Gene Information

Name : ccrB (SAR0059)
Accession : YP_039530.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : site-specific recombinase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG1961
EC number : -
Position : 63285 - 64913 bp
Length : 1629 bp
Strand : -
Note : Similar to Staphylococcus aureus site-specific recombinase CcrB TR:Q9XB94 (EMBL:D86934) (542 aa) fasta scores: E(): 5.6e-194, 99.815% id in 542 aa, and to lactococcal bacteriophage TP901-1 integrase Int TR:Q38184 (EMBL:X85213) (485 aa) fasta scores: E():

DNA sequence :
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTTTCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGATGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG

Protein sequence :
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKDGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SERP2499 YP_190041.1 cassette chromosome recombinase B Not tested Type-II SCCmec Protein 0.0 100
ccrB YP_039530.1 site-specific recombinase Not tested Type-II SCCmec Protein 0.0 100
ccrB2 BAC67561.1 cassette chromosome recombinase B2 Not tested Type-IVc SCCmec Protein 0.0 99
ccrB BAA82196.1 site-specific recombinase Not tested Type-II SCCmec Protein 0.0 99
ccrB NP_644853.1 cassette chromosome recombinase B Not tested Type-IV SCCmec Protein 0.0 99
SAMSHR1132_00400 YP_005324563.1 site-specific recombinase Not tested Type-IIIinv SCCmec Protein 0.0 99
ccrB YP_492757.1 cassette chromosome recombinase B Not tested Type-IV SCCmec Protein 0.0 99
ccrB NP_370585.1 cassette chromosome recombinase B Not tested Type-II SCCmec Protein 0.0 99
ccrB NP_373297.1 cassette chromosome recombinase B Not tested Type-II SCCmec Protein 0.0 99
ccrB BAB72109.1 cassette chromosome recombinase B Not tested Type-IVa SCCmec Protein 0.0 98
ccrB BAB72128.1 cassette chromosome recombinase B Not tested Type-IVb SCCmec Protein 0.0 98
SE0036 NP_763591.1 cassette chromosome recombinase B Not tested SCCpbp4 Protein 0.0 92
ccrB2 DAA01833.1 cassette chromosome recombinase B type 2 Not tested SCCpbp4 Protein 0.0 92
ccrB3 YP_005754051.1 site-specific recombinase CcrB3 Not tested Type-XI SCCmec Protein 0.0 87
ccrB3 BAB46972.1 cassette chromosome recombinase B3 Not tested Type-IIIinv SCCmec Protein 0.0 87
ccrB3 BAB47597.1 cassette chromosome recombinase B3 Not tested Type-III SCCmec Protein 0.0 87
SSP0035 YP_300125.1 cassette chromosome recombinase B Not tested SCC15305RM Protein 0.0 84
ccrB1 BAB83487.2 site-specific recombinase Not tested SCC 12263 Protein 0.0 81
ccrB YP_042165.1 site-specific recombinase Not tested SCC476 Protein 0.0 81
ccrB4 DAA01835.1 cassette chromosome recombinase B type 4 Not tested SCCpbp4 Protein 0.0 73
SE0056 NP_763611.1 cassette chromosome recombinase B Not tested SCCpbp4 Protein 0.0 73