Gene Information

Name : sak (SAR2039)
Accession : YP_041410.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Virulence
Product : staphylokinase precursor
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2128315 - 2128806 bp
Length : 492 bp
Strand : -
Note : Highly similar to Staphylococcus aureus plasminogen activator staphylokinase precursor Sak SW:SAK_STAAU (P00802) (163 aa) fasta scores: E(): 9.5e-61, 98.77% id in 163 aa, and to bacteriophage P42D staphylokinase precursor Sak SW:SAK_BPP42 (P15240) (163 aa

DNA sequence : 
ATGCTCAAAAGAGGTTTATTATTTTTAACTGTTTTATTGTTATTATTCTCATTTTCTTCAATTACTAATGAGGTAAGTGC
ATCAAGTTCATTCGACAAAGGAAAATATAAAAAAGGCGATGACGCGAGTTATTTTGAACCAACAGGCCCGTATTTGATGG
TAAATGTGACTGGAGTTGATGGTAAAGGAAATGAATTGCTATCCCCTCATTATGTCGAGTTTCCTATTAAACCTGGGACT
ACACTTACAAAAGAAAAAATTGAATACTATGTCGAATGGGCATTAGATGCGACAGCATATAAAGAGTTTAGAGTAGTTGA
ATTAGATCCAAGCGCAAAGATCGAAGTCACTTATTATGATAAGAATAAGAAAAAAGAAGAAACGAAGTCTTTCCCTATAA
CAGAAAAAGGTTTTGTTGTCCCAGATTTATCAGAGCATATTAAAAACCCTGGATTCAACTTAATTACAAAGGTTATTATA
GAAAAGAAATAA

Protein sequence : 
MLKRGLLFLTVLLLLFSFSSITNEVSASSSFDKGKYKKGDDASYFEPTGPYLMVNVTGVDGKGNELLSPHYVEFPIKPGT
TLTKEKIEYYVEWALDATAYKEFRVVELDPSAKIEVTYYDKNKKKEETKSFPITEKGFVVPDLSEHIKNPGFNLITKVII
EKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sak YP_494573.1 staphylokinase Virulence ¥ÕSa3 Protein 2e-62 100
sak YP_494573.1 staphylokinase Virulence ¥ÕSa3 Protein 2e-62 100
sak NP_646702.1 staphylokinase precursor Virulence ¥ÕSa3 Protein 2e-61 99
sak NP_375053.1 staphylokinase Virulence ¥ÕSa3 Protein 1e-61 99
sak NP_372468.1 staphylokinase Virulence ¥ÕSa3 Protein 6e-62 99
SAKOR_01923 YP_008492111.1 Staphylokinase precursor Not tested ¥ÕSa3 Protein 5e-62 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sak YP_041410.1 staphylokinase precursor VFG1328 Protein 6e-62 99