Gene Information

Name : arsC (SAR0692)
Accession : YP_040129.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Resistance
Product : arsenate reductase
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0394
EC number : -
Position : 737706 - 738101 bp
Length : 396 bp
Strand : +
Note : catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates

DNA sequence : 
ATGGATAAGAAAACAATTTATTTTATATGTACAGGAAACTCTTGTCGTAGCCAAATGGCTGAAGGTTGGGGAAAGGAAAT
ATTGGGTGAAGGTTGGAATGTCTATTCTGCTGGTATTGAAACACATGGTGTTAATCCTAAAGCAATAGAAGCTATGAAAG
AAGTAGATATTGATATATCAAACCATACGTCAGACTTGATTGATAATGATATTTTAAAACAATCAGATTTGGTCGTAACG
TTATGTAGTGATGCAGACAATAATTGTCCTATTTTACCACCAAACGTTAAAAAAGAGCATTGGGGTTTTGATGATCCAGC
AGGTAAAGAATGGTCAGAATTCCAACGTGTTAGAGACGAGATTAAATTAGCTATAGAAAAGTTTAAATTGAGATAA

Protein sequence : 
MDKKTIYFICTGNSCRSQMAEGWGKEILGEGWNVYSAGIETHGVNPKAIEAMKEVDIDISNHTSDLIDNDILKQSDLVVT
LCSDADNNCPILPPNVKKEHWGFDDPAGKEWSEFQRVRDEIKLAIEKFKLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsC YP_005754064.1 arsenate reductase Not tested Type-XI SCCmec Protein 4e-50 93
arsC YP_252016.1 arsenate reductase Not tested SCCmec Protein 2e-51 92
arsC YP_252023.1 arsenate reductase Not tested SCCmec Protein 4e-52 89

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsC YP_040129.1 arsenate reductase BAC0032 Protein 4e-57 100
arsC YP_040129.1 arsenate reductase BAC0580 Protein 4e-55 95
arsC YP_040129.1 arsenate reductase BAC0581 Protein 2e-40 65
arsC YP_040129.1 arsenate reductase BAC0586 Protein 3e-15 41