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Name : splE (SAR1902) Accession : YP_041282.1 Strain : Staphylococcus aureus MRSA252 Genome accession: NC_002952 Putative virulence/resistance : Virulence Product : serine protease Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG3591 EC number : - Position : 1986657 - 1987373 bp Length : 717 bp Strand : - Note : Similar to Staphylococcus aureus serine protease SplE TR:Q9KH47 (EMBL:AF271715) (238 aa) fasta scores: E(): 1.9e-85, 97.05% id in 238 aa. Simlar to SAR1905, 63.445% identity (63.445% ungapped) in 238 aa overlap, SAR1900, 64.481% identity (64.835% ungapped DNA sequence : ATGAATAAAAATATAATCATCAAAAGTATAGCAGCATTGACGATTTTAACATCAGTGACTGGTGTTGGCACAACAATGGT TGAAGGTATTCAACAAACAGCCAAAGCCGAACATAATGTGAAACTAATCAAAAATACTAATGTAGCACCATACAATGGTA TCGTTTCGATAGGATCTGGAACAGGTTTCATTGTCGGAAAAAATACAATTGTTACTAACAAGCATGTCGTTGCAGGTATG GAAATTGGCGCACATATTATTGCGCATCCTAATGGTGAATATAATAATGGCGGTTTTTATAAAGTTAAAAAAATTGTCCG TTATGCAGGTAAAGAAGATATTGCCATTCTACATGTGGAAGATAAAGCTGTTCATCCAAAAAATAGGAATTTTAAAGATT ATACAGGTATTTTAAAAATAGCATCAGAAGCCAAAGAAAATGAACGCATTTCAATTGTTGGCTATCCAGAACCTTATATA AATAAATTTCAAATGTATGAATCAACAGGAAAAGTGCTATCAGTGAAAGGCAACATGATTATTTCTGATGCTTTCGTAGA ACCAGGCAACTCAGGTTCAGCTGTATTTAATAGTAAATACGAAGTTGTAGGTGTTCACTTTGGTGGAAACGGCCCTGCAA ATAAAAGTACAAAAGGATATGGCGTTTATTTCTCTCCTGAAATTAAGAAATTCATCGCAGATAATTTAGATAAATAA Protein sequence : MNKNIIIKSIAALTILTSVTGVGTTMVEGIQQTAKAEHNVKLIKNTNVAPYNGIVSIGSGTGFIVGKNTIVTNKHVVAGM EIGAHIIAHPNGEYNNGGFYKVKKIVRYAGKEDIAILHVEDKAVHPKNRNFKDYTGILKIASEAKENERISIVGYPEPYI NKFQMYESTGKVLSVKGNMIISDAFVEPGNSGSAVFNSKYEVVGVHFGGNGPANKSTKGYGVYFSPEIKKFIADNLDK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| splE | YP_041282.1 | serine protease | Virulence | vSa¥â | Protein | 2e-106 | 100 |
| splE | YP_001332736.1 | serine protease SplE | Virulence | vSa¥â | Protein | 3e-104 | 98 |
| splE | YP_494445.1 | serine protease SplE | Virulence | vSa¥â | Protein | 3e-104 | 98 |
| SACOL1865 | YP_186693.1 | serine protease SplE | Virulence | vSa¥â | Protein | 3e-104 | 98 |
| SACOL1864 | YP_186692.1 | serine protease SplF | Virulence | vSa¥â | Protein | 4e-75 | 70 |
| splF | YP_001332735.1 | serine protease SplF | Virulence | vSa¥â | Protein | 4e-75 | 70 |
| splF | NP_372333.1 | serine protease | Virulence | vSa¥â | Protein | 3e-75 | 70 |
| splF | NP_374916.1 | serine protease SplF | Virulence | vSa¥â | Protein | 3e-75 | 70 |
| splF | NP_646569.1 | serine protease SplF | Virulence | vSa¥â | Protein | 2e-74 | 69 |
| splF | YP_494444.1 | serine protease SplF | Virulence | vSa¥â | Protein | 6e-75 | 69 |
| SAS1733 | YP_043849.1 | serine protease | Virulence | vSa¥â | Protein | 2e-74 | 69 |
| SACOL1866 | YP_186694.1 | serine protease SplD | Virulence | vSa¥â | Protein | 2e-74 | 68 |
| splD | NP_372334.1 | serine protease | Virulence | vSa¥â | Protein | 2e-74 | 68 |
| splD | NP_374917.1 | serine protease SplD | Virulence | vSa¥â | Protein | 2e-74 | 68 |
| splD | YP_001332737.1 | serine protease SplD | Virulence | vSa¥â | Protein | 2e-74 | 68 |
| splD | YP_494446.1 | serine protease SplD | Virulence | vSa¥â | Protein | 2e-74 | 68 |
| SAKOR_01758 | YP_008491946.1 | Serine protease splD | Virulence | vSa¥â | Protein | 2e-74 | 68 |
| SAR1905 | YP_041283.1 | serine protease | Virulence | vSa¥â | Protein | 2e-73 | 64 |
| splB | YP_494448.1 | serine protease SplB | Virulence | vSa¥â | Protein | 1e-61 | 57 |
| splB | YP_186696.1 | serine protease SplB | Virulence | vSa¥â | Protein | 1e-61 | 57 |
| splB | YP_001332739.1 | serine protease SplB | Virulence | vSa¥â | Protein | 1e-61 | 57 |
| SAS1735 | YP_043851.1 | serine protease | Virulence | vSa¥â | Protein | 4e-61 | 56 |
| splB | NP_646571.1 | serine protease SplB | Virulence | vSa¥â | Protein | 4e-61 | 56 |
| splB | NP_372336.1 | serine protease | Virulence | vSa¥â | Protein | 3e-61 | 56 |
| splB | NP_374919.1 | serine protease SplB | Virulence | vSa¥â | Protein | 3e-61 | 56 |
| SAKOR_01760 | YP_008491948.1 | Serine protease splB | Virulence | vSa¥â | Protein | 6e-61 | 56 |
| splC | NP_646570.1 | serine protease SplC | Virulence | vSa¥â | Protein | 2e-51 | 50 |
| splC | NP_372335.1 | serine protease | Virulence | vSa¥â | Protein | 3e-50 | 50 |
| splC | NP_374918.1 | serine protease SplC | Virulence | vSa¥â | Protein | 3e-50 | 50 |
| splC | YP_186695.1 | serine protease SplC | Virulence | vSa¥â | Protein | 1e-50 | 50 |
| splC | YP_001332738.1 | serine protease SplC | Virulence | vSa¥â | Protein | 1e-50 | 50 |
| splC | YP_494447.1 | serine protease SplC | Virulence | vSa¥â | Protein | 1e-50 | 50 |
| SAS1734 | YP_043850.1 | serine protease | Virulence | vSa¥â | Protein | 6e-51 | 50 |
| SAKOR_01759 | YP_008491947.1 | Serine protease splC | Virulence | vSa¥â | Protein | 1e-50 | 50 |
| splC | YP_041284.1 | serine protease | Virulence | vSa¥â | Protein | 7e-51 | 49 |
| splA | NP_372337.1 | serine protease | Virulence | vSa¥â | Protein | 2e-42 | 45 |
| splA | NP_374920.1 | serine protease SplA | Virulence | vSa¥â | Protein | 2e-42 | 45 |
| SAKOR_01761 | YP_008491949.1 | Serine protease splA | Virulence | vSa¥â | Protein | 7e-43 | 45 |
| SAS1736 | YP_043852.1 | serine protease | Virulence | vSa¥â | Protein | 8e-37 | 44 |
| splA | NP_646572.1 | serine protease SplA | Virulence | vSa¥â | Protein | 8e-37 | 44 |
| splA | YP_494449.1 | serine protease SplA | Virulence | vSa¥â | Protein | 2e-37 | 44 |
| splA | YP_186697.1 | serine protease SplA | Virulence | vSa¥â | Protein | 2e-37 | 44 |
| splA | YP_001332740.1 | serine protease SplA | Virulence | vSa¥â | Protein | 2e-37 | 44 |
