Gene Information

Name : SAS1745 (SAS1745)
Accession : YP_043861.1
Strain : Staphylococcus aureus MSSA476
Genome accession: NC_002953
Putative virulence/resistance : Virulence
Product : lantibiotic biosynthesis protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1893490 - 1896483 bp
Length : 2994 bp
Strand : -
Note : Similar to Staphylococcus epidermidis epidermin biosynthesis protein EpiB SWALL:EPIB_STAEP (SWALL:P30195) (986 aa) fasta scores: E(): 3.1e-127, 45.08% id in 996 aa, and to Bacillus subtilis subtilin biosynthesis protein SpaB or SpaD or spaE SWALL:SPAB_BAC

DNA sequence :
ATGAACACTATTTACGAACCGTCAAGTATTTGTATGATTAGAACACCTTTATTATCAGTTGAATTTTTCAATTTATTTTT
AAATACTGAACAAATTAAATATAGCGACTTACAATTAAATGCTCAGATGAAAGAATCAATCCTAACAACAACATTTAACT
TATATTGTACTTTACAAGAAATAAATTTTGATGGCGATAACAAGAAGGTTAGAGATGCTAAAGAAAGTTTATTAAAATAT
TTAATTAGAATGTCAACACGTCCAACTCCATTTGGATTATTAAGTGGTATTAATTTGGGGCATTTTGTAAATGAACCAAC
ACGTCTTAAAGTTGGAAATAGTATTCAAAAATATGTGAAAGTCGATGGCGAATGGTTGTATAAACTGGTTAGTTATATTG
AGAGTATTGATGAATATTATCAAAATTTGAAAGTTATTTGGAATAGTAAAGCACATATTATCAATGATCGAATATATTTA
AATGAACAAAGTGCTATTTATTTAAACAACAATAAAGATACATCTTTTTCCATTAAAAATAGCGAATTACTCGTATTCAT
CAAAACCACTGTGACGAATAATAATATTACTTTTTCAAATTTAGCTGAAAAGATAAATCAAGAATTTGAAATTAATGATA
TTACTAAAGTGAAAGTATATATCCATAATCTTGTCTCAAAGGAAATTATATATTCAACAATCAGACCACCGTTATCATAT
AGCGATAATTTAAATTATATTTTAAATAAACTTTCTTTACATAATGATGATTTTGTGAAAAAAATTAGAGAAATCCAGAA
ATTGATATTAGCTTATGAAAAAACTGAAATTGGATTTGGCGAGGAATTATATAAAGACATTATTCATCATATGAAGGCAC
TATTCAAATGTAAAAACTATCTTCAAATTGATACCAAAATTGACATGATTAACAATTATTTACATCAAGATATAGCAACA
AATATATCTGAAGCAGCGTACTTATTGTGGCTTTTATCAAGAAATAATATTGGATTCACAGATTTGAAAGTTCTTCACAA
CCGTTTTATTGAAAAGTATGGATTTGAACAACTCGTGAATATTAAAGATTTGATTTCAGATATAACAGGTTTCGGGACAA
CAATTTTTCAAGAAGAAGAAACCGATGGAAATAATATTGTAATGCTTAAGCAAAAATTTTTACATGCCTTGAGAAATAAC
GATGAGATAGTCATAAATGAAAAAGATGTAGAGTCATTGATTAACGATAATGAAATCAATCATTATCATGCGCCAATGAG
TGCAGATGTTTATGCTGAACTTTATTTAGGACGTTTTTACAATCAGTACAATGAGCTCATTGTTATTAGTCCTTTAACGG
CGTCTTTTAATGCTGGCGCTACATTTGGGCGATTTCATCATTTAATTGATACTGAAACTTTAGCAAAATTAGAACATGAA
AAAGGACATTATTATCAGAAGATGATATGTGATGACAATGTAGAAATGATTTCTATAAATAACATACCGAAATATCCGAG
AAATCATAATGTATTAACTAATCATGACTCATACGAATATTCATTGAATTTAGGAAGTAGTAATAGTTATTCAAAGTATG
AGCTTACCTTAGATGATATTTATGTTGGTGCTACCTTTAACAAATTATATTTATATTCTAGCCAACTAAATAAAAGGGTA
CTATTTGAATCAAACAATATGTATAACTTTTTAAAAGAATGTAATTTATATCGATTGTTACGAGAAATTTCAATGGAATC
TGTGAAATGCATTGAATCTATGAATGATGTGAGTATTGATTCATTTAGTTATTCACCACGAATCAGATATAAAAATGTCA
TTCTTAAACCAGCATATTGGAAAATTAACGAGATGGTATTACCTTTACCTAAAAATGAAGAATGGGATCAACAATTTTTG
AAATATCAAGAACAATTCAATATACCTAATATCGTGAATTTAGTTTATGGAGATAACAAGCTTCTACTAAATTTATCATT
AGCTAATCATAGATATTTATTGATGAAAGAATATAAGAAGCATAAACGTGTACGTTTAGTAGAATCATTTTTACCTCAAT
CAAAGAATGATCATGTGTATGAAATTGTTACACCAATTTATAAAAAATCATCTTATCGAGGACCCGAAATCGAAATTCCA
AAATATAAAAATACAGATATTGAATATGACAAAGACTGGTTTGCATTACATATTCATATCGATAAGCCATCGCAAGATAC
ATTTATCATCGACAATTTGTATCCATTTGTAAAACATCTTAAAGATAAGGGAGATATAGAAAAATATTTTTTAATGCGTT
ATATCAAACAAGGTGACATTTTAAAGTTGAGGTTATTCAGGAATGACGAAAATTACGCAGAAATATACAGCATCTTGAAG
AATTGGTTACCACATGTTCGACAAACGACAGAAGTTTCAGATTATGAATTTGTATCATACGAGCCAGAATTTTTTAGATA
TGGTGGAAAGAACACGATTAATGAAATAGAAGCCTTCTTTGAATATGACACGAATTTAGCTGTCAATATTATTGAAAATG
ATTTTAAGTTTGATCGACCATATATTGTTGCTATTTCAATAATGTATTTATTTGAGATGTTTTCAATTTCTAATGAAGAG
CGTATGGAAATTGTTAATAACTATGTACCTACATCATTTAAAAGTAAAGATATTAGACCTTTTAAAAATGAACTTGTAAC
TATATGTAATCCTGCTAATAATTTTGAATATATGGCTAAACACTATAGTGGTATTTATCGAATTTTAAAAGATGGCAACC
AAATTTTGAGCAAATTAAATGAAGGGCTTAAAAAAACTTTAACTACTAAAAGGTCAAGGATTATTGGCAGCTTAATTCAT
ATGCGCTGCAATCGAATATTTGGCATTGATAAGGATCAAGAAACATTTGTTTTATCTATTGTAAAAGAAATTGTTAAAAC
TCAAAAGCATTGGTGTGGTGACAAAAATGATTGA

Protein sequence :
MNTIYEPSSICMIRTPLLSVEFFNLFLNTEQIKYSDLQLNAQMKESILTTTFNLYCTLQEINFDGDNKKVRDAKESLLKY
LIRMSTRPTPFGLLSGINLGHFVNEPTRLKVGNSIQKYVKVDGEWLYKLVSYIESIDEYYQNLKVIWNSKAHIINDRIYL
NEQSAIYLNNNKDTSFSIKNSELLVFIKTTVTNNNITFSNLAEKINQEFEINDITKVKVYIHNLVSKEIIYSTIRPPLSY
SDNLNYILNKLSLHNDDFVKKIREIQKLILAYEKTEIGFGEELYKDIIHHMKALFKCKNYLQIDTKIDMINNYLHQDIAT
NISEAAYLLWLLSRNNIGFTDLKVLHNRFIEKYGFEQLVNIKDLISDITGFGTTIFQEEETDGNNIVMLKQKFLHALRNN
DEIVINEKDVESLINDNEINHYHAPMSADVYAELYLGRFYNQYNELIVISPLTASFNAGATFGRFHHLIDTETLAKLEHE
KGHYYQKMICDDNVEMISINNIPKYPRNHNVLTNHDSYEYSLNLGSSNSYSKYELTLDDIYVGATFNKLYLYSSQLNKRV
LFESNNMYNFLKECNLYRLLREISMESVKCIESMNDVSIDSFSYSPRIRYKNVILKPAYWKINEMVLPLPKNEEWDQQFL
KYQEQFNIPNIVNLVYGDNKLLLNLSLANHRYLLMKEYKKHKRVRLVESFLPQSKNDHVYEIVTPIYKKSSYRGPEIEIP
KYKNTDIEYDKDWFALHIHIDKPSQDTFIIDNLYPFVKHLKDKGDIEKYFLMRYIKQGDILKLRLFRNDENYAEIYSILK
NWLPHVRQTTEVSDYEFVSYEPEFFRYGGKNTINEIEAFFEYDTNLAVNIIENDFKFDRPYIVAISIMYLFEMFSISNEE
RMEIVNNYVPTSFKSKDIRPFKNELVTICNPANNFEYMAKHYSGIYRILKDGNQILSKLNEGLKKTLTTKRSRIIGSLIH
MRCNRIFGIDKDQETFVLSIVKEIVKTQKHWCGDKND

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
epiB YP_186704.1 epidermin biosynthesis protein EpiB Virulence vSa¥â Protein 0.0 99
bsaB YP_001332749.1 lantibiotic biosynthesis protein Not tested vSa¥â Protein 0.0 99
epiB YP_494457.1 lantibiotic epidermin biosynthesis protein EpiB Not tested vSa¥â Protein 0.0 99
bsaB NP_646581.1 hypothetical protein Not tested vSa¥â Protein 0.0 99