Gene Information

Name : SAR2109 (SAR2109)
Accession : YP_041474.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : succinyl-diaminopimelate desuccinylase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0624
EC number : -
Position : 2172100 - 2173323 bp
Length : 1224 bp
Strand : +
Note : dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is simi

DNA sequence :
ATGACAACTTTTAGTGAAAAAGAAAAAATTCAATTACTAGCAGATATTGTTGAACTACAAACTGAAAATAATAATGAAAT
AGACGTTTGTAATTATTTAAAAGATTTATTCGACAAGTACGATATTAAATCTGAAATTTTGAAAGTTAATGAACACCGCG
CCAATTTCGTTGCAGAAATCGGTAGTGGCTCTCCCATACTTGCATTGAGCGGTCATATGGATGTTGTTGATGCAGGAAAT
CAAGATAATTGGACTTATCCCCCTTTTCAACTCACAGAAAAAGATGACAAATTATATGGTCGAGGCACAACAGATATGAA
AGGCGGTCTGATGGCTTTGGTCATCGCACTCATTGAATTAAAAGAACAAAACCAATTACCTCAAGGAACCATTAGATTAC
TCGCTACTGCTGGTGAAGAGAAAGAACAAGAAGGCGCCAAATTATTAGCAGATAAAGGCTATTTAGATGATGTTGATGGT
CTAATGATTGCTGAACCAACTGGATCTGGAATTTATTATGCACATAAAGGGTCTATGTCATGTAAAGTAACTGCAACTGG
TAAAGCTGTCCATAGCTCAGTTCCATTTATTGGTGACAATGCAATTGATACACTGCTTGAATTTTATAATCAATTTAAAG
AAAAATATGCAGAGCTTAAAAAAAATGATACTAAACATGAGTTAGATGTTGCTCCCATGTTCAAATCATTGATAGGAAAA
GATATTTCTGAAGAGGATGCAAATTATGCATCTGGTCTTACAGCTGTATGTTCGATTATAAATGGCGGTAAACAATTTAA
CTCTGTACCAGATGAAGCTTCACTTGAATTTAACGTAAGACCAGTTCCTGAGTATGATAACGACTTTATAGAATCGTTTT
TCCAAAATATCATTAATAATGTGGATAGCAATAAGCTTTCACTCGATATTCCAAGCAACCATCGACCTGTAACAAGCGAT
AAAAATAGCAAATTAATTACTACGATTAAAGATGTAGCTTCTAGTTATGTAGACAAAGACGATATATTTGTTTCGGCGCT
TGTAGGTGCAACGGATGCTTCCAGCTTCTTAGGAGATAATAAGGACAATGTTGATTTAGCCATTTTTGGACCAGGTAATC
CATTAATGGCACATCAAATCGATGAATATATTGAAAAAGATATGTATCTGAAATATATTGATATTTTCAAAGAGGCTTCC
ATTCAATATTTAAAGGAGAAATAA

Protein sequence :
MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANFVAEIGSGSPILALSGHMDVVDAGN
QDNWTYPPFQLTEKDDKLYGRGTTDMKGGLMALVIALIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDG
LMIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYAELKKNDTKHELDVAPMFKSLIGK
DISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINNVDSNKLSLDIPSNHRPVTSD
KNSKLITTIKDVASSYVDKDDIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEAS
IQYLKEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dapE CAA07459.1 succinyl-diaminopimelate desuccinylase Not tested Internalin Protein 9e-66 44
unnamed CAC20637.1 - Not tested Internalin Protein 2e-65 43