Gene Information

Name : nadE (SAR2005)
Accession : YP_041378.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : NAD synthetase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0171
EC number : 6.3.1.5
Position : 2096457 - 2097278 bp
Length : 822 bp
Strand : -
Note : catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli

DNA sequence :
ATGAGTAAATTACAAGACGTTATTGTACAAGAAATGAAAGTGAAAAAGCGTATCGACAGTGCGGAAGAAATTGCTGAGTT
AAAACAATTTATAAAAAGTTATGTCCAATCACATTCATTTATAAAATCTTTAGTGTTAGGTATTTCAGGAGGACAAGATT
CTACATTAGTTGGAAAATTAGTGCAAATGTCTGTTAACGAATTACGTGAAGAAGGCATTGATTGTACGTTTATTGCAGTT
AAATTACCTTATGGAGTTCAAAAAGATGCTGATGAAGTTGAGCAAGCTTTACAATTCATTGAGCCAGATGAAATAGTAAC
AGTCAATATTAAGCCTGCAGTTGATCAAAGTGTGCAATCATTGAAAGAAGCTGGGATTGTCCTAACAGACTTCCAAAAAG
GTAATGAAAAGGCTCGCGAACGTATGAAAGTACAATTTTCAATTGCTTCAAACCGACAAGGTATTGTAGTAGGAACAGAT
CATTCAGCTGAAAATATAACTGGTTTTTATACGAAATATGGTGATGGTGCTGCAGATATTGCACCTATATTCGGTTTGAA
TAAGCGCCAAGGTCGTCAGTTATTAGCTTATCTTGGTGCACCAAAACAATTGTATGAAAAAACACCAACTGCTGATTTAG
AAGATGACAAACCACAGCTTCCAGATGAAGATGCATTAGGTGTAACTTATGAGGCGATTGATAATTATTTAGAAGGTAAG
CCAGTTACGCCAGAAGAACAAAAAGTAATTGAAAATCATTATATACGGAATGCACACAAACGTGAACTTGCATATACAAG
ATACACGTGGCCAAAATCCTAA

Protein sequence :
MSKLQDVIVQEMKVKKRIDSAEEIAELKQFIKSYVQSHSFIKSLVLGISGGQDSTLVGKLVQMSVNELREEGIDCTFIAV
KLPYGVQKDADEVEQALQFIEPDEIVTVNIKPAVDQSVQSLKEAGIVLTDFQKGNEKARERMKVQFSIASNRQGIVVGTD
HSAENITGFYTKYGDGAADIAPIFGLNKRQGRQLLAYLGAPKQLYEKTPTADLEDDKPQLPDEDALGVTYEAIDNYLEGK
PVTPEEQKVIENHYIRNAHKRELAYTRYTWPKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadE YP_001800880.1 NAD synthetase Not tested Not named Protein 8e-58 50