Gene Information

Name : SAR0366 (SAR0366)
Accession : YP_039823.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG4974
EC number : -
Position : 410176 - 411390 bp
Length : 1215 bp
Strand : -
Note : Similar to bacteriophage phi PVL, and Staphylococcus aureus temperate phage phiSLT, integrase TR:O80068 (EMBL:AB009866) (401 aa) fasta scores: E(): 2e-52, 38.765% id in 405 aa, and to bacteriophage bIL312 integrase Int TR:Q9AZF9 (EMBL:AF323673) (382 aa) f

DNA sequence :
ATGTGGGTTCGTGAAATCACCAAAAACAATAGTACGGCCTATCGCTATTTAGAGCGCTATACAGACCCTTTAACTGGCAA
GTATAAAACAGTATCAGTTACACGTAACAAGAATAATGTACGTAGCCAAAAGGACGCTCAATTAGAATTAAATAAAATAA
TTGAGCAACGTTTGAAACATTACAGTACGAAACAACTTGAAAACTTAACGTTCCATGATGCGTGCGATGAATGGTTAGAG
CATTACAAGACACATTCAGGCTCGAAACCAACCACTATTAAAGAAAAGAAAAGTAATACTAATACAGTTAAAAATGCTAT
TGATAGCAAAGTACTCATCAGCAAGATTACGCACACCTACTTACAAAACATCATTAATGAATGGGCTAAATCACATAGTA
TTGGCCATGTTCAATCTCTTGTTATTGTTATTCGTTCCGTTTTCAAATATGCGTTTAAATATTATGATCTGCACGATATT
AGTGTGTTAGATAAAATAGATATACCTAAGAAAGCCCAAACCAGAAACGAGTTTCAAGCTAAACGTAATAACTATTTAGA
AGATAGCGAAGTAAAGGAGTTACTAGAGTGCTTCGACTATCTAATTAAACATAAGCGTCATGCTACGCGTAAACGTAACT
ATGAAATGGTAAAAGCATTAGTAGAATTTCAAATTAACAATGGAATGCGCATTGGCGAACTCCTAGCAATCAAGACAGAC
AATGTAGACGTGGAGAATAAAACACTAGAGATTGATGGCACAATTAACTGGGTTACAGATGTAGTAACTGGAGCATTTGG
AGTGAAAGAAACGACTAAGACGAGTAAGAGTTATCGAACAATAGGCCTCACAGCTCAAAGTATTAATTTACTTAAAAAAC
TCATGCTAGAAAATAAAAAAGAGAATCAGTGGAATGATAAATTCATAGATAGAGGTTATATATTTACTAACACTGCTGGT
AGCCCTATTGACTTAAATAAGGTGAATAATATTATTAAAGAAGCTACTGATATAAGTTCAATTAACAAGCGTGTGACAAC
GCACACATTACGTCACACACACATATCTACACTTGCGCAATTAGGAATTAACCTAAAAGCGATACAAGAGCGTGTAGGTC
ACTCGGACTATAAAACCACCTTAGAGATATACACACATGTTACTGATAAGATGGCAAAAGATATGATGAATAAATTAGAG
GGGATAGGGAGTTAG

Protein sequence :
MWVREITKNNSTAYRYLERYTDPLTGKYKTVSVTRNKNNVRSQKDAQLELNKIIEQRLKHYSTKQLENLTFHDACDEWLE
HYKTHSGSKPTTIKEKKSNTNTVKNAIDSKVLISKITHTYLQNIINEWAKSHSIGHVQSLVIVIRSVFKYAFKYYDLHDI
SVLDKIDIPKKAQTRNEFQAKRNNYLEDSEVKELLECFDYLIKHKRHATRKRNYEMVKALVEFQINNGMRIGELLAIKTD
NVDVENKTLEIDGTINWVTDVVTGAFGVKETTKTSKSYRTIGLTAQSINLLKKLMLENKKENQWNDKFIDRGYIFTNTAG
SPIDLNKVNNIIKEATDISSINKRVTTHTLRHTHISTLAQLGINLKAIQERVGHSDYKTTLEIYTHVTDKMAKDMMNKLE
GIGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0366 YP_039823.1 integrase Not tested SaPI4 Protein 1e-178 100
int AAC28969.1 integrase Not tested SaPI1 Protein 5e-78 47
int AAL04148.1 integrase-like protein Not tested SaPI3 Protein 2e-79 47
SAAV_0787 YP_003281710.1 pathogenicity island protein, integrase Virulence SaPIAv Protein 1e-78 47
SACOL0885 YP_185756.1 pathogenicity island protein, integrase Not tested vSa1 Protein 3e-79 47
int YP_493499.1 integrase Not tested SaPI5 Protein 2e-79 47
SAOV_0274 YP_005735791.1 putative prophage integrase Not tested ¥ÕSa1 Protein 4e-65 42