Gene Information

Name : arsB2 (SAR1856)
Accession : YP_041242.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Resistance
Product : arsenical pump membrane protein 2
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 1946500 - 1947792 bp
Length : 1293 bp
Strand : +
Note : Similar to Staphylococcus aureus arsenical pump membrane protein ArsB SW:ARSB_STAAU (P30329) (429 aa) fasta scores: E(): 1.1e-119, 79.953% id in 429 aa, and to Escherichia coli arsenical pump membrane protein ArsB SW:ARSB_ECOLI (P37310) (429 aa) fasta sco

DNA sequence :
ATGATGACAACTTTAGCGACATTCATTTTTCTAGTAACTTTATTATTTGTATTATGGCAACCTAAAGGCCTAGATATTGG
ATTTACTGCATTAGCAGGTGCCTTTATTGCTGTTATTACTGGTGTTGTAAGTTTTTCCGATGTTTTCGAAGTAACAGGTA
TAGTCTGGAATGCCACTTTAACTTTTGTATCAGTCATTCTTATTTCATTAATATTAGATAAAGTTGGATTATTCGAATGG
TCAGCTATTCACATGCTTCATGCTTCAAAAGGTAGTGGCCTAAAAATGTTCGTTTATATCATATTATTGGGTGCCGTGGT
TGCTGCATTTTTCGCAAATGATGGCGCAGCTTTAATCTTAACGCCCATTGTATTAGCAATGGTAAAAAATATAGGTTTTA
GTAAGCGGGCCATATTTCCATTTATTATTGCAAGTGGTTTTATTGCTGATACAACGTCTTTACCTTTAATCGTGAGCAAT
TTGGTCAATATCATTTCTGCAGATTACTTTAACATTAGTTTCTCTCAATATCTTAGTAGAATGATTATCCCTAATTTATT
CTCGTTATTAGCTAGCCTTCTAGTTTTGTGGTTATATTTTAGAAAAGCGATTCCTAAATCATTTGATGCAAATCACATAA
AAAAACCTATAGATGCCATTAATGATTTAAAGCTATTTAAAATTTCATGGATTGTTCTAGTTATATTACTTTTCGGCTAT
CTAATCAGTGAATTTACTAAAATTCCGGTATCAATTTTCACCGGAATCATTGCTTTTATATTTCTAATATTGGCTCGTAA
ATCAAATGCTGTAAATATTAAGCAAGTCATTAAGGGCGCACCTTGGAATATAGTATTATTTTCAATTGGTATGTATATCG
TCGTATTCGGCTTAAGAAATGCTGGCATTACTTTAATATTAGCTAAAATATTAGAATATATTTCCAATTACGGTCTATTT
AGCACTATTTTGGGAATGGGCTTCATTTCAGCATTTTTATCATCAATAATGAATAATATGCCTACAGTTTTAATAGATGC
GATTGCTATTGGTCAATCAAATGTCCATGGCATGTTAAAAGAAGGCCTAATTTATGCAAATGTTATCGGTTCTGATTTAG
GTCCAAAAATTACACCGATAGGCTCTTTAGCTACATTACTGTGGTTACACGTCTTAACACAAAAAGATGTTAAGATTTCT
TGGGGCACATACTTTAAAACTGGTATCATCATTACAATTCCAGTACTATTTTTCACACTTTTAGGATTATATCTAACACT
TATACTATTTTAA

Protein sequence :
MMTTLATFIFLVTLLFVLWQPKGLDIGFTALAGAFIAVITGVVSFSDVFEVTGIVWNATLTFVSVILISLILDKVGLFEW
SAIHMLHASKGSGLKMFVYIILLGAVVAAFFANDGAALILTPIVLAMVKNIGFSKRAIFPFIIASGFIADTTSLPLIVSN
LVNIISADYFNISFSQYLSRMIIPNLFSLLASLLVLWLYFRKAIPKSFDANHIKKPIDAINDLKLFKISWIVLVILLFGY
LISEFTKIPVSIFTGIIAFIFLILARKSNAVNIKQVIKGAPWNIVLFSIGMYIVVFGLRNAGITLILAKILEYISNYGLF
STILGMGFISAFLSSIMNNMPTVLIDAIAIGQSNVHGMLKEGLIYANVIGSDLGPKITPIGSLATLLWLHVLTQKDVKIS
WGTYFKTGIIITIPVLFFTLLGLYLTLILF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 2e-136 81
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 8e-137 81
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 1e-143 81
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 2e-101 56

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB2 YP_041242.1 arsenical pump membrane protein 2 BAC0574 Protein 5e-139 81
arsB2 YP_041242.1 arsenical pump membrane protein 2 BAC0575 Protein 4e-144 81
arsB2 YP_041242.1 arsenical pump membrane protein 2 BAC0578 Protein 7e-103 56
arsB2 YP_041242.1 arsenical pump membrane protein 2 BAC0576 Protein 2e-101 56
arsB2 YP_041242.1 arsenical pump membrane protein 2 BAC0577 Protein 6e-101 55
arsB2 YP_041242.1 arsenical pump membrane protein 2 BAC0031 Protein 1e-97 55