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Name : cadA (SAR0723) Accession : YP_040151.1 Strain : Staphylococcus aureus MRSA252 Genome accession: NC_002952 Putative virulence/resistance : Resistance Product : cadmium-transporting ATPase Function : - COG functional category : P : Inorganic ion transport and metabolism COG ID : COG2217 EC number : 3.6.3.3 Position : 760452 - 762632 bp Length : 2181 bp Strand : - Note : Similar to Staphylococcus aureus plasmid pI258 probable cadmium-transporting ATPase CadA SW:CADA_STAAU (P20021) (727 aa) fasta scores: E(): 0, 91.586% id in 725 aa, and to Bacillus firmus probable cadmium-transporting ATPase CadA SW:CADA_BACFI (P30336) (7 DNA sequence : TTGGATAGTTCAGCAAAAACATTAACAGAAGATAAACAGGTTTACCGTGTGGAGGGTTTCTCGTGTGCGAATTGTGCTGG GAAGTTTGAAAAAAATGTAAAACAACTAGCTGGAGTTCAGGATGCAAAAGTGAACTTTGGCGCTTCCAAAATTGATGTAT ATGGAAATGCATCGGTTCAAGAGCTTGAAAAAGCAGGTGCTTTCGAGAATCTTAAGGTATTTCCCGAAAAACTAGCGAAT TCATCGATGCAAGCGGTCAAAGAAGACACTAAGGCTCCTAAAGAAGAGAAAATACCGTTTTATAAAAAACACAGCACATT GCTGTTTGCCACATTACTGATTGCTTTTGGTTACCTTTCTCACTTTGTAAATGGAGAAGATAACCTTGTAACTTCCATGT TATTTGTAGGTTCGATTGTAATTGGCGGATATTCACTATTTAAAGTTGGTTTTCAAAATTTGATACGCTTTGATTTCGAC ATGAAAACCCTGATGACCGTAGCAGTTATTGGAGCTGCCATCATTGGTGAATGGGCAGAGGCATCCATTGTTGTCGTTCT CTTTGCAATCAGTGAAGCACTTGAACGTTTTTCTATGGATAGAGCAAGACAGTCCATTCGTTCATTGATGGATATTGCCC CAAAAGAAGCACTTGTTATGCGGAATGGTCAGGAAATAATGATCCATGTGGACGATATTGCCGTGGGTGATATTATGATC GTCAAACCAGGGGAGAAAATTGCCATGGATGGGATCATTATAAATGGTGTGTCGGCTGTCAACCAGGCTGCTATAACAGG AGAATCTGTCCCTGTTGCCAAAACGGTAGATGATGAAGTATTTGCAGGTACGCTTAACGAAGAGGGACTACTTGAAGTAA AAATCACCAAATACGTAGAGGATACAACTATCTCCAAGATTATTCATCTGGTTGAGGAAGCACAAGGGGAGCGCGCTCCA GCGCAAGCATTCGTAGATAAATTTGCGAAATATTATACGCCGATCATTATGGTTATTGCGGCGCTCGTTGCAGTCGTTCC ACCTTTATTCTTTGGTGGAAGTTGGGATACTTGGGTTTATCAAGGATTAGCGGTACTTGTAGTTGGATGTCCGTGTGCAT TAGTTATTTCTACTCCAATCTCGATTGTCTCGGCAATTGGAAATGCAGCTAAAAAAGGTGTGTTGATTAAAGGCGGTGTC TATCTAGAGGAATTAGGAGCCATTAAGGCAATCGCATTTGATAAAACAGGAACACTGACAAAAGGTGTACCAGTGGTAAC AGATTTTAAAGTGTTAAATGATCAAGTGGAAGAAAAAGAGCTGTTTTCCATTATTACAGCTTTAGAATATCGATCACAAC ATCCACTTGCTTCAGCAATAATGAAGAAAGCAGAGCAAGATAATATTACTTATTCCGATGTTAGAGTGGAGGACTTCACT TCTATTACAGGTCGGGGCATTCAAGGGAATATAGATGGAACAACCTATTACATTGGCAGTCCAAGGCTTTTTAAAGAATT AAATGTTTCCGATTTTAGCCTTGAGTTTGAAAATAAAGTGAAAGTTTTACAAAACCAAGGGAAAACGGCCATGATTATTG GAACGGACCAAACAATCCTCGGCGTGATTGCTGTAGCAGATGAGGTCCGCGAAACAAGTAAAAATGTGATTCAAAAACTT CATCAGTTAGGAATCAAGCAAACAATTATGCTGACAGGTGATAATCAAGGTACCGCAGAAGCAATCGGTGCTCATGTAGG CGTTTCTGATATTCAGTCCGAATTGATGCCACAGGATAAGTTGGACTATATTAAAAAAATGAAAGCCGAGCATGGTAATG TAGCTATGATTGGCGATGGCGTCAATGATGCTCCTGCACTTGCTGCATCCACTGTTGGCATTGCAATGGGCGGTGCTGGA ACAGATACTGCCATCGAGACAGCTGATATTGCATTAATGGGAGATGATTTAAGTAAGCTTCCATTTGCAGTAAGACTTAG CAGGAAAACGCTAAATATCATCAAAGCGAACATCACGTTTGCCATCGGAATTAAGATAATTGCCTTACTATTGGTTATTC CAGGCTGGCTAACCCTTTGGATTGCGATTCTTTCCGATATGGGAGCCACTATTTTGGTAGCATTAAATAGTTTGCGACTG ATGAGAGTGAAGGATAAATAG Protein sequence : MDSSAKTLTEDKQVYRVEGFSCANCAGKFEKNVKQLAGVQDAKVNFGASKIDVYGNASVQELEKAGAFENLKVFPEKLAN SSMQAVKEDTKAPKEEKIPFYKKHSTLLFATLLIAFGYLSHFVNGEDNLVTSMLFVGSIVIGGYSLFKVGFQNLIRFDFD MKTLMTVAVIGAAIIGEWAEASIVVVLFAISEALERFSMDRARQSIRSLMDIAPKEALVMRNGQEIMIHVDDIAVGDIMI VKPGEKIAMDGIIINGVSAVNQAAITGESVPVAKTVDDEVFAGTLNEEGLLEVKITKYVEDTTISKIIHLVEEAQGERAP AQAFVDKFAKYYTPIIMVIAALVAVVPPLFFGGSWDTWVYQGLAVLVVGCPCALVISTPISIVSAIGNAAKKGVLIKGGV YLEELGAIKAIAFDKTGTLTKGVPVVTDFKVLNDQVEEKELFSIITALEYRSQHPLASAIMKKAEQDNITYSDVRVEDFT SITGRGIQGNIDGTTYYIGSPRLFKELNVSDFSLEFENKVKVLQNQGKTAMIIGTDQTILGVIAVADEVRETSKNVIQKL HQLGIKQTIMLTGDNQGTAEAIGAHVGVSDIQSELMPQDKLDYIKKMKAEHGNVAMIGDGVNDAPALAASTVGIAMGGAG TDTAIETADIALMGDDLSKLPFAVRLSRKTLNIIKANITFAIGIKIIALLLVIPGWLTLWIAILSDMGATILVALNSLRL MRVKDK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | BAB47609.1 | cadmium resistance protein B | Not tested | Type-III SCCmec | Protein | 0.0 | 99 |
| cadA | BAC57487.1 | Probable cadmium-transporting ATPase (Cadmium efflux ATPase) | Not tested | Type-IIIinv SCCmec | Protein | 0.0 | 99 |
| SE0075 | NP_763630.1 | cadmium resistance protein B | Not tested | SCCpbp4 | Protein | 0.0 | 82 |
| ORF C97 | AAN62190.1 | putative metal-transporting P-type ATPase | Not tested | PAGI-2(C) | Protein | 5e-124 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| cadA | YP_040151.1 | cadmium-transporting ATPase | BAC0298 | Protein | 5e-122 | 48 |
| cadA | YP_040151.1 | cadmium-transporting ATPase | BAC0092 | Protein | 2e-98 | 43 |
