Gene Information

Name : azi; div (SAR2728)
Accession : YP_042070.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 2831252 - 2833642 bp
Length : 2391 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGAAACATAAACTAGATGTTACGATAAACGAATTAAGACTAAAGTCGATTAGAAAAATAGTGAAACGCATCAATACATG
GAGCGATGAAGTTAAATCATATTCTGATGATGTGTTAAAACAAAAGACACTAGAATTTAAAGAACGTATAGCATCAGGAG
TTGATACACTAGACACATTGTTACCTGAAGCTTATGCAGTGGCACGTGAAGCGAGCTGGAGAGTATTAGGTATGTATCCT
AAAGAAGTTCAGTTAATCGGAGCGATTGTATTGCATGAAGGTAACATTGCGGAGATGCAAACAGGCGAAGGTAAAACATT
AACAGCAACGATGCCTTTATATTTAAATGCACTTTCGGGAAAAGGAACATATTTAATTACAACGAATGATTATTTAGCGA
AGCGTGATTTTGAAGAGATGCAACCATTATATGAATGGTTAGGTTTAACTGCTTCATTAGGTTTTGTTGATATTGTGGAT
TATGAGTATCAAAAAGGGGAAAAACGTAATATATATGAACATGATATTATATATACAACTAATGGACGTCTCGGTTTTGA
TTATTTAATTGATAATTTGGCAGATAGTGCGGAAGGGAAATTTTTACCACAATTAAATTACGGTATTATTGATGAAGTGG
ATTCAATCATTTTAGATGCTGCGCAAACACCATTAGTTATTTCGGGCGCACCAAGATTACAATCAAATCTATTTCATATT
GTGAAAGAGTTTGTAGATACATTGATTGAAGACGTGCATTTTAAAATGAAGAAGACCAAAAAAGAAATATGGCTGTTAAA
TCAAGGTATTGAAGCGGCACAATCATACTTTAATGTTGAAGATTTATATAGCGAACAAGCGATGGTCTTAGTGCGTAATA
TTAATCTAGCACTGCGCGCGCAATATTTGTTTGAATCTAATGTCGATTATTTCGTATATAATGGTGATATTGTTTTAATT
GACCGTATTACAGGTCGTATGTTACCGGGAACTAAGTTGCAAGCTGGACTCCACCAAGCTATTGAAGCGAAAGAAGGTAT
GGAGGTTTCAACAGATAAAAGTGTTATGGCAACAATTACCTTTCAGAATTTATTTAAACTTTTTGAATCATTTTCAGGTA
TGACAGCTACAGGAAAATTAGGCGAATCAGAGTTCTTTGATTTGTATTCAAAAATAGTCGTACAAGTACCAACTGATAAA
GCGATTCAACGTATCGATGAACCAGATAAAGTGTTTCGTTCAGTTGATGAGAAAAACATCGCAATGATTCATGATATAGT
TGAACTTCATGAAACGGGGCGACCGGTTTTACTCATAACGAGAACTGCTGAAGCGGCTGAATACTTTTCAAAAGTATTTT
TCCAAATGGATATTCCTAATAATTTACTCATTGCGCAAAATGTTGCAAAAGAAGCGCAGATGATAGCTGAAGCAGGGCAA
ATTGGTTCCATGACTGTTGCGACTAGTATGGCAGGTCGAGGCACAGATATTAAACTTGGTGAAGGTGTCGAAGCATTAGG
TGGATTAGCTGTTATTATTCATGAACATATGGAAAATAGCCGTGTAGACAGGCAATTACGTGGTCGTTCTGGTAGACAAG
GGGATCCAGGATCATCTTGTATATATATTTCACTAGATGATTATTTAGTTAAGCGATGGAGCGATAGTAATTTAGCGGAA
AATAATCAATTATATTCATTAGATGCACAACGATTATCGCAAAGTAGTTTGTTTAATCGCAAAGTTAAGCAAATTGTAGT
TAAAGCGCAGCGTATCTCGGAAGAACAAGGGGTTAAAGCTCGTGAAATGGCTAATGAATTTGAAAAAAGCATTAGTATAC
AGCGAGATCTTGTATACGAGGAACGCAATCGAGTTTTAGAAATAGATGATGCTGAGAATCGAGATTTTAAAGTGTTAGCT
AAAGATGTGTTTGAAATGTTTGTAAATGAGGAAAAGGTGCTAACAAAATCGCGTGTTGTCGAGTATATTTATCAAAATTT
AAGTTTCCAATTTAATAAAGATGTGGCTTGTGTTAATTTTAAAGATAAGCAAGCTGTAGTAACATTTTTATTAGAGCAAT
TTGAAAAGCAAATAGCTTTGAATCGTAAAAACATGCAAAGTGCATATTATTATAATATTTTCGTTCAAAAAGTCTTTTTA
AAAGCAATTGATTCATGTTGGTTAGAACAAGTCGACTATTTACAACAATTAAAAGCAAACGTTAATCAACGACAAAATGG
GCAACGTAACGCTATTTTTGAATACCATAGAGTTGCATTAGATTCATTTGAAGTTATGACACGAAATATCAAAAAAAGAA
TGGTGAAAAATATTTGTCAAAGCATGATTACATTTGATAAAGAAGGTATGCCAGTTATACATTTTCCATAA

Protein sequence :
MKHKLDVTINELRLKSIRKIVKRINTWSDEVKSYSDDVLKQKTLEFKERIASGVDTLDTLLPEAYAVAREASWRVLGMYP
KEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVD
YEYQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHI
VKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLI
DRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQVPTDK
AIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVFFQMDIPNNLLIAQNVAKEAQMIAEAGQ
IGSMTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAE
NNQLYSLDAQRLSQSSLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENRDFKVLA
KDVFEMFVNEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKDKQAVVTFLLEQFEKQIALNRKNMQSAYYYNIFVQKVFL
KAIDSCWLEQVDYLQQLKANVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKEGMPVIHFP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 8e-154 46