Gene Information

Name : hemC (SAR1750)
Accession : YP_041137.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1812668 - 1813594 bp
Length : 927 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGCGTAAATTAGTCGTTGGCTCCAGAAGAAGTAAATTAGCTTTAACACAAAGCCAGCAATTTATTGATAAATTAAAAGC
TGTCGAGCCAAATCTAGAAATTGAAATTAAAGAAATTGTCACGAAAGGCGATCGTATAGTAGATAAACAATTGTCTAAAG
TCGGAGGCAAAGGCTTATTTGTTAAAGAAATACAACATGAACTTTTTGAAAAAAATATCGATATGGCAATACACTCGCTG
AAAGACGTACCAAGTGTAATTCCGGAAGGTTTAACATTAGGTTGTATCCCTGATAGAGAATTACCTTTTGATGCGTATAT
TTCTAAAACACATACACCACTATCCCAATTGCCAGAAGGTAGTATTATTGGTACTAGTTCATTACGTCGTGGTGCACAAA
TATTATCTAAGTATCCTAATTTAGAGATTAAATGGATTAGAGGTAATATAGATACACGATTAGAAAAGTTACAAACTGAA
GATTATGATGCGATTATTTTAGCTGCAGCTGGTTTAAGAAGAATGGGCTGGTCAGATGATATTGTAACATCTTATCTTGA
TAGAGATACATTGTTACCTGCAATTGGACAAGGTGCTTTAGGGATAGAATGTCGTAGTGACGATGAAGAACTATTAACAT
TATTAAGCAAAGTACATAATGATGAGGTTGCAAAATGTGTGACTGCTGAACGAACGTTTTTAGCAGAAATGGATGGTAGT
TGTCAGGTGCCAATCGCAGGATATGCTACAATCTCAGATCAAAAAGAAATCGAATTTACAGGTTTAATTATGACCCCAGA
TGGTAAAGAACGATTTGAATATACAATGAACGGAACAGATCCGGTTGAGTTAGGAAAAAAAGTGAGTAACAAATTAAAAG
AGCAAGGTGCTTATGAAATTATAAAACGCTTAAATGAACAACATTAA

Protein sequence : 
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLFVKEIQHELFEKNIDMAIHSL
KDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEGSIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTE
DYDAIILAAAGLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEIIKRLNEQH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 7e-64 47
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 7e-64 47