Gene Information

Name : hlgB (SAR2511)
Accession : YP_041861.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Virulence
Product : gamma-hemolysin component C precursor
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2585585 - 2586562 bp
Length : 978 bp
Strand : +
Note : Identical to Staphylococcus aureus HlgB-like precursor Luk F-R TR:Q57227 (EMBL:X81586) (325 aa) fasta scores: E(): 1.4e-125, 100% id in 325 aa. Similar to Staphylococcus aureus leukocidin F subunit precursor LukF SW:LUKF_STAAU (P31715) (323 aa) fasta scor

DNA sequence :
ATGAACATGAATAAATTAGTCAAATCATCCGTTGCTACGTCTATGGCATTATTATTACTTTCTAATACTGCAAATGCTGA
AGGCAAAATCACACCAGTTAGCGTCAAAAAAGTAGATGATAAAGTTACTTTATACAAAACTACAGCTACAGCAGATTCAG
ATAAATTCAAAATTTCACAGATTTTAACATTCAATTTCATCAAAGATAAAAGTTATGATAAAGATACTTTAGTGCTTAAA
GCTGCAGGTAATATTAACTCAGGTTATGAAAGACCAAATCCTAAAGACTACGACTTTTCAAAAATATATTGGGGTGCAAA
ATACAATGTGTCTATCAGTTCACAATCTAATGATTCGGTTAATGTAGTAGACTATGCACCTAAAAATCAAAATGAAGAAT
TTCAAGTTCAAAACACTTTAGGCTATACATTTGGTGGTGACATCAGTATCTCTAATGGTTTATCTGGCGGACTTAACGGA
AACACTGCTTTTTCTGAAACAATTAATTATAAACAAGAAAGTTACAGAACAACATTAAGTCGCAACACAAATTATAAAAA
TGTCGGTTGGGGTGTAGAAGCACATAAAATTATGAATAATGGTTGGGGACCTTATGGACGAGATAGCTTCCACCCAACAT
ATGGTAATGAACTCTTCTTAGCTGGCAGACAAAGCAGTGCATACGCTGGCCAAAACTTCATAGCGCAACACCAAATGCCA
TTATTATCTAGAAGTAACTTCAATCCAGAATTTTTAAGCGTACTATCACACAGACAAGATGGCGCTAAAAAATCTAAAAT
TACAGTAACTTATCAACGTGAAATGGATTTATACCAAATTCGTTGGAATGGCTTCTACTGGGCAGGCGCGAATTATAAAA
ACTTTAAAACTAGAACATTTAAATCAACATATGAAATTGATTGGGAAAATCACAAAGTGAAATTGTTAGATACAAAAGAA
ACTGAAAACAATAAATAA

Protein sequence :
MNMNKLVKSSVATSMALLLLSNTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLK
AAGNINSGYERPNPKDYDFSKIYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNG
NTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMP
LLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKE
TENNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lukD NP_374926.1 leukotoxin, LukD Virulence vSa¥â Protein 3e-104 77
lukD YP_186707.1 leukotoxin LukD Virulence vSa¥â Protein 2e-104 77
lukD NP_646584.1 leukotoxin Virulence vSa¥â Protein 2e-104 77
lukD YP_001332752.1 leukocidin LukD precursor Virulence vSa¥â Protein 2e-104 77
lukD YP_494459.1 leukotoxin LukD Virulence vSa¥â Protein 2e-104 77
SAKOR_01767 YP_008491955.1 Leukocidin F subunit lukD Virulence vSa¥â Protein 3e-104 77
lukD NP_372343.2 leukotoxin F-subunit Virulence vSa¥â Protein 3e-104 77
lukF NP_646195.1 Panton-Valentine leukocidin chain F precursor Virulence ¥ÕSa2 Protein 2e-92 73
lukF-PV YP_494078.1 Panton-Valentine leukocidin, LukF-PV Virulence ¥ÕSa2 Protein 2e-92 73
SAOV_1908 YP_005737353.1 Panton-Valentine leukocidin LukF-PV chain precursor Virulence ¥ÕSa3 Protein 2e-90 71

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hlgB YP_041861.1 gamma-hemolysin component C precursor VFG1275 Protein 4e-128 98
hlgB YP_041861.1 gamma-hemolysin component C precursor VFG1276 Protein 7e-93 73