Gene Information

Name : SAR0355 (SAR0355)
Accession : YP_039812.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : Cys/Met metabolism PLP-dependent enzyme
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 401331 - 402491 bp
Length : 1161 bp
Strand : -
Note : Similar to Lactococcus lactis (subsp. cremoris) (Streptococcus cremoris) cystathionine beta-lyase MetC TR:Q9RAS9 (EMBL:AF131880) (380 aa) fasta scores: E(): 8e-61, 47.887% id in 355 aa, and to Lactobacillus reuteri cystathionine beta-lyase TR:Q9FCU8 (EMBL

DNA sequence :
ATGACACTTTCAAAAGAGACAGAAGTGATATTCGATTGGCGTAGAGGTGTGGAATATCATTCAGCTAACCCACCACTCTA
TGATTCTTCAACATTCCATCAAACAAGTCTTGGTGGCGATGTTAAATATGATTATGCACGAAGTGGCAACCCTAACCGTG
AACTTTTAGAAGAGAAGTTAGCACGATTAGAACAGGGGAAATTCGCTTTTGCTTTTGCATCAGGTATTGCTGCTATTTCA
GCAGTACTTTTGACTTTCAAATCTGGTGATCATGTCATCTTACCCGATGATGTATATGGCGGTACTTTTCGCCTCACTGA
GCAAATTTTGAATCGATTTAATATTGAATTTACAACCGTAGATACTACCAAGCTCGAACAAATCGAGGGTGCCATTCAAT
CAAACACAAAATTAATTTATATCGAAACACCATCGAATCCCTGTTTTAAAATTACTGATATCAAAGCTGTTTCTAAAATA
GCCGAAAAGCATGAACTACTGGTAGCTGTGGACAATACATTTATGACACCGTTAGGTCAATCACCTTTATTACTTGGCGC
TGATATCGTCATTCATAGTGCTACAAAATTTTTAAGTGGACATAGCGATTTAATTGCTGGTGCTGTCATTACTAATAATG
AAGCAATGAGTGAAGCACTTTATTTAATACAAAATGGTACGGGCAATATGTTATCTGCTCAAGATAGCTGGACGCTTGCT
AAACATTTGAAAACATTTCCAATCAGATTTAAACAATCTGTCGAAAACGCGCAAAAAATCGTGTCATTTTTAATAAAGCA
AGATGAAATTTCAGAAGTTTATTATCCGGGACTTACTGCTACTCATTTAGAACAAGCTAAAAATGGCGGTGCCGTTATTG
GCTTTCGTTTAGCTGATGAGTCTAAAGCACAACAATTTGTCGATGCACTGACATTACCACTCGTTTCAGTGAGTCTGGGC
GGTGTTGAAACGATACTTTCACATCCAGCAACAATGTCTCACGCTGCACTACCTGAAGAAGTGAGACAAGAACGTGGTAT
CACTTTCGGTCTGTTCCGATTAAGTGTTGGTCTCGAAGATCCTGATGAACTCATTGCAGACATCAAATACGCATTAAAGG
AGGCATTCAATGAGTCAATTCCTCACACACTTGAAAGATAA

Protein sequence :
MTLSKETEVIFDWRRGVEYHSANPPLYDSSTFHQTSLGGDVKYDYARSGNPNRELLEEKLARLEQGKFAFAFASGIAAIS
AVLLTFKSGDHVILPDDVYGGTFRLTEQILNRFNIEFTTVDTTKLEQIEGAIQSNTKLIYIETPSNPCFKITDIKAVSKI
AEKHELLVAVDNTFMTPLGQSPLLLGADIVIHSATKFLSGHSDLIAGAVITNNEAMSEALYLIQNGTGNMLSAQDSWTLA
KHLKTFPIRFKQSVENAQKIVSFLIKQDEISEVYYPGLTATHLEQAKNGGAVIGFRLADESKAQQFVDALTLPLVSVSLG
GVETILSHPATMSHAALPEEVRQERGITFGLFRLSVGLEDPDELIADIKYALKEAFNESIPHTLER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-63 48
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-58 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-59 43