Gene Information

Name : arsB1 (SAR0691)
Accession : YP_040128.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Resistance
Product : arsenical pump membrane protein 1
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 736399 - 737688 bp
Length : 1290 bp
Strand : +
Note : Highly similar to Staphylococcus aureus arsenical pump membrane protein ArsB SW:ARSB_STAAU (P30329) (429 aa) fasta scores: E(): 2e-142, 99.301% id in 429 aa, and to Staphylococcus xylosus arsenical pump membrane protein ArsB SW:ARSB_STAXY (Q01255) (429 aa

DNA sequence :
ATGACTATTTTAGCAATTGTAATTTTTCTTTTAACTTTAACCTTTGTGATTTGGCAACCAAAAGGTTTAGATATTGGTAT
TACAGCTTTAATTGGAGCTGTTGTTGCTATCATTACAGGAGTCGTAAGTCTTTCTGATGTATTAGAAGTAACAGGTATTG
TTTGGAATGCAACTTTAACTTTTGTGGCTGTTATTCTTATTTCATTAATATTAGATGAAATTGGTTTTTTTGAATGGTCT
GCGATACATATGGTCAAGGCTTCAAACGGTAATGGCTTAAAAATGTTTGTTTTTATTATGTTACTTGGAGCAATTGTAGC
AGCATTTTTCGCAAATGATGGTGCAGCTTTAATCTTAACGCCTATTGTATTAGCGATGGTAAGGAATCTAGGATTTAATC
AAAAAGTGATTTCCCCCTTTATTATTGCCAGTGGTTTTATTGCTGATACTACATCACTTCCCTTAATTGTAAGTAACTTA
GTTAATATCGTTTCTGCAGATTACTTCGATATTGGATTTATTGAATATTTTAGCCGAATGATCATTCCTAATATATTCTC
TCTGATTGCTAGTATTCTCGTTTTATGGTTATATTTCAGAAAATCCATACCTAAAACGTTCGATACAGAAAATCTATCAG
ATCCTAAAAGTGCAATTAAAGATTCTAAGTTATTTAAGCTTTCATGGATAGTATTAGCAGTACTACTCGTTGGATATCTT
GTTAGCGAGTTTATCCAAATTCCTGTATCAATTATTGCTGGTATTATTGCTTTTATCTTTGTAATATTAGCTCGTAAATC
TAAAGCAGTTCATACAAAACAAGTGATTAAAGGTGCACCATGGAATATCGTTGTATTCTCTATTGGTATGTATCTTGTTG
TGTTTGGACTAAAAAATGTAGGTATTACAACGGTCCTTGGGGATGTTTTAACAAACATTTCAAATTATGGGTTATTTAGC
AGCATCATGGGTATCGGCTTTATAGCTGCTTTCTTATCTTCGATTATGAACAACATGCCAACTGTTTTAATAGATGCAAT
AGCGATTGGCCAATCCAGTGCTACAGGAATATTAAAAGAAGGCATGGTTTATGCGAATGTCATAGGTTCTGATTTAGGAC
CTAAAATTACGCCAATTGGTTCTTTAGCAACATTATTGTGGCTACATGTCTTAACACAAAAAGGTGTGAAGATTTCGTGG
GGAACATACTTTAAAACTGGAATTATCATCACTATTCCAGTCCTATTTGTAACACTCTTAGGTTTATACCTTACACTAAT
CATATTTTAA

Protein sequence :
MTILAIVIFLLTLTFVIWQPKGLDIGITALIGAVVAIITGVVSLSDVLEVTGIVWNATLTFVAVILISLILDEIGFFEWS
AIHMVKASNGNGLKMFVFIMLLGAIVAAFFANDGAALILTPIVLAMVRNLGFNQKVISPFIIASGFIADTTSLPLIVSNL
VNIVSADYFDIGFIEYFSRMIIPNIFSLIASILVLWLYFRKSIPKTFDTENLSDPKSAIKDSKLFKLSWIVLAVLLVGYL
VSEFIQIPVSIIAGIIAFIFVILARKSKAVHTKQVIKGAPWNIVVFSIGMYLVVFGLKNVGITTVLGDVLTNISNYGLFS
SIMGIGFIAAFLSSIMNNMPTVLIDAIAIGQSSATGILKEGMVYANVIGSDLGPKITPIGSLATLLWLHVLTQKGVKISW
GTYFKTGIIITIPVLFVTLLGLYLTLIIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 3e-155 93
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 1e-155 93
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 7e-155 91
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 3e-101 59

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB1 YP_040128.1 arsenical pump membrane protein 1 BAC0574 Protein 7e-164 99
arsB1 YP_040128.1 arsenical pump membrane protein 1 BAC0575 Protein 8e-162 97
arsB1 YP_040128.1 arsenical pump membrane protein 1 BAC0576 Protein 4e-99 59
arsB1 YP_040128.1 arsenical pump membrane protein 1 BAC0578 Protein 6e-100 59
arsB1 YP_040128.1 arsenical pump membrane protein 1 BAC0031 Protein 6e-98 58
arsB1 YP_040128.1 arsenical pump membrane protein 1 BAC0577 Protein 2e-99 58