Gene Information

Name : splC (SAR1906)
Accession : YP_041284.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Virulence
Product : serine protease
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG3591
EC number : -
Position : 1989259 - 1989978 bp
Length : 720 bp
Strand : -
Note : Similar to Staphylococcus aureus serine protease SplC TR:Q9KH49 (EMBL:AF271715) (239 aa) fasta scores: E(): 7.6e-83, 94.56% id in 239 aa

DNA sequence :
ATGAATAAAAATTTAGTCATTAAAAGCATGGCAGCATTAGCCATTTTAACATCAGTAACTGGAATAAGTGCTGCAGTCGT
TGAAGAGACACAACAAATAGCAAAAGCAGAGAAGCATGTTACGCAAGTTAAAGATACAAATGTTTTTCCGTATCATGGCG
TCGTTGCATTTAAAGATGCGACAGGCTTTGTAATCGGTAAAAATACAATTATCACTAATAAACATGTATCAAAGGATTAT
AAAGTTGGCGATAGAATTACTGCTCATCCAAATGGTGACAAAGGAAATGGTGGTATTTATAAAATTAAAAGTATTTCCGA
TTATCCAGGCAATGAAGATATTTCCGTCATGAATATAGAAGAACAAGCGGTTGAACGTGGATCCAATGGCTTTAATTTTA
ATGATAATGTTCAAGCATTTAAATTTGCAAAAGATGCTAAAGTTGATGACAAAATTAAAGTTATCGGTTACCCGTTACCT
GCACAAAACAGTTTTAAACAATTTGAATCTACAGGAACTATAAAACGAATTAAAGACAATATTTTAAATTTTGATGCATA
TATCGAACCAGGTAATTCAGGATCACCCGTTCTAAATTCTAACAATGAAGTCATAGGTGTTGTATATGGCGGCATTGGAA
AAGTTGGTTCTGAATACAATGGTGCTGTATATTTTACGCCTCAAATTAAAGATTTTATTCAAAAGCACATTGAACAATAA

Protein sequence :
MNKNLVIKSMAALAILTSVTGISAAVVEETQQIAKAEKHVTQVKDTNVFPYHGVVAFKDATGFVIGKNTIITNKHVSKDY
KVGDRITAHPNGDKGNGGIYKIKSISDYPGNEDISVMNIEEQAVERGSNGFNFNDNVQAFKFAKDAKVDDKIKVIGYPLP
AQNSFKQFESTGTIKRIKDNILNFDAYIEPGNSGSPVLNSNNEVIGVVYGGIGKVGSEYNGAVYFTPQIKDFIQKHIEQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
splC YP_041284.1 serine protease Virulence vSa¥â Protein 9e-88 100
splC YP_494447.1 serine protease SplC Virulence vSa¥â Protein 4e-85 95
splC NP_372335.1 serine protease Virulence vSa¥â Protein 1e-84 95
splC NP_374918.1 serine protease SplC Virulence vSa¥â Protein 1e-84 95
splC YP_186695.1 serine protease SplC Virulence vSa¥â Protein 4e-85 95
splC YP_001332738.1 serine protease SplC Virulence vSa¥â Protein 4e-85 95
SAKOR_01759 YP_008491947.1 Serine protease splC Virulence vSa¥â Protein 4e-85 95
splC NP_646570.1 serine protease SplC Virulence vSa¥â Protein 2e-85 94
SAS1734 YP_043850.1 serine protease Virulence vSa¥â Protein 5e-85 94
splB YP_186696.1 serine protease SplB Virulence vSa¥â Protein 7e-59 63
splB YP_001332739.1 serine protease SplB Virulence vSa¥â Protein 7e-59 63
splB YP_494448.1 serine protease SplB Virulence vSa¥â Protein 7e-59 63
SAS1735 YP_043851.1 serine protease Virulence vSa¥â Protein 1e-58 63
splB NP_646571.1 serine protease SplB Virulence vSa¥â Protein 1e-58 63
SAKOR_01760 YP_008491948.1 Serine protease splB Virulence vSa¥â Protein 2e-58 63
splB NP_372336.1 serine protease Virulence vSa¥â Protein 3e-58 62
splB NP_374919.1 serine protease SplB Virulence vSa¥â Protein 3e-58 62
splA YP_494449.1 serine protease SplA Virulence vSa¥â Protein 9e-36 51
splF NP_372333.1 serine protease Virulence vSa¥â Protein 2e-40 51
splF NP_374916.1 serine protease SplF Virulence vSa¥â Protein 2e-40 51
SAS1733 YP_043849.1 serine protease Virulence vSa¥â Protein 2e-40 51
splF NP_646569.1 serine protease SplF Virulence vSa¥â Protein 2e-40 51
SACOL1864 YP_186692.1 serine protease SplF Virulence vSa¥â Protein 3e-40 51
splF YP_001332735.1 serine protease SplF Virulence vSa¥â Protein 3e-40 51
splA NP_374920.1 serine protease SplA Virulence vSa¥â Protein 4e-41 50
SAS1736 YP_043852.1 serine protease Virulence vSa¥â Protein 4e-35 50
splA NP_646572.1 serine protease SplA Virulence vSa¥â Protein 4e-35 50
SAKOR_01761 YP_008491949.1 Serine protease splA Virulence vSa¥â Protein 3e-42 50
splA NP_372337.1 serine protease Virulence vSa¥â Protein 4e-41 50
splA YP_186697.1 serine protease SplA Virulence vSa¥â Protein 2e-35 50
splA YP_001332740.1 serine protease SplA Virulence vSa¥â Protein 2e-35 50
splF YP_494444.1 serine protease SplF Virulence vSa¥â Protein 4e-40 50
SACOL1865 YP_186693.1 serine protease SplE Virulence vSa¥â Protein 5e-41 50
splE YP_001332736.1 serine protease SplE Virulence vSa¥â Protein 5e-41 50
splE YP_494445.1 serine protease SplE Virulence vSa¥â Protein 5e-41 50
splD NP_372334.1 serine protease Virulence vSa¥â Protein 6e-39 49
splD NP_374917.1 serine protease SplD Virulence vSa¥â Protein 6e-39 49
splD YP_001332737.1 serine protease SplD Virulence vSa¥â Protein 6e-39 49
splD YP_494446.1 serine protease SplD Virulence vSa¥â Protein 6e-39 49
SACOL1866 YP_186694.1 serine protease SplD Virulence vSa¥â Protein 7e-39 49
splE YP_041282.1 serine protease Virulence vSa¥â Protein 4e-41 49
SAKOR_01758 YP_008491946.1 Serine protease splD Virulence vSa¥â Protein 3e-39 49
SAR1905 YP_041283.1 serine protease Virulence vSa¥â Protein 2e-38 45