Gene Information

Name : SAR0424 (SAR0424)
Accession : YP_039876.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Virulence
Product : superantigen-like protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 454512 - 455543 bp
Length : 1032 bp
Strand : +
Note : these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation

DNA sequence : 
ATGAAAATAAGAACAATTGCGAAAGCGAGTATAGCGTTAGGGCTTGTAACAACAGGTGCAAGTATAGTAACAACGCAATC
GGCCAATGCAGAAGTAGCATCAGCACTTAAAGCAGGACAGTTAGCAAAGATAAACGTATCAACAAGCGCAATCACAACGA
CAGCGCAAGCAGTGAACGCAGAACAAAATCATACGGCTAATCCTGAACAGGCGGCAAAGTCTAACACAGAAAATGTATCA
ACATCGCTTTCAACTCAAACAGAACAGACGCCAAAATCTAACATACAAAAAGCAACACAACCAGCACCAAGCGGAACAAC
TCAGTCTTTACCAAATGCACAACCGCAATCAACACAACCAACACCAAGTGTAACAACACCGCCTTCATCTAATGTCGAAA
CACCACAACCAACATCGCCAACCACAAAACAAGCACAAAAGGAAATAAACCCTAAATTTAAAGGTTTAAGATCATATTAT
ACGAAATCAAGTTTAGAATTTAAAAATGAGTTGGGTATAATTATCAAAAAATGGACAACAATAAGATTTATGAATATTGT
TCCAGATTATTTCATATATAAAATAGCTTTAGTTGGAAAAGATGATAAGAAATATGGTGAAGGCGTGCATAGGCATGTCG
ATGTATTTATCGTTTTAGAACAAAATAAATATGGCGTAGACAAATACTCGGTCGGTGGTATCACAAAAGCAAATAGAAAG
AAAGTTGATTACAAAACTGGAATAAGTATTACTAAAGAAGATAAAAAAGGTACAATCTCACATGATGTTTCAGAATACAA
GATTACTAAAGAAGAGATTTCCTTGAAAGAACTTGATTTTAAATTGAGAAAACAACTCATTGAACAACATAATTTGTACG
GTAATATTGGTTCAGGAACAATCGTTATTAAAATGAAAAATGGTGGAAAGTACACGTTTGAATTACACAAAAAATTGCAA
CAACATCGCATGGCAGATGTTATTGATGGTACAAATATTGATAGAATTGAAGTGAATCTAAAATCATCGTGA

Protein sequence : 
MKIRTIAKASIALGLVTTGASIVTTQSANAEVASALKAGQLAKINVSTSAITTTAQAVNAEQNHTANPEQAAKSNTENVS
TSLSTQTEQTPKSNIQKATQPAPSGTTQSLPNAQPQSTQPTPSVTTPPSSNVETPQPTSPTTKQAQKEINPKFKGLRSYY
TKSSLEFKNELGIIIKKWTTIRFMNIVPDYFIYKIALVGKDDKKYGEGVHRHVDVFIVLEQNKYGVDKYSVGGITKANRK
KVDYKTGISITKEDKKGTISHDVSEYKITKEEISLKELDFKLRKQLIEQHNLYGNIGSGTIVIKMKNGGKYTFELHKKLQ
QHRMADVIDGTNIDRIEVNLKSS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0424 YP_039876.1 superantigen-like protein Virulence vSa¥á Protein 1e-149 100
SAR0425 YP_039877.1 superantigen-like protein Not tested vSa¥á Protein 1e-90 66
set9 NP_373635.1 superantigen-like protein Virulence vSa¥á Protein 2e-90 63
SAS0387 YP_042512.1 superantigen-like protein Virulence vSa¥á Protein 8e-95 63
set19 NP_645202.1 superantigen-like protein Virulence vSa¥á Protein 8e-95 63
set4nm YP_001331425.1 superantigen-like protein Virulence vSa¥á Protein 3e-92 62
SAUSA300_0398 YP_493112.1 superantigen-like protein Virulence vSa¥á Protein 3e-92 62
SAKOR_00408 YP_008490592.1 Exotoxin Virulence vSa¥á Protein 6e-94 62
SACOL0472 YP_185362.1 superantigen-like protein Virulence vSa¥á Protein 4e-91 61
SAMSHR1132_03740 YP_005324896.1 exotoxin Virulence vSa¥á Protein 2e-82 60
set8 NP_370948.1 superantigen-like protein Virulence vSa¥á Protein 3e-89 57
set8 NP_373634.1 superantigen-like protein Virulence vSa¥á Protein 3e-89 57
SAS0386 YP_042511.1 superantigen-like protein Virulence vSa¥á Protein 1e-89 57
set18 NP_645201.1 superantigen-like protein Virulence vSa¥á Protein 1e-89 57
SAKOR_00406 YP_008490590.1 Exotoxin Virulence vSa¥á Protein 2e-89 57
set3nm YP_001331424.1 superantigen-like protein Virulence vSa¥á Protein 7e-86 56
SAUSA300_0397 YP_493111.1 superantigen-like protein Virulence vSa¥á Protein 7e-86 56
SACOL0470 YP_185360.1 superantigen-like protein Virulence vSa¥á Protein 7e-86 56