Gene Information

Name : kdpD (SAR2166)
Accession : YP_041528.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : sensor kinase
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2205
EC number : 2.7.3.-
Position : 2235309 - 2237966 bp
Length : 2658 bp
Strand : +
Note : Two-component regulatory system family, sensor kinase. Similar to Escherichia coli sensor for high-affinity potassium transport system KdpD SW:KDPD_ECOLI (P21865) (894 aa) fasta scores: E(): 4.1e-61, 26.59% id in 876 aa, and to Rhizobium loti two-componen

DNA sequence :
ATGTCAAACACTGAATCGCTAAACATAGGAAAAAAGCGTGGATCTTTAACAATTTACATCGGTTACAGTCCAGGTGTTGG
TAAAACATTTGAGATGCTTTCAAATGCCATTGAACTATTTCAAAGTAACGTTGATATTAAACTAGGATATATTGAACCGC
ATCAACGTGATGAAACAAATGCATTAGCTGAACAATTACCTAAAATCGCAACCAATTTTACTAAACATGGTAGTCATCAT
TTTCAATATTTAGATGTCGACCGCATAATCGAAGAATCGCCGACAATAGTACTTATCGATGAGTTAGCACATACGAACAT
TTCTAGAGATCGTCATGAGAAACGATATATGGATATTGAAGAAATTTTAAATCATGGTATCGATGTTCATACTACTTTGA
ACATTCAACATATTGAAAGTTTAAGTAGTCAAATTGAACTGATGACCGGTGTACATGTTAAAGAACGTGTACCCGACTAT
TTCATAATGAGCGCCGATGTATTAGAAGTCGTAGATATCTCACCTGAACAATTAATTAAACGCTTAAAAGCTGGCAAGGT
ATATAAAAAGGATAGGCTAGATGTAGCATTTAGTAATTTCTTTACGTATGCCCACCTAAGCGAACTGCGTACATTGACGT
TAAGAACAGTTGCCGACTTGATGAGTGATAAAGAAAAAGTCCGACACAATCATAAAACGTCACTCAAACCTCATATTGCT
GTGGCAATTAGTGGGAGTATTTATAATGAAGCAGTAATTAAAGAGGCATTCCATATTGCTCAAAAAGAACATGCAAAATT
CACTGCTATTTATATAGATGTATTCGAAAAAAGCAGGCAATATAAAGATAGTCAAAAGCAAGTGCATCAACATCTCATGC
TTGCAAAATCTTTAGGAGCAAAAGTAAAAGTAGTTTATAGCCAAACCGTTGCATTAGGATTAGACGAATGGTGTAAAAAT
CAAGATGTAACCAAATTAATTATCGGACAACATATTAGAAATAAGCGGCGAGACTTTTTCAATAAACCTTTAATTGACCA
TTTAATGTCCTTTGAACATAGCTATAAAATCGAAATCGTTCCAATCAAACAAATACCTGTTGAATTGAAAATGAACAAAT
CACCCTATCGTCCTAAAGGCAAACGGTTCGCCATAGATATGTTAAAAATGATTCTGATTCAAATAATTTGTGTAATGATG
GGACTGTGGATTTATCAACTTGATAAGCATGAGTCTAGTACGATTATTTTAATGATTTTTCTCATCGGCATCATTTTGTT
ATCCATTTGGACGCGGTCCTACATCATTGGCTTTTTAGCAGCAATTATTAACGTATTTGTTTTTAATTATTTTTTTACGG
AACCTAGATATACATTTGAAGTATACCGCTTTGACTATCCTATTACATTTATCGTCAGCATTTTAACAAGTATTTTAACG
AGTGCTTTATTAAAACAAATTAAATTCCAATACGCCATTACTAAAAAGCAACTTTATCGTACAGATTTATTATTTCAATT
TAATGATTCGATTAAACAAACTTATACAGTTGAAAACTTACTAATAAATGCTGGATACCAAATTAATCAATTATTGCAAC
AATCAATTACTATATACGTTATCAATCAATCCAAAGTAATTAAAACAATACCATTGCAAAACCATATCGATAATAAGACT
CAACAGCATGAACAAGCATTAAGCTGGGTAATTAAAAATGAAAGACAAGCTGGTGCAACAACAGATACATTTCCAGGCAT
TAATAAATGGTTGATACCAATTGGCACATCTCCGATTAAAGGCATTCTAGCCATTGATTACCAAAGTTCTCAAGTGATTA
ATCCATATGATGCATCAATATTAGAATCAATGTTAAATGAACTTTCTCTCGCCGTTGAAAATGTGACGTTGCTTAAACAA
ACAAGAGAATCCATGTTACAGGCTGAACGTCAACTGACACATTCAAATTTTTTAAGATCAATTTCGCATGACATACGTAC
ACCGTTAACAACAATTATGGGAAATTTAGATATTTTAGTGTCACATAGTAAAGATATGTCTATCATAGAAAAGGAACAAT
TACTTGTGCATAGTTTTCAAGAAAGTCAGTATTTATATCTATTAGTGACAAATATTTTATCATTAACAAAATTACAGTCA
TCAAATGTTCAGATAAAATTGCAACCTTATCTCGTTAGTGAATTAGTAGAAGAAATCGATATGATTTTAGAACGTCGCCA
TTTAAAAAAGCGTATAACTGTATCATCCTCAGTAGATTTACAGTTTATACACATTGACAGTAAGTTGATTTTACAAGCTT
TATTCAATTTGATTGAAAATGCAGTTAAACACACTTCTACTGACACCAAAATCAATTTATCTATTCGTTATGCTAGCGAT
GAACAAATCGAATTTGCTGTTATAGACGAAGGACCTGGAATTAGTATAGAAGAACAACAAAAGATATTCGAGCCTTTTTA
CACAGGGTCAAATAAATATTTTAAAGATAACCAAAAAGAAAGCATGGGACTAGGCTTATATTTAGTACAGACTATCCTAC
ACAAACATCAATCAAACCTACAATATAAACCGAACCAACCACATGGCAGTATATTCTATTTCAATATAGATACAGACTTT
AATGAAGGAGACATATAA

Protein sequence :
MSNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNVDIKLGYIEPHQRDETNALAEQLPKIATNFTKHGSHH
FQYLDVDRIIEESPTIVLIDELAHTNISRDRHEKRYMDIEEILNHGIDVHTTLNIQHIESLSSQIELMTGVHVKERVPDY
FIMSADVLEVVDISPEQLIKRLKAGKVYKKDRLDVAFSNFFTYAHLSELRTLTLRTVADLMSDKEKVRHNHKTSLKPHIA
VAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEKSRQYKDSQKQVHQHLMLAKSLGAKVKVVYSQTVALGLDEWCKN
QDVTKLIIGQHIRNKRRDFFNKPLIDHLMSFEHSYKIEIVPIKQIPVELKMNKSPYRPKGKRFAIDMLKMILIQIICVMM
GLWIYQLDKHESSTIILMIFLIGIILLSIWTRSYIIGFLAAIINVFVFNYFFTEPRYTFEVYRFDYPITFIVSILTSILT
SALLKQIKFQYAITKKQLYRTDLLFQFNDSIKQTYTVENLLINAGYQINQLLQQSITIYVINQSKVIKTIPLQNHIDNKT
QQHEQALSWVIKNERQAGATTDTFPGINKWLIPIGTSPIKGILAIDYQSSQVINPYDASILESMLNELSLAVENVTLLKQ
TRESMLQAERQLTHSNFLRSISHDIRTPLTTIMGNLDILVSHSKDMSIIEKEQLLVHSFQESQYLYLLVTNILSLTKLQS
SNVQIKLQPYLVSELVEEIDMILERRHLKKRITVSSSVDLQFIHIDSKLILQALFNLIENAVKHTSTDTKINLSIRYASD
EQIEFAVIDEGPGISIEEQQKIFEPFYTGSNKYFKDNQKESMGLGLYLVQTILHKHQSNLQYKPNQPHGSIFYFNIDTDF
NEGDI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kdpD NP_370595.1 sensor protein KdpD Not tested Type-II SCCmec Protein 0.0 59
kdpD NP_373307.1 hypothetical protein Not tested Type-II SCCmec Protein 0.0 59
kdpD YP_190032.1 sensor histidine kinase KdpD Not tested Type-II SCCmec Protein 0.0 59
SH0032 YP_251947.1 hypothetical protein Not tested SCCmec Protein 0.0 59
SAR0069 YP_039537.1 sensor kinase Not tested Type-II SCCmec Protein 0.0 59