Gene Information

Name : set4 (SAR0431)
Accession : YP_039882.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Virulence
Product : superantigen-like protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 460419 - 461102 bp
Length : 684 bp
Strand : +
Note : these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation

DNA sequence :
ATGAAATTGACAGCATTAGCAAAAGTAACATTAGCATTAGGGATTTTAACAACAGGAACTTTAACAACAGAGGCCCATTC
AGGTCATGCTAAACAAAATCAAAAGTCAGTAAACAAACATGACAAAGAAGCATTACACCGATACTACACTGGAAACTTTA
AGGAAATGAAAAACATTAATGCTTTGAGACATGGTAAAAATAACTTACGTTTTAAATATAGAGGGATGAAGACTCAAGTA
TTATTGCCTGGAGATGAGTACCGTAAATATCAACAGCGAAGACATACGGGCTTAGATGTGTTTTTTGTTCAAGAAAGAAG
AGACAAGCACGACATATCATATACTGTTGGTGGTGTAACAAAGACCAATAAAACATCCGGCTTTGTCAGCACACCAAGAT
TAAATGTTACAAAAGAAAAGGGTGAAGATGCTTTTGTGAAAGGTTACCCTTATGATATTAAAAAAGAAGAAATATCATTG
AAAGAGTTAGATTTTAAGTTGAGAAAGCATCTAATTGAAAAATACGGTCTTTATAAAACACTCTCAAAAGATGGTAGGAT
TAAAATTAGTCTGAAAGATGGTAGCTTTTATAACCTTGATTTAAGAACTAAATTAAAATTCAAACATATGGGGGAAGTCA
TAGATAGTAAACAAATTAAGGATATTGAAGTGAATTTAAAGTAA

Protein sequence :
MKLTALAKVTLALGILTTGTLTTEAHSGHAKQNQKSVNKHDKEALHRYYTGNFKEMKNINALRHGKNNLRFKYRGMKTQV
LLPGDEYRKYQQRRHTGLDVFFVQERRDKHDISYTVGGVTKTNKTSGFVSTPRLNVTKEKGEDAFVKGYPYDIKKEEISL
KELDFKLRKHLIEKYGLYKTLSKDGRIKISLKDGSFYNLDLRTKLKFKHMGEVIDSKQIKDIEVNLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
set4 YP_039882.1 superantigen-like protein Virulence vSa¥á Protein 6e-93 100
SAMSHR1132_03770 YP_005324899.1 exotoxin 4 Virulence vSa¥á Protein 1e-86 95
set14 NP_370953.1 superantigen-like protein Virulence vSa¥á Protein 4e-76 82
set14 NP_373640.1 superantigen-like protein Virulence vSa¥á Protein 4e-76 82
set10nm YP_001331431.1 superantigen-like protein Virulence vSa¥á Protein 4e-76 82
SAUSA300_0404 YP_493118.1 superantigen-like protein Virulence vSa¥á Protein 4e-76 82
SAS0393 YP_042518.1 superantigen-like protein Virulence vSa¥á Protein 3e-76 82
set25 NP_645208.1 superantigen-like protein Virulence vSa¥á Protein 3e-76 82
SACOL0474 YP_185364.1 superantigen-like protein Virulence vSa¥á Protein 4e-76 82
SAKOR_00413 YP_008490597.1 Exotoxin Virulence vSa¥á Protein 3e-76 82
set5 YP_039881.1 superantigen-like protein Virulence vSa¥á Protein 2e-24 50
SAS0392 YP_042517.1 superantigen-like protein Virulence vSa¥á Protein 2e-28 49
set24 NP_645207.1 superantigen-like protein Virulence vSa¥á Protein 2e-28 49
SAKOR_00412 YP_008490596.1 Exotoxin Virulence vSa¥á Protein 5e-28 49
set13 NP_373639.1 superantigen-like protein Virulence vSa¥á Protein 1e-28 48
set13 NP_370952.1 superantigen-like protein Virulence vSa¥á Protein 1e-28 48
SACOL0473 YP_185363.1 superantigen-like protein Virulence vSa¥á Protein 2e-29 47
set9nm YP_001331430.1 superantigen-like protein Virulence vSa¥á Protein 2e-29 47
SAUSA300_0403 YP_493117.1 superantigen-like protein Virulence vSa¥á Protein 2e-29 47
SAS0391 YP_042516.2 superantigen-like protein Virulence vSa¥á Protein 8e-28 45
set23 NP_645206.1 superantigen-like protein Virulence vSa¥á Protein 8e-28 45
set12 NP_370951.1 superantigen-like protein Virulence vSa¥á Protein 3e-28 45
set12 NP_373638.1 superantigen-like protein Virulence vSa¥á Protein 3e-28 45
set8nm YP_001331429.2 superantigen-like protein Virulence vSa¥á Protein 3e-28 45
SAUSA300_0402 YP_493116.1 superantigen-like protein Virulence vSa¥á Protein 3e-28 45
SAKOR_00411 YP_008490595.1 Exotoxin Virulence vSa¥á Protein 2e-28 45
SAS0396 YP_042522.1 superantigen-like protein Virulence vSa¥á Protein 6e-29 42
set26 NP_645211.1 superantigen-like protein Virulence vSa¥á Protein 6e-29 42
SAKOR_00410 YP_008490594.1 Exotoxin Virulence vSa¥á Protein 4e-23 41
set7nm YP_001331428.1 superantigen-like protein 7 Virulence vSa¥á Protein 1e-24 41
SAUSA300_0401 YP_493115.1 superantigen-like protein 7 Virulence vSa¥á Protein 1e-24 41
SAR0435 YP_039886.1 superantigen-like protein Virulence vSa¥á Protein 2e-29 41