Gene Information

Name : mecI (SAR0041)
Accession : YP_039517.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Resistance
Product : methicillin resistance regulatory protein MecI
Function : -
COG functional category : K : Transcription
COG ID : COG3682
EC number : -
Position : 48782 - 49126 bp
Length : 345 bp
Strand : +
Note : Previously sequenced as Staphylococcus epidermidis, and Staphylococcus aureus methicillin resistance regulatory protein MecI SW:MECI_STAEP (P26598) (123 aa) fasta scores: E(): 2.5e-41, 100.000% id in 114 aa. Similar to and to Staphylococcus haemolyticus b

DNA sequence :
ATGGATAATAAAACGTATGAAATATCATCTGCAGAATGGGAAGTTATGAATATCATTTGGATGAAAAAATATGCAAGTGC
GAATAATATAATAGAAGAAATACAAATGCAAAAGGACTGGAGTCCAAAAACCATTCGTACACTTATAACGAGATTGTATA
AAAAGGGATTTATAGATCGTAAAAAAGACAATAAAATTTTTCAATATTACTCTCTTGTAGAAGAAAGTGATATAAAATAT
AAAACATCTAAAAACTTTATCAATAAAGTATACAAAGGCGGTTTCAATTCACTTGTCTTAAACTTTGTAGAAAAAGAAGA
TCTATCACAAGATGAAATAGAATAA

Protein sequence :
MDNKTYEISSAEWEVMNIIWMKKYASANNIIEEIQMQKDWSPKTIRTLITRLYKKGFIDRKKDNKIFQYYSLVEESDIKY
KTSKNFINKVYKGGFNSLVLNFVEKEDLSQDEIE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mecI YP_039517.1 methicillin resistance regulatory protein MecI Not tested Type-II SCCmec Protein 4e-46 100
mecI NP_373280.1 methicillin resistance regulatory protein Not tested Type-II SCCmec Protein 3e-46 100
mecI YP_190060.1 methicillin-resistance regulatory protein MecI Not tested Type-II SCCmec Protein 3e-46 100
mecI BAA82218.1 methicillin resistance protein MecI Not tested Type-II SCCmec Protein 2e-46 100
mecI NP_370567.1 methicillin resistance regulatory protein Not tested Type-II SCCmec Protein 2e-45 99
mecI YP_005754043.1 methicillin resistance regulatory protein MecI Not tested Type-XI SCCmec Protein 3e-34 66
blaI YP_253677.1 beta-lactamase repressor Not tested ¥ÕSh1 Protein 9e-23 60

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mecI YP_039517.1 methicillin resistance regulatory protein MecI NC_002952.2861158.p0 Protein 1e-46 100
mecI YP_039517.1 methicillin resistance regulatory protein MecI NC_002745.1122814.p0 Protein 9e-47 100
mecI YP_039517.1 methicillin resistance regulatory protein MecI NC_002758.1120003.p0 Protein 5e-46 99
mecI YP_039517.1 methicillin resistance regulatory protein MecI NC_009782.5560220.p0 Protein 5e-46 99
mecI YP_039517.1 methicillin resistance regulatory protein MecI FR823292.1.gene6.p01 Protein 1e-34 66
mecI YP_039517.1 methicillin resistance regulatory protein MecI NC_002952.2858973.p0 Protein 3e-23 60
mecI YP_039517.1 methicillin resistance regulatory protein MecI NC_010419.6155809.p0 Protein 4e-23 60
mecI YP_039517.1 methicillin resistance regulatory protein MecI NC_010066.5774788.p0 Protein 3e-23 60
mecI YP_039517.1 methicillin resistance regulatory protein MecI NC_005054.2598289.p0 Protein 3e-23 60
mecI YP_039517.1 methicillin resistance regulatory protein MecI NC_003140.1122763.p0 Protein 4e-23 60
mecI YP_039517.1 methicillin resistance regulatory protein MecI NC_005011.2598314.p0 Protein 3e-23 60
mecI YP_039517.1 methicillin resistance regulatory protein MecI NC_005951.2853407.p0 Protein 3e-23 60
mecI YP_039517.1 methicillin resistance regulatory protein MecI AM180355.1.gene595.p Protein 4e-17 46