Gene Information

Name : set3 (SAR0427)
Accession : YP_039879.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Virulence
Product : superantigen-like protein 5
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 457171 - 457875 bp
Length : 705 bp
Strand : +
Note : SSL5, SET3, SET10; bind P-selectin glycoprotein ligand-1 and inhibit P-selectin-mediated neutrophil rolling along the endothelium; these proteins share structural homology to known superantigens but do not exhibit any of the properties expected such as hi

DNA sequence : 
ATGAAGATGACAGCAATTGCGAAAGCCAGTTTAGCTCTAAGTATTTTAGCGACTGGGGTTATAACATCAACGGCTCAAAC
TGTAAATGCGAGCGAACATGAATCAAAATATGAAAATGTGACAAAAGATATCTTCGACTTGAGAGATTACTATAGTCGCG
CAAGTAAGGAACTTAAAAATGTTACTGGCTATCGTTATAGCAAAGGTGGCAAGCACTACCTTATCTTTGATAAAAATAGA
AAGTTCACAAGAATACAAATTTTTGGTAAAGATATAGAAAGGATTAAAAAACGTAAAAATCCAGGATTAGATATATTTGT
AGTTAAAGAAGCGGAAAATCGCAACGGCACAGTGTATTCATATGGTGGCGTTACTAAGAAAAATCAAGGCGCTTACTATG
ATTACTTAAGCGCACCTAGATTCGTTATTAAAAAAGAAGTAGGTGCAGGTGTTTCTGTGCATGTTAAAAGATACTACATT
TATAAGGAAGAGATTTCGCTGAAAGAACTTGATTTTAAATTACGACAGTATTTAATTCAAGATTTTGATCTGTATAAAAA
GTTTCCTAAAGCTAGCAAGATAAAAGTGACAATGAAAGATGGCGGCTATTATACGTTTGAACTCAATAAAAAGTTACAAA
CAAACCGAATGAGTGACGTCATAGATGGCAGAAATATTGAGAAAATAGAAGCCAATATTAGATAA

Protein sequence : 
MKMTAIAKASLALSILATGVITSTAQTVNASEHESKYENVTKDIFDLRDYYSRASKELKNVTGYRYSKGGKHYLIFDKNR
KFTRIQIFGKDIERIKKRKNPGLDIFVVKEAENRNGTVYSYGGVTKKNQGAYYDYLSAPRFVIKKEVGAGVSVHVKRYYI
YKEEISLKELDFKLRQYLIQDFDLYKKFPKASKIKVTMKDGGYYTFELNKKLQTNRMSDVIDGRNIEKIEANIR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
set3 YP_039879.1 superantigen-like protein 5 Virulence vSa¥á Protein 1e-97 100
SAKOR_00409 YP_008490593.1 Exotoxin Virulence vSa¥á Protein 9e-87 89
set10 NP_370949.1 superantigen-like protein 5 Virulence vSa¥á Protein 9e-86 88
set10 NP_373636.1 superantigen-like protein 5 Virulence vSa¥á Protein 9e-86 88
set5nm YP_001331426.1 superantigen-like protein 5 Virulence vSa¥á Protein 2e-85 88
SAUSA300_0399 YP_493113.1 superantigen-like protein 5 Virulence vSa¥á Protein 2e-85 88
set20 NP_645203.1 superantigen-like protein 5 Virulence vSa¥á Protein 2e-85 87
SAS0388 YP_042513.1 superantigen-like protein 5 Virulence vSa¥á Protein 2e-85 87
SAMSHR1132_03750 YP_005324897.1 exotoxin 3 Virulence vSa¥á Protein 6e-83 84
SAUSA300_0407 YP_493121.1 superantigen-like protein Virulence vSa¥á Protein 2e-33 48
SACOL0478 YP_185368.1 superantigen-like protein Virulence vSa¥á Protein 2e-33 48
set11nm YP_001331434.1 superantigen-like protein Virulence vSa¥á Protein 2e-33 48
SAS0396 YP_042522.1 superantigen-like protein Virulence vSa¥á Protein 7e-38 48
set26 NP_645211.1 superantigen-like protein Virulence vSa¥á Protein 7e-38 48
set15 NP_370957.1 superantigen-like protein Virulence vSa¥á Protein 4e-37 47
set15 NP_373644.1 superantigen-like protein Virulence vSa¥á Protein 4e-37 47
SAMSHR1132_03810 YP_005324902.1 exotoxin Virulence vSa¥á Protein 2e-34 47
SAR0435 YP_039886.1 superantigen-like protein Virulence vSa¥á Protein 2e-37 47
SAKOR_00417 YP_008490601.1 Exotoxin Not tested vSa¥á Protein 4e-35 46
SAR0422 YP_039874.1 superantigen-like protein Virulence vSa¥á Protein 2e-31 42
SAS0384 YP_042509.1 superantigen-like protein Virulence vSa¥á Protein 2e-32 42
set16 NP_645199.1 superantigen-like protein Virulence vSa¥á Protein 2e-32 42
SAKOR_00404 YP_008490588.1 Exotoxin Virulence vSa¥á Protein 2e-37 42
SAMSHR1132_03730 YP_005324895.1 exotoxin Virulence vSa¥á Protein 2e-20 41
SACOL0468 YP_185358.1 superantigen-like protein Virulence vSa¥á Protein 4e-36 41
set1nm YP_001331422.1 superantigen-like protein Virulence vSa¥á Protein 4e-36 41
SAUSA300_0395 YP_493109.1 superantigen-like protein Virulence vSa¥á Protein 4e-36 41