Gene Information

Name : SAS1742 (SAS1742)
Accession : YP_043858.1
Strain : Staphylococcus aureus MSSA476
Genome accession: NC_002953
Putative virulence/resistance : Virulence
Product : lantibiotic leader peptide processing serine protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG1404
EC number : -
Position : 1890336 - 1891709 bp
Length : 1374 bp
Strand : -
Note : Similar to Staphylococcus epidermidis epidermin leader peptide processing serine protease EpiP precursor epiP SWALL:EPIP_STAEP (SWALL:P30199) (461 aa) fasta scores: E(): 3.1e-77, 49.24% id in 461 aa, and to an internal region of Lactococcus lactis nisin l

DNA sequence :
ATGAAAATCATAAAGCGCGCTATTATTAGTTTAATAATATTGAGTCTTTTAATATCTATTACAATGAGTAATGCATCAGC
GTCAGAAGAACTATATTACAGTGTTGAATACAAAAATACAGCAACATTTAACAAGTTAGTTAAAAAGAAGTCCTTAAACG
TTGTCTATAATATACCGGAATTACATGTGGCACAGATTAAAATGACGAAAATGCATGCTAATGCTTTAGCAAACTATAAA
AATGATATTAAATATATCAATGCCACATGTTCAACTTGTATTACTAGCGAGAAAACAATAGACAGAACATCAAATGAGTC
ATTATTTTCAAGACAATGGGATATGAATAAAATAACCAATAATGGTGCATCGTATGATGATTTGCCAAAACATGCTAACA
CCAAAATAGCAATCATAGATACAGGTGTGATGAAAAACCATGACGATTTGAAAAATAATTTCTCGACTGATTCTAAAAAT
TTAGTACCTTTAAACGGTTTTAGAGGTACTGAACCGGAGGAAACAGGTGATGTTCACGATGTCAATGATAGGAAAGGACA
TGGCACGATGGTGTCGGGTCAAACGAGTGCTAATGGTAAGTTAATAGGTGTTGCACCGAATAACAAATTTACAATGTATC
GCGTGTTTGGTAGTAAAAAAACAGAACTGCTTTGGGTATCAAAAGCGATTGTTCAAGCTGCAAATGATGGAAATCAAGTC
ATTAATATTAGTGTTGGTAGTTATATTATTTTGGACAAAAATGACCATCAAACATTTAGAAAAGATGAAAAAGTAGAATA
CGATGCGTTACAGAAAGCAATCAATTACGCCAAGAAGAAAAAATCTATCGTTGTTGCTGCAGCTGGTAATGATGGTATTG
ATGTCAATGACAAACAGAAACTAAAATTACAGCGTGAATATCAAGGTAATGGCGAAGTGAAAGATGTTCCTGCATCTATG
GACAATGTCGTTACAGTAGGATCTACAGATCAAAAGAGTAATCTATCTGAGTTTTCCAATTTTGGTATGAATTATACAGA
TATTGCTGCGCCCGGAGGATCATTTGCTTATTTAAATCAATTCGGTGTGGATAAATGGATGAATGAAGGGTATATGCATA
AGGAGAACATTTTAACTACTGCCAATAACGGAAGATATATTTATCAAGCTGGAACTTCATTAGCCACACCTAAAGTTTCG
GGAGCACTAGCTTTAATCATTGATAAATATCATCTTGAAAAACATCCAGATAAAGCGATTGAATTGTTATATCAGCATGG
GACATCTAAGAATAATAAACCATTTAGTAGATATGGGCATGGTGAGCTTGATGTGTATAAAGCATTAAATGTAGCAAATC
AAAAAGCAAGTTAA

Protein sequence :
MKIIKRAIISLIILSLLISITMSNASASEELYYSVEYKNTATFNKLVKKKSLNVVYNIPELHVAQIKMTKMHANALANYK
NDIKYINATCSTCITSEKTIDRTSNESLFSRQWDMNKITNNGASYDDLPKHANTKIAIIDTGVMKNHDDLKNNFSTDSKN
LVPLNGFRGTEPEETGDVHDVNDRKGHGTMVSGQTSANGKLIGVAPNNKFTMYRVFGSKKTELLWVSKAIVQAANDGNQV
INISVGSYIILDKNDHQTFRKDEKVEYDALQKAINYAKKKKSIVVAAAGNDGIDVNDKQKLKLQREYQGNGEVKDVPASM
DNVVTVGSTDQKSNLSEFSNFGMNYTDIAAPGGSFAYLNQFGVDKWMNEGYMHKENILTTANNGRYIYQAGTSLATPKVS
GALALIIDKYHLEKHPDKAIELLYQHGTSKNNKPFSRYGHGELDVYKALNVANQKAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
epiP YP_494454.1 lantibiotic epidermin leader peptide processing serine protease EpiP Not tested vSa¥â Protein 0.0 100
epiP YP_186702.1 epidermin leader peptide processing serine protease EpiP Virulence vSa¥â Protein 0.0 100
bsaP NP_646578.1 hypothetical protein Not tested vSa¥â Protein 0.0 100
bsaP YP_001332746.1 lantibiotic leader peptide processing serine protease Not tested vSa¥â Protein 0.0 100