Gene Information

Name : SAR2210 (SAR2210)
Accession : YP_041570.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 2276632 - 2278059 bp
Length : 1428 bp
Strand : -
Note : Similar to Bacillus subtilis betaine aldehyde dehydrogenase GbsA SW:DHAB_BACSU (P71016) (490 aa) fasta scores: E(): 1.2e-59, 40.33% id in 476 aa, and to Caulobacter crescentus aldehyde dehydrogenase CC0419 TR:Q9AB15 (EMBL:AE005714) (479 aa) fasta scores:

DNA sequence :
ATGAGAGACTACACAAAGCAATACATTAATGGCGAATGGGTAGAAAGTAATAGTAATGAAACGATAGAAGTTATAAATCC
AGCAACCGAAGAAGTAATCGGGAAAGTTGCTAAAGGTAATAAAGCTGATGTTGATAAAGCCGTCGAGGCGGCAGACAATG
TTTATTTAGAGTTCCGTCATACATCTGTGAAAGAAAGACAAGCGTTATTAGATAAAATTGTAAAAGAATATGAAAACAGA
AAAGACGATATTGTACAAGCTATTACGGATGAGTTAGGTGCTCCTTTATCATTATCTGAGCGTGTCCATTATCAAATGGG
ACTAAACCATTTTGTTGCAGCGAGAGACGCATTAGATAATTACGAATTTGAAGAACGCCGCGGAGATGATTTAGTTGTTA
AAGAAGCAATCGGTGTATCTGGCTTAATTACACCGTGGAACTTCCCTACAAACCAAACATCATTAAAATTAGCAGCAGCA
TTTGCGGCTGGTAGTCCAGTTGTACTTAAACCATCTGAAGAAACACCATTTGCAGCTGTTATTTTAGCTGAGATTTTTGA
TAAAGTCGGTGTTCCTAAAGGTGTATTTAACCTTGTTAATGGTGATGGTGCAGGCGTTGGGAATCCTTTATCTGAACATC
CTAAAGTACGCATGATGTCATTTACAGGATCAGGCCCTACTGGTTCTAAAATTATGGAAAAAGCTGCTAAAGATTTTAAA
AAGGTATCATTAGAGCTTGGTGGCAAATCACCATACATCGTCCTAGATGACGTAGATATTAAAGAAGCGGCTAAAGCAAC
AACAGGCAAAGTTGTTAATAATACTGGTCAAGTATGTACAGCTGGTACACGCGTTTTAGTGCCTAACAAAATTAAAGATG
CATTCTTAGCTGAATTAAAAGAACAATTTAGCCAAGTGCGTGTCGGTAATCCAAGAGAAGATGGTACACAAGTAGGCCCT
ATCATTAGTAAAAAACAATTTGATCAAGTACAAAATTATATTAATAAAGGTATTGAAGAAGGTGCTGAATTATTTTATGG
TGGTCCTGGTAAACCAGAAGGACTTGAAAAAGGATACTTTGCACGTCCGACAATTTTTATTAATGTAGATAATCAAATGA
CGATAGCACAAGAAGAAATTTTTGGGCCAGTAATGTCAGTTATCACTTATAACGATTTAGATGAAGCGATTCAAATTGCA
AATGATACAAAATATGGTTTAGCAGGATATGTTATTGGTAAGGACAAAGAAACATTGCATAAAGTAGCTCGTTCTATTGA
AGCAGGTACAGTAGAAATAAACGAAGCAGGTAGAAAGCCAGACTTACCATTTGGTGGCTATAAACAATCTGGTTTAGGTC
GTGAATGGGGCGATTATGGTATTGAAGAGTTCTTAGAAGTGAAATCTATAGCTGGCTATTTTAAATAA

Protein sequence :
MRDYTKQYINGEWVESNSNETIEVINPATEEVIGKVAKGNKADVDKAVEAADNVYLEFRHTSVKERQALLDKIVKEYENR
KDDIVQAITDELGAPLSLSERVHYQMGLNHFVAARDALDNYEFEERRGDDLVVKEAIGVSGLITPWNFPTNQTSLKLAAA
FAAGSPVVLKPSEETPFAAVILAEIFDKVGVPKGVFNLVNGDGAGVGNPLSEHPKVRMMSFTGSGPTGSKIMEKAAKDFK
KVSLELGGKSPYIVLDDVDIKEAAKATTGKVVNNTGQVCTAGTRVLVPNKIKDAFLAELKEQFSQVRVGNPREDGTQVGP
IISKKQFDQVQNYINKGIEEGAELFYGGPGKPEGLEKGYFARPTIFINVDNQMTIAQEEIFGPVMSVITYNDLDEAIQIA
NDTKYGLAGYVIGKDKETLHKVARSIEAGTVEINEAGRKPDLPFGGYKQSGLGREWGDYGIEEFLEVKSIAGYFK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-48 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SAR2210 YP_041570.1 aldehyde dehydrogenase VFG0082 Protein 2e-48 42