Gene Information

Name : vraD (SAR2781)
Accession : YP_042118.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Resistance
Product : ABC transporter ATP-binding protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : -
Position : 2887715 - 2888473 bp
Length : 759 bp
Strand : +
Note : Previously sequenced as Staphylococcus aureus ABC transporter ATP-binding protein, up-regulated in vancomycin-resistant strains, VraD TR:Q9RL74 (EMBL:Y18641) (252 aa) fasta scores: E(): 4e-80, 99.6% id in 252 aa. Similar to Bacillus halodurans ABC transpo

DNA sequence : 
ATGACGATATTATCAGTGCAACATGTTTCAAAAACATACGGTAAAAAGCACACATTTCAAGCACTTAAAGATATTAACTT
TGACATACAAAAAGGCGAATTCGTTGCGATTATGGGGCCTTCTGGATCAGGTAAGACAACCTTATTAAATGTACTAAGTT
CAATTGACCAAATTTCTAGCGGTAGCGTGATTGCTAACGGACAAGAGCTTAATAAACTTAATCAAAAAGCACTTGCCAAA
TTCCGTAAAGAATCATTAGGTTTCATCTTCCAAGATTACAGTATTCTGCCGACATTAACTGTTAAAGAAAACATTATGTT
ACCTTTATCTGTTCAAAAAATGTCGAAAGCAACAATGGAAGAAAATTATAAAGCAATCACAACAGCATTAGGTATTTATG
ACCTAGGAAATAAATACCCTAGCGAATTATCTGGTGGTCAACAACAAAGAACTGCAGCAGCGAGAGCATTTGTTCACAAA
CCACAAATCATATTTGCAGATGAGCCAACAGGCGCACTCGACTCGAAAAGTGCAAATGATTTATTACAACGTTTGGAAGA
AATGAATAAATCGTTTGATACCACAATTGTCATGGTTACACATGATCCGGTTGCAGCAAGTTTTGCAGAACGTGTCATCA
TGCTAAAAGATGGCCAAATTCATACACAACTTTATCAGGAAGGACGTTCTAAACAGGCCTTTTATAAAGACATTGTACAT
CTTCAATCAGTATTAGGTGGTGTCTCAAATGACATTTAA

Protein sequence : 
MTILSVQHVSKTYGKKHTFQALKDINFDIQKGEFVAIMGPSGSGKTTLLNVLSSIDQISSGSVIANGQELNKLNQKALAK
FRKESLGFIFQDYSILPTLTVKENIMLPLSVQKMSKATMEENYKAITTALGIYDLGNKYPSELSGGQQQRTAAARAFVHK
PQIIFADEPTGALDSKSANDLLQRLEEMNKSFDTTIVMVTHDPVAASFAERVIMLKDGQIHTQLYQEGRSKQAFYKDIVH
LQSVLGGVSNDI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 5e-32 45
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 5e-32 45
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 5e-32 45
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 3e-30 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
vraD YP_042118.1 ABC transporter ATP-binding protein CP001581.1.gene798.p Protein 1e-35 43
vraD YP_042118.1 ABC transporter ATP-binding protein CP001581.1.gene598.p Protein 2e-37 43
vraD YP_042118.1 ABC transporter ATP-binding protein NC_012469.1.7686878. Protein 4e-36 43