|
Name : pyk (SAR1776) Accession : YP_041163.1 Strain : Staphylococcus aureus MRSA252 Genome accession: NC_002952 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : 2.7.1.40 Position : 1844896 - 1846653 bp Length : 1758 bp Strand : - Note : Similar to Bacillus licheniformis pyruvate kinase Pyk SW:KPYK_BACLI (P51181) (585 aa) fasta scores: E(): 2.9e-125, 62.28% id in 586 aa, and to Escherichia coli, and pyruvate kinase I PykF SW:KPY1_ECOLI (P14178) (470 aa) fasta scores: E(): 9.9e-72, 48.53% DNA sequence : ATGAGAAAAACTAAAATTGTATGTACAATTGGACCAGCTTCAGAATCAGAAGAAATGATTGAGAAATTAATCAATGCTGG TATGAACGTTGCACGATTAAACTTTTCACATGGTAGTCATGAAGAGCATAAAGGTAGAATTGATACAATTCGTAAAGTAG CTAAAAGATTAGACAAAATTGTAGCAATTTTATTAGATACGAAAGGTCCAGAAATTCGTACGCATAATATGAAAGACGGT ATCATTGAACTTGAACGTGGTAACGAAGTTATTGTTAGCATGAATGAAGTTGAAGGAACACCTGAAAAGTTCTCTGTAAC TTATGAAAACTTAATTAACGATGTTCAAGTAGGTTCATACATTTTACTTGATGATGGCTTAATTGAATTACAAGTTAAAG ATATTGACCATGCTAAAAAAGAAGTTAAATGTGATATTTTAAACTCTGGTGAGCTTAAAAACAAAAAAGGTGTTAACTTA CCTGGTGTAAGAGTTAGTTTACCTGGTATTACAGAAAAAGATGCTGAAGATATCCGTTTCGGTATTAAAGAAAATGTTGA CTTCATTGCAGCAAGTTTCGTACGTCGTCCTAGTGATGTTTTAGAAATTCGTGAAATTTTAGAAGAACAAAAAGCTAACA TTTCAGTATTCCCTAAAATTGAAAACCAAGAAGGTATTGATAATATTGAGGAAATTCTTGAAGTGTCTGATGGTTTAATG GTTGCACGTGGTGACATGGGTGTTGAAATCCCACCTGAAAAAGTACCAATGGTTCAAAAAGATTTAATCAGACAATGTAA CAAATTAGGTAAACCAGTTATTACAGCTACACAAATGTTAGATTCTATGCAACGTAACCCACGTGCTACACGTGCAGAAG CTAGTGACGTTGCCAACGCAATCTATGATGGTACAGATGCAGTAATGTTATCTGGTGAAACTGCTGCTGGTTTATATCCT GAAGAAGCTGTTAAAACAATGAGAAATATTGCTGTATCAGCTGAAGCAGCCCAAGATTACAAAAAGTTATTGTCAGATCG TACTAAATTAGTTGAAACTTCATTAGTGAATGCTATCGGTATTTCGGTTGCACATACAGCTTTAAACTTAAATGTTAAAG CAATTGTAGCTGCTACTGAAAGTGGTTCAACGGCACGTACTATCTCTAAATATCGTCCGCATTCAGACATTATTGCAGTG ACTCCAAGTGAAGAAACTGCACGTCAATGTTCAATTGTTTGGGGTGTTCAACCTGTAGTTAAAAAAGGACGTAAGAGTAC AGATGCATTGTTAAACAATGCAGTTGCAACAGCTGTTGAAACTGGTAGAGTAACTAATGGTGATTTAATCATTATTACTG CTGGTGTACCAACTGGTGAAACTGGAACTACTAATATGATGAAAATCCACCTAGTTGGTGACGAAATTGCTAATGGTCAA GGTATTGGACGTGGATCAGTTGTTGGTACTACGTTAGTTGCTGAAACTGTTAAAGATTTAGAAGGTAAAGATTTATCTGA CAAAGTTATCGTTACAAACTCAATCGATGAAACGTTTGTACCTTATGTAGAAAAAGCGTTAGGCTTAATTACAGAAGAAA ATGGAATTACATCACCAAGTGCAATTGTTGGTTTAGAAAAAGGTATTCCAACAGTTGTAGGTGTAGAAAAAGCTGTTAAA AACATAAGCAATAACGTGTTAGTTACGATTGATGCTGCTCAAGGTAAAATCTTTGAAGGATATGCAAACGTACTATAA Protein sequence : MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDG IIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNL PGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIEEILEVSDGLM VARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYP EEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAV TPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVTNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQ GIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVK NISNNVLVTIDAAQGKIFEGYANVL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 4e-94 | 49 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 3e-94 | 49 |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 3e-94 | 49 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 1e-93 | 49 |
| pykA | NP_273151.1 | pyruvate kinase | Not tested | IHT-A | Protein | 1e-57 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pyk | YP_041163.1 | pyruvate kinase | VFG0479 | Protein | 1e-94 | 49 |
