Gene Information

Name : rir1 (SAR0785)
Accession : YP_040212.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 821858 - 823963 bp
Length : 2106 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGAAAACCATGGAAGAGAAAAAGTACAATCATATTGAATTAAATAATGAGGTCACTAAACGAAGAGAAGATGGATTCTT
TAGTTTAGAAAAAGACCAAGAAGCTTTAGTAGCTTATTTAGAAGAAGTAAAAGATAAAACAATCTTCTTCGACACTGAAA
TCGAGCGTTTACGTTATTTAGTAGACAACGATTTTTATTTCAATGTGTTTGATATTTATAGTGAAGCGGATCTAATTGAA
ATCACTGATTATGCAAAATCAATCCCGTTTAATTTTGCAAGTTATATGTCAGCTAGTAAGTTTTTCAAAGATTACGCTTT
GAAAACAAATGATAAAAGTCAATATTTAGAAGACTATAATCAACACGTTGCAATTGTTGCTTTATACCTAGCAAATGGTA
ATAAAGCACAAGCTAAACAATTTATTTCTGCTATGGTTGAACAAAGATATCAACCAGCGACACCAACATTTTTAAACGCC
GGCCGTGCGCGTCGTGGTGAGCTAGTGTCATGTTTCTTATTAGAAGTGGATGACAGCTTAAATTCAATTAACTTTATTGA
TTCAACTGCAAAACAATTAAGTAAAATTGGTGGCGGCGTAGCAATTAACTTATCTAAATTGCGTGCACGTGGTGAAGCGA
TTAAAGGAATTAAAGGCGTAGCGAAAGGTGTTTTACCTATTGCTAAGTCACTTGAAGGTGGCTTTAGCTATGCAGATCAA
CTAGGTCAACGCCCTGGTGCTGGTGCTGTGTACTTAAATATCTTCCATTATGATGTAGAAGAATTTTTAGATACTAAAAA
AGTAAATGCGGATGAAGATTTACGTTTATCTACAATATCAACTGGTTTAATTGTTCCATCTAAATTCTTCGATTTAGCTA
AAGAAGGTAAAGACTTTTATATGTTTGCACCTCATACAGTTAAAGAAGAATACGGTGTTACATTAGACGATATTGATTTA
GAAAAATATTATGATGATATGGTTGCAAATCCAAATGTTGAGAAAAAGAAAAAGAATGCACGTGAAATGTTGAATTTAAT
TGCGCAAACACAATTACAATCAGGCTATCCATATTTAATGTTTAAAGATAATGCTAATAGAGTTCATCCGAATTCAAATA
TTGGACAAATTAAGATGAGTAACTTATGTACTGAAATTTTCCAATTACAAGAAACTTCAATTATTAACGACTATGGTATT
GAAGACGAAATTAAACGTGATATTTCTTGTAACTTAGGTTCATTAAACATTGTAAATGTAATGGAAAGCGGAAAATTCAG
AGATTCAGTTCACTCTGGTATGGACGCATTAACTGTTGTAAGTGATGTAGCAAATATTCAAAATGCTCCAGGAGTTAGAA
AAGCTAATAGTGAATTACATTCAGTTGGTCTTGGTGTGATGAATTTACATGGTTACTTAGCAAAAAATAAAATTGGTTAT
GAGTCAGAAGAAGCAAAAGATTTTGCAAATATCTTCTTTATGATGATGAATTTCTACTCAATCGAACGTTCAATGGAAAT
CGCTAAAGAACGTGGTATCAAATATCAAGACTTTGAAAAGTCTGATTATGCTAATGGCAAATATTTCGAGTTCTATACAA
CTCAAGAATTTGAACCTCAATTCGAAAAAGTACGTGAATTATTTGACGGTATGGCTATTCCTACTTCTGAGGATTGGAAG
AAACTACAACAAGATGTTGAACAATATGGTTTATATCATGCATATAGATTAGCTATTGCTCCAACACAAAGTATTTCTTA
TGTTCAAAATGCTACAAGTTCTGTAATGCCAATAGTAGATCAAATTGAACGTCGTACTTATGGTAATGCGGAAACATTTT
ACCCTATGCCATTCTTATCGCCTCAAACAATGTGGTACTACAAATCTGCATTCAATACTGATCAGATGAAATTAATCGAT
TTAATTGCGACAATTCAAACGCATATTGACCAAGGTATCTCAACGATACTTTATGTTAATTCTGAAATTTCTACACGTGA
GTTAGCAAGATTATATGTATATGCGCACTATAAAGGATTAAAATCACTTTACTATACTAGAAATAAATTATTAAGTGTAG
AAGAATGTACAAGTTGTTCTATCTAA

Protein sequence :
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIE
ITDYAKSIPFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNA
GRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQ
LGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDL
EKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGI
EDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGY
ESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWK
KLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLID
LIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 2e-134 43