Gene Information

Name : SAR0460 (SAR0460)
Accession : YP_039909.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : Cys/Met metabolism PLP-dependent enzyme
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 488581 - 489723 bp
Length : 1143 bp
Strand : +
Note : Similar to Bacillus subtilis cystathionine gamma-lyase YrhB TR:O05394 (EMBL:U93874) (379 aa) fasta scores: E(): 7.2e-82, 57.632% id in 380 aa, and to Helicobacter pylori cystathionine gamma-synthase HP0106 SW:METB_HELPY (P56069) (380 aa) fasta scores: E()

DNA sequence :
ATGAATAAGAAAACGAAATTAATTCACGGTGGACACACAACGGACGACTATACAGGTGCAGTTACAACACCAATTTATCA
AACAAGTACATATTTACAAGATGATATTGGTGATTTACGTCAAGGATATGAATATTCTCGTACTGCGAATCCAACAAGAA
GTTCTGTAGAAAGCGTTATTGCGTCATTAGAAAATGGCAAACATGGCTTTGCATTTAGTTCAGGTGTTGCAGCAATCAGT
GCAGTTGTTATGCTGTTGGACAAAGGTGATCATATTATTTTAAATTCAGATGTATACGGCGGTACTTATCGCGCATTGAC
AAAAGTATTTACACGATTTGGCGTTGAAGTGGATTTTGTAGATACAACGCATACAGATTCAATTGTACAAGCGATACGCC
CAACAACAAAAATGTTATTTATTGAAACACCTTCTAATCCATTATTACGTGTTACTGACATTAAAAAGTCTGCTGAAATT
GCGAAAGAACACGGTTTGATTTCAGTCGTTGATAACACATTTATGACACTTTATTATCAGAATCCATTAGATTTAGGCAT
CGATATTGTCTTACATTCTGCAACGAAATATTTAGGTGGACATAGTGATGTCGTTGCTGGTTTAGTTGCAACATCGGATG
ACAAGCTTGCAGAACGTTTAGCATTTATTTCAAATTCAACAGGTGGCATTTTAGGACCTCAAGATAGTTATTTACTTGTG
AGGGGGATTAAAACATTAGGTTTACGTATGGAACAAATTAATCGCAGTGTTATTGAAATTATTAAAATGTTACAAGCACA
TCCAGCTGTGCAACAAGTGTTCCATCCAAGTATTGAAAGTCATTTAAATCATGATGTCCATATGGCTCAAGCGGATGGCC
ATACAGGTGTGATTGCTTTTGAAGTGAAAAATACAGAAAGTGCCAAACAATTGATTAAAGCAACATCGTATTACACATTA
GCTGAAAGTTTAGGTGCAGTGGAAAGTTTAATTTCAGTACCTGCATTGATGACACATGCATCTATTCCAGCAGATATTCG
AGCTAAAGAAGGTATTACAGACGGACTTGTAAGAATTTCTGTAGGTATTGAAGATACTGAAGATTTAGTAGATGATTTAA
AACAAGCACTAGATACGTTATAA

Protein sequence :
MNKKTKLIHGGHTTDDYTGAVTTPIYQTSTYLQDDIGDLRQGYEYSRTANPTRSSVESVIASLENGKHGFAFSSGVAAIS
AVVMLLDKGDHIILNSDVYGGTYRALTKVFTRFGVEVDFVDTTHTDSIVQAIRPTTKMLFIETPSNPLLRVTDIKKSAEI
AKEHGLISVVDNTFMTLYYQNPLDLGIDIVLHSATKYLGGHSDVVAGLVATSDDKLAERLAFISNSTGGILGPQDSYLLV
RGIKTLGLRMEQINRSVIEIIKMLQAHPAVQQVFHPSIESHLNHDVHMAQADGHTGVIAFEVKNTESAKQLIKATSYYTL
AESLGAVESLISVPALMTHASIPADIRAKEGITDGLVRISVGIEDTEDLVDDLKQALDTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-178 100
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-177 99
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-77 43