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Name : SAR0169 (SAR0169) Accession : YP_039634.1 Strain : Staphylococcus aureus MRSA252 Genome accession: NC_002952 Putative virulence/resistance : Virulence Product : aldehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : - Position : 186616 - 188103 bp Length : 1488 bp Strand : + Note : Similar to Vibrio cholerae aldehyde dehydrogenase AldA SW:DHAL_VIBCH (P23240) (506 aa) fasta scores: E(): 7.5e-81, 44.490% id in 490 aa, and to Alteromonas sp aldehyde dehydrogenase OlgA TR:O50609 (EMBL:AB009654) (505 aa) fasta scores: E(): 8.8e-78, 43.03 DNA sequence : ATGGCAGTAAACGTTCGAGATTATATAGCAGAGAATTATGGTTTATTTATCAATGGGGAATTTGTTAAAGGTAGCAGTGA CGAGACAATCGAAGTGACTAATCCAGCAACTGGAGAAACACTATCACATATTACAAGAGCAAAAGATAAAGATGTCGATC ATGCAGTCAAAGTGGCGCAAGAGGCATTTGAATCATGGTCATTAACTTCTAAATCAGAACGTGCACAAATGTTGCGTGAT ATTGGTGATAAATTAATGGCACAAAAAGATAAAATTGCAATGATTGAAACATTAAATAATGGTAAACCGATTCGTGAGAC AACAGCAATTGATATTCCATTTGCTGCAAGACATTTCCATTATTTCGCAAGTGTTATTGAAACAGAAGAAGGTACAGTGA ATGATATCGATAAAGACACAATGAGTATCGTACGACATGAGCCGATTGGCGTCGTAGGTGCTGTTGTTGCTTGGAACTTC CCAATGCTATTAGCTGCATGGAAGATTGCGCCAGCCATTGCTGCAGGTAATACAATTGTGATTCAACCTTCGTCTTCAAC ACCATTAAGTTTATTGGAAGTTGCTAAAATTTTCCAAGAGGTATTACCTAATGGTGTTGTCAATATACTAACGGGTAAAG GTTCAGAATCAGGTAATGCAATTTTCAATCATGATGGGGTAGATAAATTATCATTTACGGGCTCAACTGATGTAGGTTAT CAAGTTGCCGAAGCTGCAGCGAAACATCTAGTACCTGCTACTTTAGAGCTTGGTGGTAAAAGCGCCAATATCATATTAGA TGATGCTAATTTAGACCTTGCAGTTGAAGGTATTCAGTTAGGTATTTTATTCAACCAAGGTGAAGTATGTAGTGCAGGTT CTCGATTATTAGTTCATGAAAAAATTTATGATCAATTGGTGCCACGTTTACAAGAGGCATTTTCAAATATTAAAGTTGGA GATCCACAAGATGAAGCTACACAAATGGGTAGTCAAACTGGTAAGGATCAATTAGATAAAATTCAATCATATATTGATGC AGCAAAAGAATCAGATGCACAAATTTTAGCAGGTGGTCATCGTTTAACTGAAAATGGGTTAGATAAAGGATTCTTCTTTG AACCAACGTTAATTGCTGTGCCAGATAATCATCATAAATTAGCGCAAGAAGAAATATTTGGACCAGTTTTAACAGTGATT AAAGTGAAGGATGATCAAGAAGCAATTGATATAGCTAATGATTCAGAGTATGGTTTAGCTGGCGGCGTATTTTCTCAAAA TATCACACGTGCATTAAATATTGCTAAAGCTGTTCGTACAGGACGTATTTGGATTAACACTTACAACCAAGTACCAGAAG GCGCACCATTTGGTGGTTATAAAAAATCAGGTATCGGTCGAGAAACTTATAAAGGTGCGTTAAGTAACTATCAACAAGTT AAAAATATTTATATTGATACAAGCAATGCTTTAAAAGGTTTGTACTAG Protein sequence : MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQEAFESWSLTSKSERAQMLRD IGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNF PMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPNGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGY QVAEAAAKHLVPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVG DPQDEATQMGSQTGKDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEIFGPVLTVI KVKDDQEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQV KNIYIDTSNALKGLY |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 2e-97 | 45 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 5e-100 | 44 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 5e-100 | 44 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 5e-100 | 44 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 1e-99 | 44 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| SAR0169 | YP_039634.1 | aldehyde dehydrogenase | VFG0082 | Protein | 1e-97 | 45 |
