Gene Information

Name : SAR0069 (SAR0069)
Accession : YP_039537.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : sensor kinase
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2205
EC number : -
Position : 74067 - 76787 bp
Length : 2721 bp
Strand : -
Note : Two-component regulatory system family, sensor kinase. Similar to Clostridium acetobutylicum histidine kinase sensor protein KdpD SW:KDPD_CLOAB (P94608) (900 aa) fasta scores: E(): 1.2e-75, 29.538% id in 887 aa, and to Rhizobium loti two-component sensor

DNA sequence :
ATGGATAATATGTTGTATATTAATTATGATGTGATTAAGAGGGGGTGCCTCATGGAAAGTACATATAAAAAAAGAGGGAA
ACTTACCATTTATTTAGGCTATAGCCCAGGGGTAGGTAAAACGTATGAAATGTTATCAAATGGTATTGATCAGTATCAAG
AAGGTGCAGATATTAAAATTGGTTATATCGAACCCCATCAACGCCCTGAAACCAATGCACTGGTTCAACAATTGCCTGAA
ATTTCGACCTCCAGCCGTAAATTTGGCAGCCACACCTTTCACTATATAGATGTCTCTAAAATCATAGAAGCTAATCCAGA
TGTGGTCTTAATTGATGAACTAGCACATACAAACATTTCAAAAGAGCGCCATTTAAAACGTTATAAGGATATAGAAGAAA
TTCTATCGCATGGTATCGATGTCTGGACAACACTCAACATCCAACATATCGAGAGTCTAAGCGGACAAATTGCGTTAATG
ACAGGTATTCAAGTTACAGAACGTGTGCCCGACCAATTCATTACGTCAGCAGATGCCTTTGAAGTTGTGGATATTTCACC
AAATATGTTGATTCAGCGCCTTAAAGCAGGAAAAGTATATAAAAAAGAACGCTTAGAAACAGCCTTTTCTAATTTCTTTA
CGTATGAAAATCTGACAGAGCTGCGTGAACTTACACTCAGAACTGTCGCAGATATTATGAGTCAAAAAGGACAACAATAT
AAAACTAAACATACCGACATTACACCGCATATTGCGGTAGCTATCAGCGGCAGTATTTATAACGAACGGGTCATACGAGA
AGCAAGACGTGCTGCCTATAAAGAACATGCTAAATTCACAGCTGTGTATATTGATGTCTTTGAGACACCGTCAGAAAGCA
GAAAACAAGATCATTATGTCCATAAAAATCTAATGCTCGCCAAAGCGTTAGGTGCAGAAATCAAAGTGTTGTATGCACAA
GATATTGCGAAAGCGTTAACCGATTGGTGTGATCTCGCTTTTGTGACGAAGCTAGTCCTTGGACAGTCAGAACAGCCACG
TTGGAAAGATTACTTTAAACAGTCACTCATTGAACAAATTAATCACGTACCACACCATTTCAAGTTAGAAATTGTACCGA
TTCATTATATTCATTCAGACAAACCTACAAATACACCTAAGCAAGCTCAAAAATCCTCTCGTTTAACTGTAGAGATTATG
AAGATGCTTGTAATTCAAACGATCTGTGTCTTGCTCGGTATATGGGTTTACAACTTAGATAAAAGCGAATCCAGTGCCAT
TATCTTGCTGATGTTCTTTATCGGTATTATCGTGCTTTCTATTTGGACCCAATCCTATTTAATCGGATTCTTTGCGTCTA
TCTTAAATGTGTTTGTTTTTAATTATTTCTTTACGGTGCCAAGATTCACTTTAGAAATGTATCGCTTTGAATATCCGATT
ACGTTTGCGACCAGTATTTTTGCTAGTATCTTTACGAGTGCCATCTTAAAGAATTTAAAACATCAGCATTCCTTAACAGA
ACGGCAGTTATATCGGACCAATATTATGCTGCAATTTAACCAGTCCATTAAAGAATCTTATTCAATTGAACGCTTATTAA
ATATTGCTGGTGATCAGATTCATCAGCTACTCAATCAGGATGTCACGGTATTCTTAATTCAAAGTAAGAAAGTCGCTGCT
TCCAACTCATTTGGAAACAGAAGCATTTCAAGCTCAGATAAGACACATGATGCTGAGACATTGAGCTGGGTCATTGAAAA
TGAAAGCCGTGCCGGTAAATTAACCGATACCTTTCCTGGCAGTAAATTTTTGTGTATTCCCATTGGCACAAATCCAGTCA
AAGGTGTGATTTCTATCCGCTTCACCGACGAAACTTACATCGACACCTATGACAATTCAATATTAGACTCTATGTTGAAC
GATATTACCCTGGCAATAGAGAATGTGGATCTATTAAAACAAACCAGACAATCCATATTGAAAGCTGAACGAGAAGCCAC
ACGTTCAAACTTCTTGCATTCAATTTCACATGATATTAGAACACCACTGACTTCCATTATGGGCAACTTAGATATGCTGA
AATACCATAACGAGCATTTAAACGATCAACAACAAGCAGAACTCTTAACTGCTTCTTATGGCGAAGCACAATATCTGCAT
ACCTTAGTCACAAATATTTTATCTTTGACTAAGTTAGAAAGCTCTGACATTCAAATACAACGCACCCCTTATTTAGTAGA
AGAACTTCTAGAAGAATTTGAAGAAGGCCTCATACGCAGACACCAAGCAAATCATGTCATTATTGAAAATGAGGATGACG
CTTCACTCATTAATATCGACAGTAAATTAATACTGCAAGTGCTATTCAACCTTATCGATAATGCTTTAAAGCATGCAGAA
TCACATTCTGAAATAAAACTGCACGTTCAACATGAAACAAACAAAATAAAATTCGAAATGATAGATTGCGGAAAAGGTAT
TCCAGAAGAAGAACGTCAATTGATTTTTAATCCCTATTATTCAGGAGACAACTTTAAAGACAATAAAAAAGATAGTTTGG
GATTAGGGCTCTATTTAGTACAACTCATCTTGAAACAACACAACAGTGAATTAGAATATCAACCGAATACACCACAAGGC
AGTATTTTTTATTTTTATTTGACTGTTAATCCAATTGAAATGGAGGGAGCCATGGATGAAAACAACATTATTGGTCGTTG
A

Protein sequence :
MDNMLYINYDVIKRGCLMESTYKKRGKLTIYLGYSPGVGKTYEMLSNGIDQYQEGADIKIGYIEPHQRPETNALVQQLPE
ISTSSRKFGSHTFHYIDVSKIIEANPDVVLIDELAHTNISKERHLKRYKDIEEILSHGIDVWTTLNIQHIESLSGQIALM
TGIQVTERVPDQFITSADAFEVVDISPNMLIQRLKAGKVYKKERLETAFSNFFTYENLTELRELTLRTVADIMSQKGQQY
KTKHTDITPHIAVAISGSIYNERVIREARRAAYKEHAKFTAVYIDVFETPSESRKQDHYVHKNLMLAKALGAEIKVLYAQ
DIAKALTDWCDLAFVTKLVLGQSEQPRWKDYFKQSLIEQINHVPHHFKLEIVPIHYIHSDKPTNTPKQAQKSSRLTVEIM
KMLVIQTICVLLGIWVYNLDKSESSAIILLMFFIGIIVLSIWTQSYLIGFFASILNVFVFNYFFTVPRFTLEMYRFEYPI
TFATSIFASIFTSAILKNLKHQHSLTERQLYRTNIMLQFNQSIKESYSIERLLNIAGDQIHQLLNQDVTVFLIQSKKVAA
SNSFGNRSISSSDKTHDAETLSWVIENESRAGKLTDTFPGSKFLCIPIGTNPVKGVISIRFTDETYIDTYDNSILDSMLN
DITLAIENVDLLKQTRQSILKAEREATRSNFLHSISHDIRTPLTSIMGNLDMLKYHNEHLNDQQQAELLTASYGEAQYLH
TLVTNILSLTKLESSDIQIQRTPYLVEELLEEFEEGLIRRHQANHVIIENEDDASLINIDSKLILQVLFNLIDNALKHAE
SHSEIKLHVQHETNKIKFEMIDCGKGIPEEERQLIFNPYYSGDNFKDNKKDSLGLGLYLVQLILKQHNSELEYQPNTPQG
SIFYFYLTVNPIEMEGAMDENNIIGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0069 YP_039537.1 sensor kinase Not tested Type-II SCCmec Protein 0.0 100
kdpD YP_190032.1 sensor histidine kinase KdpD Not tested Type-II SCCmec Protein 0.0 100
kdpD NP_370595.1 sensor protein KdpD Not tested Type-II SCCmec Protein 0.0 99
kdpD NP_373307.1 hypothetical protein Not tested Type-II SCCmec Protein 0.0 99
SH0032 YP_251947.1 hypothetical protein Not tested SCCmec Protein 0.0 99