Gene Information

Name : capD (SAR0154)
Accession : YP_039619.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Virulence
Product : capsular polysaccharide synthesis enzyme
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : -
Position : 170815 - 172638 bp
Length : 1824 bp
Strand : +
Note : Highly similar to Staphylococcus aureus capsular polysaccharide synthesis enzyme Cap5D TR:P95698 (EMBL:U81973) (607 aa) fasta scores: E(): 1.5e-214, 99.012% id in 607 aa, and to Staphylococcus aureus capsular polysaccharide synthesis enzyme Cap8D TR:P7237

DNA sequence :
ATGGCACATTTATCTGTGAAATTGCGGCTTTTAATACTAGCATTAATCGATTCACTGATAGTGACATTTTCAGTATTCGT
AAGTTATTACATTTTAGAACCGTATTTCAAAACATATTCTGTCAAATTATTAATATTGGCAGCTATATCACTATTCATAT
CGCATCATATTTCAGCATTTATTTTTAATATGTATCATCGAGCGTGGGAATATGCCAGTGTGAGTGAATTGATTTTAATT
GTTAAAGCTGTGACGACATCTATCGTTATTACGATGGTGTTCGTGACAATTGTTACAGGCAATAGACCGTTTTTTAGGTT
GTATTTAATTACATGGATGATGCACTTGATTTTAATAGGTGGCTCAAGGTTATTTTGGCGTATTTATCGGAAATACCTTG
GAGGTAAGTCATTTAATAAGAAGCCAACTTTAGTTGTTGGTGCTGGTCAAGCAGGTTCAATGCTGATTAGAAAAATGTTG
AAAAGTGACGAAATGAAACTTGAACCGGTATTAGCAGTCGATGATGACGAACATAAACGTAATATCACAATTACTGAGGG
TGTAAAAGTCCAAGGTAAAATCGCGGATATTCCAGAACTAGTGAGGAAATATAAGATTAAAAAAATTATCATTGCAATTC
CAACTATTGGTCAAGAGCGTTTGAAAGAAATTAATAATATTTGCCATATGGATGGCGTAGAGTTATTGAAAATGCCAAAT
ATAGAAGACGTCATGTCTGGTGAGTTAGAAGTGAACCAACTGAAAAAAGTTGAAGTAGAAGATTTACTTGGCAGAGATCC
TGTTGAATTAGATATGGATATGATATCAAATGAATTGACGAATAAAACTATTTTAGTTACGGGCGCTGGAGGTTCAATAG
GATCAGAAATTTGTAGACAAGTTTGTAATTTCTATCCAGAACGTATTATTCTACTTGGCCATGGTGAAAACAGTATTTAT
TTAATCAATCGTGAATTGCGAAATCGCTTCGGAAAAAATGTTGATATCGTTCCTATTATAGCGGATGTGCAAAATAGAGC
GCGTATGTTTGAAATTATGGAAATGTATAAACCATACGCAGTTTATCATGCAGCAGCACACAAGCACGTGCCGTTAATGG
AAGACAACCCTGAAGAAGCAGTACGTAATAATATTTTAGGTACGAAAAATACTGCTGAAGCTGCTAAAAATGCAGAGGTA
AAGAAATTCGTTATGATTTCTACGGATAAAGCCGTTAATCCACCTAATGTCATGGGAGCTTCAAAGCGAATTGCAGAAAT
GATTATTCAAAGTTTAAATGATGAAACGCATCGAACAAATTTTGTTGCAGTGAGATTTGGTAATGTACTTGGATCGAGAG
GATCTGTGATTCCACTTTTCAAAAGTCAAATTGAAGAAGGTGGGCCAGTTACTGTGACACATCCTGAAATGACACGTTAC
TTTATGACAATTCCTGAAGCTTCTAGACTAGTTTTGCAGGCAGGGGCATTAGCAGAAGGTGGCGAAGTATTTGTGTTAGA
TATGGGAGAACCAGTGAAAATAGTAGATTTAGCACGAAATTTAATTAAGTTAAGTGGTAAGAAAGAAGACGATATACGCA
TTACTTTTACAGGGATTAGACCTGGTGAAAAAATGTATGAAGAATTGATGAATAAGGATGAAATTCACCCTGAACAAGTA
TTTGAAAAAATTTATCGTGGCAAAGTACAACATATGAAATGTAATGAAGTTGAAGCGATTATTCAAGACATCGTCAATGA
CTTTAGTAAAGAAAAAATTATTAACTATGCCAATGGCAAAAAGGGAGATAATTATGTTCGATGA

Protein sequence :
MAHLSVKLRLLILALIDSLIVTFSVFVSYYILEPYFKTYSVKLLILAAISLFISHHISAFIFNMYHRAWEYASVSELILI
VKAVTTSIVITMVFVTIVTGNRPFFRLYLITWMMHLILIGGSRLFWRIYRKYLGGKSFNKKPTLVVGAGQAGSMLIRKML
KSDEMKLEPVLAVDDDEHKRNITITEGVKVQGKIADIPELVRKYKIKKIIIAIPTIGQERLKEINNICHMDGVELLKMPN
IEDVMSGELEVNQLKKVEVEDLLGRDPVELDMDMISNELTNKTILVTGAGGSIGSEICRQVCNFYPERIILLGHGENSIY
LINRELRNRFGKNVDIVPIIADVQNRARMFEIMEMYKPYAVYHAAAHKHVPLMEDNPEEAVRNNILGTKNTAEAAKNAEV
KKFVMISTDKAVNPPNVMGASKRIAEMIIQSLNDETHRTNFVAVRFGNVLGSRGSVIPLFKSQIEEGGPVTVTHPEMTRY
FMTIPEASRLVLQAGALAEGGEVFVLDMGEPVKIVDLARNLIKLSGKKEDDIRITFTGIRPGEKMYEELMNKDEIHPEQV
FEKIYRGKVQHMKCNEVEAIIQDIVNDFSKEKIINYANGKKGDNYVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 0.0 74
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 6e-178 71

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
capD YP_039619.1 capsular polysaccharide synthesis enzyme VFG1300 Protein 0.0 99