Gene Information

Name : SAR0434 (SAR0434)
Accession : YP_039885.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : restriction and modification system specificity protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0732
EC number : -
Position : 462913 - 464145 bp
Length : 1233 bp
Strand : +
Note : Similar to Lactococcus lactis type I restriction and modification system specificity subunit HsdS TR:Q9AJ85 (EMBL:AF142640) (410 aa) fasta scores: E(): 1.7e-20, 26.545% id in 437 aa, and to Streptococcus thermophilus restriction modification system specif

DNA sequence :
ATGAGTAATACACAAACGAAAAATGTGCCAGAGTTGAGATTCCCAGGGTTTGAAGGCGAATGGGAAGAGAAGAAGGTTGG
CGAGTTATTAGAATTTAAAAATGGTTTAAATAAAGGAAAAGAATATTTTGGCTCAGGATCGTCGATTGTTAACTTCAAAG
ATGTATTTAATAACAGGAGCTTAAATACAAATAATCTGACTGGAAAAGTTAATGTGAATAGCAAAGAACTAAAAAATTAT
TCTGTTGAAAAGGGTGATGTTTTTTTTACAAGGACTAGTGAGGTAATTGGTGAAATAGGTTATCCGTCTGTAATTTTAAA
TGACCCTGAAAATACTGTGTTTAGTGGATTTGTATTAAGAGGGCGGCCTAAATCAGGAATTGATTTAATAAATAATAATT
TTAAAAGATATGTCTTTTTTACTAATTCATTTAGAAAAGAAATGATTACAAAAAGTTCTATGACAACTAGAGCTTTAACA
TCAGGTAGCGCAATTAATAAAATGAAGGTCATATACCCTGTTTCGGCTAAAGAACAGAGAAAAATAGGTGACTTCTTCAG
CAAACTCGACCGACAAATTGAATTAGAAGAACAAAAGCTTGAATTACTTCAACAACAAAAAAAAGGCTATATGCAGAAAA
TCTTCTCACAGGAACTGCGATTCAAAGATGAGAATAGTGAAGATTATCCACATTGGGAAAATAGCAAAATAGAAAAATAT
TTAAAAGAGAGAAACGAACGTTCTGACAAAGGTCAAATGCTTTCAGTAACTATAAATAGTGGCATTATAAAATTTAGTGA
ATTGGATAGAAAAGATAATTCAAGTAAAGATAAAAGTAATTATAAAGTAGTTAGGAAAAATGATATTGCATATAATTCTA
TGAGAATGTGGCAAGGGGCTAGTGGTAGATCAAATTATAATGGGATTGTTAGCCCTGCATATACTGTGCTTTATCCAACA
CAAAATACTAGCTCATTATTTATTGGATATAAGTTTAAAACACATAGAATGATTCATAAATTTAAAATTAATTCACAAGG
ATTAACATCAGATACATGGAACTTAAAATATAAACAATTAAAAAATATAAATATAGATATACCTGTATTGGAGGAACAAG
AAAAGATAGGTGATTTCTTTAAAAAAATGGATATATTGATTAGTAAACAGAAAATAAAAATTGAAATATTAGAAAAAGAG
AAACAATCCTTTTTACAAAAGATGTTCTTATAA

Protein sequence :
MSNTQTKNVPELRFPGFEGEWEEKKVGELLEFKNGLNKGKEYFGSGSSIVNFKDVFNNRSLNTNNLTGKVNVNSKELKNY
SVEKGDVFFTRTSEVIGEIGYPSVILNDPENTVFSGFVLRGRPKSGIDLINNNFKRYVFFTNSFRKEMITKSSMTTRALT
SGSAINKMKVIYPVSAKEQRKIGDFFSKLDRQIELEEQKLELLQQQKKGYMQKIFSQELRFKDENSEDYPHWENSKIEKY
LKERNERSDKGQMLSVTINSGIIKFSELDRKDNSSKDKSNYKVVRKNDIAYNSMRMWQGASGRSNYNGIVSPAYTVLYPT
QNTSSLFIGYKFKTHRMIHKFKINSQGLTSDTWNLKYKQLKNINIDIPVLEEQEKIGDFFKKMDILISKQKIKIEILEKE
KQSFLQKMFL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0434 YP_039885.1 restriction and modification system specificity protein Not tested vSa¥á Protein 6e-164 100
SAUSA300_0406 YP_493120.1 putative restriction/modification system specificity protein Not tested vSa¥á Protein 3e-88 65
SACOL0477 YP_185367.1 type I restriction-modification system S subunit Not tested vSa¥á Protein 3e-88 65
hsdS NP_370956.1 restriction modification system specificity subunit Not tested vSa¥á Protein 3e-88 65
hsdS NP_373643.1 restriction modification system specificity subunit Not tested vSa¥á Protein 3e-88 65
hsdS YP_001331433.1 type I restriction modification system, site specificity determination subunit Not tested vSa¥á Protein 3e-88 65