Gene Information

Name : hysA2 (SAR2292)
Accession : YP_041646.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Virulence
Product : hyaluronate lyase precursor 2
Function : -
COG functional category : -
COG ID : -
EC number : 4.2.2.1
Position : 2375721 - 2378147 bp
Length : 2427 bp
Strand : +
Note : Similar to Staphylococcus aureus hyaluronate lyase precursor HysA SW:HYSA_STAAU (Q59801) (807 aa) fasta scores: E(): 0, 87.5% id in 808 aa, and to Streptococcus pneumoniae hyaluronate lyase precursor SP0314 SW:HYSA_STRPN (Q54873) (949 aa) fasta scores: E(

DNA sequence :
ATGACATATAGAATGAAGAAATGGCAAAAATTGTCCACCATTACGTTATTAATGGCTGGTGTGATTACTTTGAATGGTGG
TGAATTCAGAAGTATTGATAAACATCAAATCGCTGTGGCTGATACGAATGTTCAAACGACAGATTATGAAAAGTTGAGGA
ACATATGGCTGGACGTTAACTATGGTTATGATAAGTATGATGAGAATAATCCAGATATGAAGAAGAAGTTTGAGGCTACG
GAGAATGAGGCAGAGAAATTACTCAAGGAAATGAAAACTGAAAGTGATAGGAAATACTTGTGGGAAAGCTCAAAAGATTT
AGATACGAAGTCTGCGGATATGACTCGTACCTATCGTAATATTGAGAAAATCTCAGAAGCGATGAAACATAAAAATACTA
AATTAAAAACAGATGAAAACAAGACAAAAGTAAAAGATGCACTTGAGTGGCTGCATAAAAATGCATATGGAAAAGAACCA
GATAAAAAAGTTGCTGATTTGACCTCAAACTTTAAAAATAAAACTTCTAGAAATACCAACTTAAATTGGTGGGATTATGA
AATTGGAACACCTAGAGCATTAACAAATACGCTTATACTCTTACAAGAAGATTTCACTGATGAAGAAAAGAAAAAATATA
CAGCTCCTATTAAAACTTTCGCCCCAGATAGTGACAAAATATTATCTTCTGTAGGAAAATCTGAACCTGCTAAAGGCGGA
AATTTAGTAGACATTTCTAAAGTAAAACTTTTAGAAAGTATTATCGAAGAAGACAAAGATATGATGAAAAAGTCTATAGA
TTCATTTAATACAGTCTTCACTTACGCGCAAAATTCTGCCACTGGAAAAGAACGTAATGGATTCTATAAAGATGGCTCTT
ACATTGATCATCAAGACGTCCCATACACTGGTGCTTATGGCGTTGTACTATTAGAGGGTATTTCTCAAATGATGCCGATG
ATAAAAGAAACACCTTTTAATGATAGTAACCAAAATGATACAACCTTAAAATCATGGATTGACGACGGATTTATGCCACT
CATTTATAAAGGTGAAATGATGGATTTATCAAGAGGTAGAGCTATCAGTCGTGAAAATGAAACGAGTCACTCAGCATCTG
CAACAGTAATGAAATCATTGTTGAGATTGAGTGATACCATGGATAAGTCTACAAAAGCTAAATATAAAAAGATTGTCAAG
ACTTCAGTAGAGTCAGATTCAAGTTATAAACAAACCGATTATTTAAGCTCTTATTCGGATATAAGCAAAATGAAGTCTTT
AATGGAAGACAGCACTATTTCTACTAACGGTTTAACACAACAACTTAAAATATATAATGACATGGATCGTGTCACCTATC
ACAATAAAGGCTTAGACTTTGCATTTGGTTTAAGTATGACGTCGAAAAACGTCGCACGTTACGAAAGTATCAACGGAGAG
AACTTAAAAGGTTGGCACACTGGTGCTGGAATGTCTTATTTATACAATAGCGATGTGAAACACTACCGTGATAACTTCTG
GGCGACAGCTGATATGAAACGTTTAGCAGGTACTACAACTTTAGATAATGAAGAACCTAAAAGTACGGATGTTAAAAAGT
CTAGTAAAACTTTTGTAGGAGGAACAAAATTCGATGACCAACATGCTAGTATCGGAATGGATTTTGAAAATCAGGACAAA
ACTTTAACTGCCAAAAAATCATATTTCATATTAAACGATAAAATTGTCTTCTTAGGAACTGGCATTAAAAGTACTGATTC
ATCAAAGAATCCAGTTACAACGATTGAAAATCGCAAAGCGAATGATTATAAATTATATAAAGATGATACGCAAACAACCA
ATTCCGATAATCAGGAAACCAATTCCCTCTTTTTAGAGTCAACGAATAGCACTCAAAACAATATAGGTTATCATTTTTTA
AACGAATCGAAAATAACTGTAAAAAAAGAAAGTCATACTGGTAAGTGGAGTGATATAAATAAAAGCCAAAAGGATATACA
AAAAACTGATGAGTATTATGAAGTAACTCAAAAGCATTCTAATACAGATAGTAAATATGCATATGTGTTGTATCCAGGCT
TATCTAAAGATGTCTTTAAATCCAAAGCAAGCAAAGTAACTGTCGTTAAGCAAGAAGATGACTTCCACGTTGTGAAAGAT
AATGAATCGGTTTGGGCTGGTATCAATTATAGTGATAGCGCTAAAACTTTTGAAATTAATAACACTAAAGTCGAAGTTAA
AGCCAAAGGAATGTTTATTCTTACAAAGAAAGATGATAACACTTATGAATGTAGCTTCTATAATCCCGAATCTACAAATT
CCGTTTCAGATATTGAATCTAAAATTTCAATGACTGGATACTCTATTATAAACAAAAATACGTCGACTTCTAATGAATCC
GGCGTACGCTTTGAATTAACTAAATAA

Protein sequence :
MTYRMKKWQKLSTITLLMAGVITLNGGEFRSIDKHQIAVADTNVQTTDYEKLRNIWLDVNYGYDKYDENNPDMKKKFEAT
ENEAEKLLKEMKTESDRKYLWESSKDLDTKSADMTRTYRNIEKISEAMKHKNTKLKTDENKTKVKDALEWLHKNAYGKEP
DKKVADLTSNFKNKTSRNTNLNWWDYEIGTPRALTNTLILLQEDFTDEEKKKYTAPIKTFAPDSDKILSSVGKSEPAKGG
NLVDISKVKLLESIIEEDKDMMKKSIDSFNTVFTYAQNSATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPM
IKETPFNDSNQNDTTLKSWIDDGFMPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDTMDKSTKAKYKKIVK
TSVESDSSYKQTDYLSSYSDISKMKSLMEDSTISTNGLTQQLKIYNDMDRVTYHNKGLDFAFGLSMTSKNVARYESINGE
NLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLDNEEPKSTDVKKSSKTFVGGTKFDDQHASIGMDFENQDK
TLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANDYKLYKDDTQTTNSDNQETNSLFLESTNSTQNNIGYHFL
NESKITVKKESHTGKWSDINKSQKDIQKTDEYYEVTQKHSNTDSKYAYVLYPGLSKDVFKSKASKVTVVKQEDDFHVVKD
NESVWAGINYSDSAKTFEINNTKVEVKAKGMFILTKKDDNTYECSFYNPESTNSVSDIESKISMTGYSIINKNTSTSNES
GVRFELTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hysA1 YP_041274.1 hyaluronate lyase precursor 1 Virulence vSa¥â Protein 0.0 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hysA2 YP_041646.1 hyaluronate lyase precursor 2 VFG1315 Protein 0.0 91