Gene Information

Name : ccrA (SAR0060)
Accession : YP_039531.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : site-specific recombinase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG1961
EC number : -
Position : 64935 - 66284 bp
Length : 1350 bp
Strand : -
Note : Similar to Staphylococcus aureus, and site-specific recombinase CcrA TR:Q9XB96 (EMBL:D86934) (449 aa) fasta scores: E(): 4.4e-165, 95.323% id in 449 aa, and to Enterococcus faecalis bacteriophage phi-FC1 site-specific integrase TR:Q9XJF6 (EMBL:AF124258) (

DNA sequence :
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAACCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATAACACAATTAATTCAACAAGGACAGTGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATATCGTGTTCATATCTTAAGTGTGCATGATGGTTATTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATTATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGTCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAAAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAAAACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATGCTGTATCCCTACATTGATGAAATTCTTATCACAAAAAGTAAAACACT
AATGGGTATCTATTTCAAAAATGAACCCTTAAACATCGTCAATCAAACAACGCAATCGTCAATTGCATAA

Protein sequence :
MKQVIGYLRQSTMKQQSLAAQKQAIEAITEKHHIQHINFYSDKQSGRKDNRSGYRQITQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQKQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQNTIQ
NIIQKRFTLNMLYPYIDEILITKSKTLMGIYFKNEPLNIVNQTTQSSIA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ccrA YP_039531.1 site-specific recombinase Not tested Type-II SCCmec Protein 0.0 100
SERP2498 YP_190040.1 cassette chromosome recombinase A Not tested Type-II SCCmec Protein 0.0 100
ccrA NP_644854.1 cassette chromosome recombinase A Not tested Type-IV SCCmec Protein 0.0 99
ccrA YP_492758.1 cassette chromosome recombinase A Not tested Type-IV SCCmec Protein 0.0 97
ccrA2 BAC67560.1 cassette chromosome recombinase A2 Not tested Type-IVc SCCmec Protein 0.0 97
SAMSHR1132_00410 YP_005324564.1 site-specific recombinase Not tested Type-IIIinv SCCmec Protein 0.0 97
ccrA2 DAA01834.1 cassette chromosome recombinase A type 2 Not tested SCCpbp4 Protein 0.0 96
ccrA BAA82194.1 site-specific recombinase Not tested Type-II SCCmec Protein 0.0 96
SE0037 NP_763592.1 cassette chromosome recombinase A Not tested SCCpbp4 Protein 0.0 96
ccrA BAB72108.1 cassette chromosome recombinase A Not tested Type-IVa SCCmec Protein 0.0 96
ccrA NP_370586.1 cassette chromosome recombinase A Not tested Type-II SCCmec Protein 0.0 96
ccrA NP_373298.1 cassette chromosome recombinase A Not tested Type-II SCCmec Protein 0.0 96
ccrA BAB72127.1 cassette chromosome recombinase A Not tested Type-IVb SCCmec Protein 0.0 95
ccrA1 YP_005754052.1 site-specific recombinase CcrA1 Not tested Type-XI SCCmec Protein 4e-169 78
ccrA1 BAB83486.1 site-specific recombinase Not tested SCC 12263 Protein 3e-167 76
ccrA1 YP_184952.1 cassette chromosome recombinase A1 Not tested Type-I SCCmec Protein 2e-166 76
SSP0036 YP_300126.1 cassette chromosome recombinase A Not tested SCC15305RM Protein 3e-167 76
ccrA1 BAA86648.1 cassette chromosome recombinase A1 Not tested Type-I SCCmec Protein 1e-166 76
ccrA1 YP_042166.1 site-specific recombinase Not tested SCC476 Protein 1e-165 75
ccrA3 BAB47596.1 cassette chromosome recombinase A3 Not tested Type-III SCCmec Protein 6e-159 74
ccrA3 BAB46971.1 cassette chromosome recombinase A3 Not tested Type-IIIinv SCCmec Protein 6e-159 74
ccrA4 DAA01836.1 cassette chromosome recombinase A type 4 Not tested SCCpbp4 Protein 1e-109 50
SE0057 NP_763612.1 cassette chromosome recombinase A Not tested SCCpbp4 Protein 2e-109 50