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Name : kdpD (SAR2166) Accession : YP_041528.1 Strain : Staphylococcus aureus MRSA252 Genome accession: NC_002952 Putative virulence/resistance : Unknown Product : sensor kinase Function : - COG functional category : T : Signal transduction mechanisms COG ID : COG2205 EC number : 2.7.3.- Position : 2235309 - 2237966 bp Length : 2658 bp Strand : + Note : Two-component regulatory system family, sensor kinase. Similar to Escherichia coli sensor for high-affinity potassium transport system KdpD SW:KDPD_ECOLI (P21865) (894 aa) fasta scores: E(): 4.1e-61, 26.59% id in 876 aa, and to Rhizobium loti two-componen DNA sequence : ATGTCAAACACTGAATCGCTAAACATAGGAAAAAAGCGTGGATCTTTAACAATTTACATCGGTTACAGTCCAGGTGTTGG TAAAACATTTGAGATGCTTTCAAATGCCATTGAACTATTTCAAAGTAACGTTGATATTAAACTAGGATATATTGAACCGC ATCAACGTGATGAAACAAATGCATTAGCTGAACAATTACCTAAAATCGCAACCAATTTTACTAAACATGGTAGTCATCAT TTTCAATATTTAGATGTCGACCGCATAATCGAAGAATCGCCGACAATAGTACTTATCGATGAGTTAGCACATACGAACAT TTCTAGAGATCGTCATGAGAAACGATATATGGATATTGAAGAAATTTTAAATCATGGTATCGATGTTCATACTACTTTGA ACATTCAACATATTGAAAGTTTAAGTAGTCAAATTGAACTGATGACCGGTGTACATGTTAAAGAACGTGTACCCGACTAT TTCATAATGAGCGCCGATGTATTAGAAGTCGTAGATATCTCACCTGAACAATTAATTAAACGCTTAAAAGCTGGCAAGGT ATATAAAAAGGATAGGCTAGATGTAGCATTTAGTAATTTCTTTACGTATGCCCACCTAAGCGAACTGCGTACATTGACGT TAAGAACAGTTGCCGACTTGATGAGTGATAAAGAAAAAGTCCGACACAATCATAAAACGTCACTCAAACCTCATATTGCT GTGGCAATTAGTGGGAGTATTTATAATGAAGCAGTAATTAAAGAGGCATTCCATATTGCTCAAAAAGAACATGCAAAATT CACTGCTATTTATATAGATGTATTCGAAAAAAGCAGGCAATATAAAGATAGTCAAAAGCAAGTGCATCAACATCTCATGC TTGCAAAATCTTTAGGAGCAAAAGTAAAAGTAGTTTATAGCCAAACCGTTGCATTAGGATTAGACGAATGGTGTAAAAAT CAAGATGTAACCAAATTAATTATCGGACAACATATTAGAAATAAGCGGCGAGACTTTTTCAATAAACCTTTAATTGACCA TTTAATGTCCTTTGAACATAGCTATAAAATCGAAATCGTTCCAATCAAACAAATACCTGTTGAATTGAAAATGAACAAAT CACCCTATCGTCCTAAAGGCAAACGGTTCGCCATAGATATGTTAAAAATGATTCTGATTCAAATAATTTGTGTAATGATG GGACTGTGGATTTATCAACTTGATAAGCATGAGTCTAGTACGATTATTTTAATGATTTTTCTCATCGGCATCATTTTGTT ATCCATTTGGACGCGGTCCTACATCATTGGCTTTTTAGCAGCAATTATTAACGTATTTGTTTTTAATTATTTTTTTACGG AACCTAGATATACATTTGAAGTATACCGCTTTGACTATCCTATTACATTTATCGTCAGCATTTTAACAAGTATTTTAACG AGTGCTTTATTAAAACAAATTAAATTCCAATACGCCATTACTAAAAAGCAACTTTATCGTACAGATTTATTATTTCAATT TAATGATTCGATTAAACAAACTTATACAGTTGAAAACTTACTAATAAATGCTGGATACCAAATTAATCAATTATTGCAAC AATCAATTACTATATACGTTATCAATCAATCCAAAGTAATTAAAACAATACCATTGCAAAACCATATCGATAATAAGACT CAACAGCATGAACAAGCATTAAGCTGGGTAATTAAAAATGAAAGACAAGCTGGTGCAACAACAGATACATTTCCAGGCAT TAATAAATGGTTGATACCAATTGGCACATCTCCGATTAAAGGCATTCTAGCCATTGATTACCAAAGTTCTCAAGTGATTA ATCCATATGATGCATCAATATTAGAATCAATGTTAAATGAACTTTCTCTCGCCGTTGAAAATGTGACGTTGCTTAAACAA ACAAGAGAATCCATGTTACAGGCTGAACGTCAACTGACACATTCAAATTTTTTAAGATCAATTTCGCATGACATACGTAC ACCGTTAACAACAATTATGGGAAATTTAGATATTTTAGTGTCACATAGTAAAGATATGTCTATCATAGAAAAGGAACAAT TACTTGTGCATAGTTTTCAAGAAAGTCAGTATTTATATCTATTAGTGACAAATATTTTATCATTAACAAAATTACAGTCA TCAAATGTTCAGATAAAATTGCAACCTTATCTCGTTAGTGAATTAGTAGAAGAAATCGATATGATTTTAGAACGTCGCCA TTTAAAAAAGCGTATAACTGTATCATCCTCAGTAGATTTACAGTTTATACACATTGACAGTAAGTTGATTTTACAAGCTT TATTCAATTTGATTGAAAATGCAGTTAAACACACTTCTACTGACACCAAAATCAATTTATCTATTCGTTATGCTAGCGAT GAACAAATCGAATTTGCTGTTATAGACGAAGGACCTGGAATTAGTATAGAAGAACAACAAAAGATATTCGAGCCTTTTTA CACAGGGTCAAATAAATATTTTAAAGATAACCAAAAAGAAAGCATGGGACTAGGCTTATATTTAGTACAGACTATCCTAC ACAAACATCAATCAAACCTACAATATAAACCGAACCAACCACATGGCAGTATATTCTATTTCAATATAGATACAGACTTT AATGAAGGAGACATATAA Protein sequence : MSNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNVDIKLGYIEPHQRDETNALAEQLPKIATNFTKHGSHH FQYLDVDRIIEESPTIVLIDELAHTNISRDRHEKRYMDIEEILNHGIDVHTTLNIQHIESLSSQIELMTGVHVKERVPDY FIMSADVLEVVDISPEQLIKRLKAGKVYKKDRLDVAFSNFFTYAHLSELRTLTLRTVADLMSDKEKVRHNHKTSLKPHIA VAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEKSRQYKDSQKQVHQHLMLAKSLGAKVKVVYSQTVALGLDEWCKN QDVTKLIIGQHIRNKRRDFFNKPLIDHLMSFEHSYKIEIVPIKQIPVELKMNKSPYRPKGKRFAIDMLKMILIQIICVMM GLWIYQLDKHESSTIILMIFLIGIILLSIWTRSYIIGFLAAIINVFVFNYFFTEPRYTFEVYRFDYPITFIVSILTSILT SALLKQIKFQYAITKKQLYRTDLLFQFNDSIKQTYTVENLLINAGYQINQLLQQSITIYVINQSKVIKTIPLQNHIDNKT QQHEQALSWVIKNERQAGATTDTFPGINKWLIPIGTSPIKGILAIDYQSSQVINPYDASILESMLNELSLAVENVTLLKQ TRESMLQAERQLTHSNFLRSISHDIRTPLTTIMGNLDILVSHSKDMSIIEKEQLLVHSFQESQYLYLLVTNILSLTKLQS SNVQIKLQPYLVSELVEEIDMILERRHLKKRITVSSSVDLQFIHIDSKLILQALFNLIENAVKHTSTDTKINLSIRYASD EQIEFAVIDEGPGISIEEQQKIFEPFYTGSNKYFKDNQKESMGLGLYLVQTILHKHQSNLQYKPNQPHGSIFYFNIDTDF NEGDI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| kdpD | NP_370595.1 | sensor protein KdpD | Not tested | Type-II SCCmec | Protein | 0.0 | 59 |
| kdpD | NP_373307.1 | hypothetical protein | Not tested | Type-II SCCmec | Protein | 0.0 | 59 |
| SH0032 | YP_251947.1 | hypothetical protein | Not tested | SCCmec | Protein | 0.0 | 59 |
| kdpD | YP_190032.1 | sensor histidine kinase KdpD | Not tested | Type-II SCCmec | Protein | 0.0 | 59 |
| SAR0069 | YP_039537.1 | sensor kinase | Not tested | Type-II SCCmec | Protein | 0.0 | 59 |
