Gene Information

Name : pyn (SAR2224)
Accession : YP_041584.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : pyrimidine-nucleoside phosphorylase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0213
EC number : 2.4.2.2
Position : 2291698 - 2292999 bp
Length : 1302 bp
Strand : -
Note : Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway

DNA sequence :
ATGAGAATGATAGACATTATTGAGAAAAAGCGTGACGGTCATACACTAACAACGGAAGAAATTAATTTCTTTATTGACGG
CTATGTTAAAGGGGATATTCCTGATTATCAAGCGTCAAGTTTAGCAATGGCGATTTATTTCCAAGATATGAACGATGATG
AGCGTGCAGCATTAACGATGGCTATGGTTAATTCTGGTGATATGATAGATTTGAGTGATATTAAAGGTGTCAAAGTAGAT
AAGCACTCAACAGGTGGTGTAGGAGATACAACTACATTGGTTTTAGCACCATTAGTAGCAGCTGTAGATGTTCCTGTTGC
AAAAATGAGTGGGCGTGGATTAGGTCATACAGGTGGTACGATTGATAAATTAGAAGCAATTGATGGTTTTCATGTTGAAA
TAGATGAAGCAACATTTGTGAAATTGGTTAATGAAAATAAAGTGGCAGTTGTAGGACAATCAGGAAATTTAACTCCTGCA
GATAAAAAATTATATGCCTTAAGGGATGTTACTGGTACTGTCAATTCAATACCATTAATTGCCTCTTCAATTATGAGTAA
AAAGATTGCTGCTGGTGCAGATGCAATTGTATTAGATGTAAAAACTGGTAGCGGTGCATTTATGAAAACATTAGAAGATG
CTGAAGCATTAGCGCACGCAATGGTACGTATTGGTAATAATGTGGGACGTAATACGATGGCGATTATTTCTGATATGAAT
CAGCCACTTGGACGTGCGATTGGCAATGCGCTTGAGTTACAAGAAGCAATTGATACGTTGAAAGGACAAGGTCCGAAAGA
TTTAACAGAACTTGTATTAACATTAGGTTCTCAAATGGTTGTACTTGCAAACAAAGCTGAAACGCTTGAAGAAGCGAGAG
CGTTGCTAATTGAGGCAATTGATTCAGGTGCAGCATTAGAAAAATTCAAAACATTTATTAAAAACCAAGGTGGCGACAAA
ACAGTTATTGACCATCCAGAGCGTTTGCCACAAGCTCAATATCAAATCGAATATAAAGCTAAAAAATCAGGTTATGTGAC
TGAGTTAGTCTCTAACGATATAGGTGTCGCTTCGATGATGTTAGGAGCGGGACGTTTAACAAAAGAGGATGATATTGATT
TAGCGGTTGGTATTGTTTTAAATAAAAAAATTGGTGATAAAGTAGAAGAAGGAGAATCATTATTAACGATTCACAGTAAT
CGCCAAGATGTAGACGATGTTGTTAAAAAATTAGATTCAAGCATAACAATTGCTGATTATGTTGTATCGCCTACATTAAT
TCATAAAATAATTACAGAGTAG

Protein sequence :
MRMIDIIEKKRDGHTLTTEEINFFIDGYVKGDIPDYQASSLAMAIYFQDMNDDERAALTMAMVNSGDMIDLSDIKGVKVD
KHSTGGVGDTTTLVLAPLVAAVDVPVAKMSGRGLGHTGGTIDKLEAIDGFHVEIDEATFVKLVNENKVAVVGQSGNLTPA
DKKLYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGSGAFMKTLEDAEALAHAMVRIGNNVGRNTMAIISDMN
QPLGRAIGNALELQEAIDTLKGQGPKDLTELVLTLGSQMVVLANKAETLEEARALLIEAIDSGAALEKFKTFIKNQGGDK
TVIDHPERLPQAQYQIEYKAKKSGYVTELVSNDIGVASMMLGAGRLTKEDDIDLAVGIVLNKKIGDKVEEGESLLTIHSN
RQDVDDVVKKLDSSITIADYVVSPTLIHKIITE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
deoA YP_005163381.1 Thymidine phosphorylase Not tested Not named Protein 2e-74 47