG
SKSFSETINYKQESYRTTIDRKTNHKSIGWGVEAHKIMNNGWGPYGRDSYDPTYGNELFLGGRQSSSNAGQNFLPTHQMP
LLARGNFNPEFISVLSHKQNDTKKSKIKVTYQREMDRYTNQWNRLHWVGNNYKNQNTVTFTSTYEVDWQNHTVKLIGTDS
KETNPGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lukD YP_494459.1 leukotoxin LukD Virulence vSa¥â Protein 8e-131 100
lukD YP_186707.1 leukotoxin LukD Virulence vSa¥â Protein 8e-131 100
lukD NP_646584.1 leukotoxin Virulence vSa¥â Protein 8e-131 100
lukD YP_001332752.1 leukocidin LukD precursor Virulence vSa¥â Protein 8e-131 100
SAKOR_01767 YP_008491955.1 Leukocidin F subunit lukD Virulence vSa¥â Protein 1e-130 99
lukD NP_372343.2 leukotoxin F-subunit Virulence vSa¥â Protein 1e-130 99
lukD NP_374926.1 leukotoxin, LukD Virulence vSa¥â Protein 1e-130 99
SAOV_1908 YP_005737353.1 Panton-Valentine leukocidin LukF-PV chain precursor Virulence ¥ÕSa3 Protein 4e-109 85
lukF-PV YP_494078.1 Panton-Valentine leukocidin, LukF-PV Virulence ¥ÕSa2 Protein 3e-106 83
lukF NP_646195.1 Panton-Valentine leukocidin chain F precursor Virulence ¥ÕSa2 Protein 3e-106 83

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hlgB YP_043864.1 gamma-hemolysin component B precursor VFG1276 Protein 1e-106 83
hlgB YP_043864.1 gamma-hemolysin component B precursor VFG1275 Protein 1e-102 76