Gene Information

Name : malA (SAR1584)
Accession : YP_040981.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : alpha-D-1,4-glucosidase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0366
EC number : 3.2.1.20
Position : 1655144 - 1656793 bp
Length : 1650 bp
Strand : -
Note : Similar to Staphylococcus xylosus alpha-D-1,4-glucosidase MalA TR:Q60015 (EMBL:X78853) (549 aa) fasta scores: E(): 1.2e-181, 79.342% id in 547 aa, and to Bacillus halodurans exo-alpha-1,4-glucosidase BH3868 TR:Q9K664 (EMBL:AP001520) (553 aa) fasta scores:

DNA sequence :
ATGAATAAGCAATGGTGGAAAGAAGCAGTAGCATATCAAGTATATCCAAGAAGTTTTAATGATAGTAATCACGATGGTAT
TGGGGATTTACCTGGAATGATTGATAAATTGGACTACTTAAAAGATTTAGGTATCGATGTCATTTGGCTCAGTCCAATGT
TTAAATCACCTAATGATGATAATGGTTATGATATTAGTGACTACCAAGAGATTATGGATGAATTTGGAACGATGGAAGAC
TTTGATCGTTTATTAAAAGGTGTTCATGATAGAGGTATGAAGCTTATTTTAGATTTAGTTGTGAATCATACATCTGATGA
ACATCCTTGGTTTATAGAATCCAAATCTAGTAAAGACAATCCCAAACGTGATTGGTACATTTGGCAAGATCCAAAGCCAG
ATGGCTCTGAACCTAACAACTGGGAAAGTATATTTAATGGATCTACATGGGAATATGATGCTAATACTGAGCAATATTAT
TTCCATCTATTCAGTAAAAAACAACCTGATTTGAATTGGGGTAATCCGGAAGTTAGAGATGCTGTATTTGAAATGATGAA
CTGGTGGTTTGATAAAGGCATTGATGGATTTAGAGTAGATGCAATTACGCATATTAAGAAGACGTTTGAAGCGGGTGACT
TACCTGTACCTGAGGGTAAAACATATGCCCCAGCATTTGATGTAGATATGAATCAGCCAGGTATACAAACTTGGTTACAA
GAGATGAAAGATCGCTCATTAAGTAAGTATGACATTATGACTGTTGGTGAAGCGAATGGTGTAAGCCCTGATGATGCTGA
TGACTGGGTCGGGGAAGAAAATGGTAAATTTAATATGATATTCCAATTTGAACATTTGGGACTGTGGAATAGTGGTGATT
CTCACTTTGATGTAAATTCGTATAAGTCTGTATTAAATAGATGGCAAAAACAACTTGAAAATAAAGGTTGGAATGCGTTG
TTTATTGAAAATCATGACCAACCACGACGTGTATCGACGTGGGGTGACGATGACAAGTATTGGTATGAATCAGCAACAAG
TCATGCAGCAGTTTATTTCTTGCAACAAGGTACGCCATTCATTTATCAAGGTCAAGAAATTGGTATGACGAATTATCCAT
TTGAAAGTATTGAAACATTTAACGATGTTGCTGTTAAAAATGACTATCAAATTGTGAAAGCTCAAGGTGGAGATGTAGAC
GCTTTACTTGCGAAATATAAAGATGAGAACCGAGATAATTCTCGCACACCAATGCAATGGGATGATACGTTAAATGGAGG
ATTTACAAATGGTGAACCGTGGTTCCCAGTGAATCCGAATTATAAAACTATCAATGTTGCACAACAATTAGAAGATGAGG
ATTCAGTATTACAATTTTATAAAGATTTAATTCAATTAAGAAAGTCTAATGATGTATACGTATATGGTCAATTTGATTTA
GTAGATGCTGAAAATTCACAAGTTTTTGCGTACACGAGAACATTAAATGAAAAGCAAGTTCTTATTGTAGGTAATCTTAC
TAACCACGAAGCAGAATTAACTGTACCATTTGATATAAGTCATGGAGAAGTGAAGCTATTTAATTATGATGCCAAAGTTA
ATTTAAAACAGTTACTTCCATATGAAGCATGTGTTATCGAACTAAATTAA

Protein sequence :
MNKQWWKEAVAYQVYPRSFNDSNHDGIGDLPGMIDKLDYLKDLGIDVIWLSPMFKSPNDDNGYDISDYQEIMDEFGTMED
FDRLLKGVHDRGMKLILDLVVNHTSDEHPWFIESKSSKDNPKRDWYIWQDPKPDGSEPNNWESIFNGSTWEYDANTEQYY
FHLFSKKQPDLNWGNPEVRDAVFEMMNWWFDKGIDGFRVDAITHIKKTFEAGDLPVPEGKTYAPAFDVDMNQPGIQTWLQ
EMKDRSLSKYDIMTVGEANGVSPDDADDWVGEENGKFNMIFQFEHLGLWNSGDSHFDVNSYKSVLNRWQKQLENKGWNAL
FIENHDQPRRVSTWGDDDKYWYESATSHAAVYFLQQGTPFIYQGQEIGMTNYPFESIETFNDVAVKNDYQIVKAQGGDVD
ALLAKYKDENRDNSRTPMQWDDTLNGGFTNGEPWFPVNPNYKTINVAQQLEDEDSVLQFYKDLIQLRKSNDVYVYGQFDL
VDAENSQVFAYTRTLNEKQVLIVGNLTNHEAELTVPFDISHGEVKLFNYDAKVNLKQLLPYEACVIELN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
malL YP_251987.1 oligosaccharide alpha-1,6-glucosidase Not tested SCCmec Protein 3e-122 49