Gene Information

Name : hemC (SAS1599)
Accession : YP_043718.1
Strain : Staphylococcus aureus MSSA476
Genome accession: NC_002953
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1720702 - 1721628 bp
Length : 927 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGCGTAAATTAGTCGTTGGCTCCAGAAGAAGTAAATTAGCTTTAACACAAAGCCAGCAATTTATTGATAAATTAAAAGC
TGTCGAGCCAAATCTAGAAATTGAAATTAAAGAAATTGTCACGAAAGGCGATCGTATAGTAGATAAGCAATTGTCTAAAG
TCGGAGGCAAAGGCTTATTTGTTAAAGAAATACAACATGAACTTTTTGAAAAAAATATCGATATGGCAATACACTCGCTT
AAAGATGTACCAAGTGTAATTCCGGAAGGTTTAACATTAGGTTGTATCCCTGATAGAGAATTACCTTTTGATGCGTATAT
TTCTAAAACACATACACCACTATCCCAATTGCCAGAAGGCAGTATTATTGGTACTAGTTCATTACGTCGTGGTGCACAAA
TATTATCTAAGTATCCTAATTTAGAGATTAAATGGATTAGAGGTAATATAGATACACGATTAGAAAAGTTACAAACTGAA
GATTATGATGCGATTATTTTAGCTGCAGCTGGTTTAAGAAGAATGGGCTGGTCAGATGATATTGTAACATCTTATCTTGA
TAGAGATACATTGTTACCTGCAATCGGACAAGGTGCTTTAGGGATAGAATGTCGTAGTGACGATGAAGAACTATTAACAT
TATTAAGCAAAGTACATAATGATGAGGTTGCAAAATGTGTGACTGCTGAACGAACGTTTTTAGCAGAAATGGATGGTAGT
TGTCAGGTGCCAATCGCAGGATATGCTACAATCTCAGATCAAAAAGAAATCGAATTTACAGGTTTAATTATGACCCCAGA
TGGTAAAGAACGATTTGAATATACAATGAACGGAACAGATCCGGTTGAGTTAGGCAAAACAGTGAGTAACAAATTAAAAG
AGCAAGGTGCTTATGAAATTATAAAACGCTTAAATGAACAACATTAA

Protein sequence : 
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLFVKEIQHELFEKNIDMAIHSL
KDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEGSIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTE
DYDAIILAAAGLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEIIKRLNEQH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 8e-64 47
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 8e-64 47