Gene Information

Name : nrdF (SAR0786)
Accession : YP_040213.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 824083 - 825054 bp
Length : 972 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGATAGCTGTTAATTGGAACACACAAGAAGATATGACGAATATGTTTTGGAGACAAAATATATCTCAAATGTGGGTTGA
AACAGAATTTAAAGTATCAAAAGACATTGCAAGTTGGAAGACTTTGTCAGAAGCTGAACAAGACACATTTAAAAAAGCAT
TAGCTGGTTTAACAGGCTTAGATACACATCAAGCAGATGATGGTATGCCTTTAGTCATGCTACATACGACTGACTTAAGA
AAAAAAGCAGTTTATTCATTTATGGCGATGATGGAGCAAATACACGCGAAAAGTTATTCGCATATTTTCACAACGCTATT
ACCATCTAGTGAAACAAACTATTTATTAGATGAATGGGTTTTAGAAGAGCCACATTTAAAATATAAATCAGATAAAATTG
TTGCTAATTACCACAAACTTTGGGGTAAAGAAGCTTCCATATATGACCAATATATGGCCAGAGTTACGAGTGTATTTTTA
GAAACATTCTTATTCTTCTCTGGTTTCTATTATCCGCTATATTTAGCTGGTCAAGGAAAAATGACGACATCAGGCGAAAT
CATTCGTAAAATTCTTTTAGATGAATCTATTCATGGTGTGTTTACTGGTTTAGATGCGCAGCATTTACGAAATGAACTAT
CTGAAAGCGAGAAGCAAAAAGCTGACCAAGAAATGTATAAATTGCTAAATGACTTGTATTTAAATGAAGAGTCATACACA
AAAATGTTATACGATGATCTTGGAATCACTGAAGATGTGTTAAACTATGTTAAATATAATGGAAATAAAGCACTTTCAAA
TTTAGGTTTTGAACCTTATTTTGAGGAACGTGAATTTAACCCAATTATTGAGAATGCCTTAGATACAACAACTAAAAACC
ATGACTTCTTCTCTGTAAAAGGTGATGGTTATGTATTAGCATTAAATGTAGAAGCATTACAAGATGATGACTTTGTATTT
GACAACAAATAA

Protein sequence :
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLR
KKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFL
ETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYT
KMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVF
DNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nrdF YP_189075.1 ribonucleotide-diphosphate reductase subunit beta Not tested ¥ÕSP¥â Protein 1e-82 55