Gene Information

Name : SAS1744 (SAS1744)
Accession : YP_043860.1
Strain : Staphylococcus aureus MSSA476
Genome accession: NC_002953
Putative virulence/resistance : Resistance
Product : lantibiotic biosynthesis protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG4403
EC number : -
Position : 1892253 - 1893497 bp
Length : 1245 bp
Strand : -
Note : Similar to Staphylococcus epidermidis epidermin biosynthesis protein EpiC SWALL:EPIC_STAEP (SWALL:P30196) (455 aa) fasta scores: E(): 1.8e-70, 46.71% id in 411 aa, and to Streptococcus mutans MutC protein SWALL:Q9RPL7 (EMBL:AF154675) (424 aa) fasta scores

DNA sequence :
ATGATTGATATGAATCTAATATTGAAGAAGAAGTTTCAAGAGATTTCAGAAGTAGATGATTTCATTTCAAAAGCATCTAC
TGAAACCGATTATTTTGAACCTTCAACTTTATCACATGGTATACCAGGTATCATTTTGTTTTTAGATGCTTATCAAAAAG
TTTTCGATATTAATACTGAGCAAATTGTGCATAAGTACATCATGAAATTAGCACCATATTTACAGAGTGGTCAATATAAC
AATTCTTTGTTTGGTGGACTTTCAGGTATTGCATTTTCAATGGATTTAGCATCGCAAAATGGCAAAAATTATCAAAATAT
TTTAAATAATATTGATGGTCACATTGTAAATGAAATAGAAAATAAATTTGATCAAATATTACAAGAACCATTAAATCCAT
TAAATTATGATACTGTCAGTGGATTAGCTGGGATAGGGAGATATTTGCTAAATAGAGTAGATGAGAATGAATTTAATGTT
AAAGCATTAAAAAGCATATTAGTATACTTTAAAGATATTCAATATTCTAAAAATAGCTGGGTAGTCCCACAAGAAAGTCA
ATTTTTAGAGTCTGATAAAAATTATTTTACTGAAGGTAATATCAATCTTGGCCTTGCACATGGAGTGCTAGGACCGATGT
CTTTATTTGCATTATGCGTGATTAAAGGAATTACGATTGAAAATCATCAGCACATATTAAAAGACATGTACAAATTTATC
ATGGACGAAAAATTTTGTAACCACGAAAGATGGTTGCAGCGTTACGATTTAATTTCTGAACGTAATCATTTCAATTTTAT
TCGGAATGGTTGGTGTTATGGCAATACGGGTGTAATGACGACGTTGTTTTTAATCGGCCAAGCATTACAAGATGATGAAA
TAATTAAAATGTCTAAAAAAGTGATGCTACAAGTAGTAAATGATAAAGATGAAAATTTAATAAGTCCAACTATTTGTCAT
GGATTGTCATCACAAATATTAATGTTAACAATTATGAATTTGAATTTTGAATTAAATGAAGTGTCTGATTATATCACTGT
ATTAATAAATAAACTGATTTCTCATTATAAGGAAGATTATCTGGTGAATTTTATAGACATTAATGAAAATAAGCAAGATG
TATTTAAAAGTAGGAAAGTTGGCCTTTTAGAAGGTGAATTAGGGGTCTATCTAACATTGATGACACTGAAAAATACAAAA
ATTCTCAATGAAAAAAATTGGACCAATGCGTTTTTAATTAGCTGA

Protein sequence :
MIDMNLILKKKFQEISEVDDFISKASTETDYFEPSTLSHGIPGIILFLDAYQKVFDINTEQIVHKYIMKLAPYLQSGQYN
NSLFGGLSGIAFSMDLASQNGKNYQNILNNIDGHIVNEIENKFDQILQEPLNPLNYDTVSGLAGIGRYLLNRVDENEFNV
KALKSILVYFKDIQYSKNSWVVPQESQFLESDKNYFTEGNINLGLAHGVLGPMSLFALCVIKGITIENHQHILKDMYKFI
MDEKFCNHERWLQRYDLISERNHFNFIRNGWCYGNTGVMTTLFLIGQALQDDEIIKMSKKVMLQVVNDKDENLISPTICH
GLSSQILMLTIMNLNFELNEVSDYITVLINKLISHYKEDYLVNFIDINENKQDVFKSRKVGLLEGELGVYLTLMTLKNTK
ILNEKNWTNAFLIS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
bsaC NP_646580.1 hypothetical protein Not tested vSa¥â Protein 0.0 100
bsaC YP_001332748.1 lantibiotic biosynthesis protein Not tested vSa¥â Protein 0.0 100
epiC YP_494456.1 lantibiotic epidermin biosynthesis protein EpiC Not tested vSa¥â Protein 0.0 100