Gene Information

Name : SAS1741 (SAS1741)
Accession : YP_043857.1
Strain : Staphylococcus aureus MSSA476
Genome accession: NC_002953
Putative virulence/resistance : Virulence
Product : lantibiotic transport ATP-binding protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1131
EC number : -
Position : 1889621 - 1890313 bp
Length : 693 bp
Strand : -
Note : Similar to Streptococcus pyogenes lantibiotic transport ATP-binding protein SrtF or spy1085 SWALL:SRTF_STRPY (SWALL:Q9FDU7) (229 aa) fasta scores: E(): 1.3e-32, 48.85% id in 219 aa, and to Staphylococcus epidermidis ABC transporter subunit EpiF SWALL:Q540

DNA sequence :
ATGGCAAAATTAGTTACTGAAAACATTTCGAAACGGTTTAAAAATCAAGATGTATTAAAGCATATTAATATCACTTTAGA
AAATAACGAAGTTTATGGATTACTTGGTATTAATGGAGCCGGTAAAACGACACTTATGAAAATTATATGTGGCATACTTC
AACAAGATTCAGGGGAAATTAAATTAGATAATAGACCAATGACACGAAATGATTTGCACAAAGTTGGTTCGCTTATTGAA
ACACCTGCGACATATAATCATTTAAGTGCACAAGATAATTTGAAAATTGTGTGTTTAAATGAAAGCGTTGATTTCAGCGA
AATTAATAGTGTTTTAAGCTTAGTCAATTTAAATGTCGATAAAAAGAAAAAGGTTAAGGACTTTTCTTTAGGTATGAAAC
AAAGACTTGGAATTGCAATGGCATTAATTAAAAAGCCAGAAATTTTAGTATTAGACGAACCATCTAATGGTTTAGACCCA
TATGGAATCCAAGAACTTAGAGAACTTCTAAAATTATTAACAGAACAAGGTACTAGTATTATTATTTCAAGTCACATTTT
ATCTGAAATCCAAGTTTTAGCAGATCATATCGGTATTATTCATGAGGGTGAGCTAAAATATCAGCAAAGAAATAACAAAG
ATGAAAACTTAGAAGAGATATTCTTCAAAATAACGAAAGGTGATTACAAATGA

Protein sequence :
MAKLVTENISKRFKNQDVLKHINITLENNEVYGLLGINGAGKTTLMKIICGILQQDSGEIKLDNRPMTRNDLHKVGSLIE
TPATYNHLSAQDNLKIVCLNESVDFSEINSVLSLVNLNVDKKKKVKDFSLGMKQRLGIAMALIKKPEILVLDEPSNGLDP
YGIQELRELLKLLTEQGTSIIISSHILSEIQVLADHIGIIHEGELKYQQRNNKDENLEEIFFKITKGDYK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
epiF YP_186701.1 epidermin immunity protein F Virulence vSa¥â Protein 3e-86 100
bsaF NP_646577.1 hypothetical protein Not tested vSa¥â Protein 3e-86 100
epiF YP_494453.1 lantibiotic epidermin immunity protein F Not tested vSa¥â Protein 3e-86 100
bsaF YP_001332745.1 lantibiotic immunity protein F Not tested vSa¥â Protein 2e-86 100
SPN23F_09830 YP_002510959.1 lantibiotic transport ATP-binding protein Not tested PPI-1 Protein 7e-21 45
cdd4 CAA63569.1 - Not tested PaLoc Protein 2e-24 45
CD241_0087 YP_005124356.1 ABC transporter ATP-binding protein Not tested Not named Protein 1e-25 41
DIP0090 NP_938487.1 ABC transporter ATP-binding protein Not tested Not named Protein 6e-26 41
SH2304 YP_254219.1 ABC-type multidrug transport system, ATPase Not tested ¥ðSh1 Protein 2e-22 41