Gene Information

Name : SAR1541 (SAR1541)
Accession : YP_040943.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : DNA polymerase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 1625717 - 1627678 bp
Length : 1962 bp
Strand : -
Note : Similar to bacteriophage SP02 DNA polymerase L SW:DPOL_BPSP2 (P06225) (648 aa) fasta scores: E(): 6.5e-134, 54.103% id in 658 aa, and to the N-terminal region of bacteriophage APSE-1 probable DNA polymerase 45 SW:DPOL_BPAPS (Q9T1Q3) (993 aa) fasta scores:

DNA sequence :
TTGAGATTTATGAATATAGATATTGAAACATATAGCAGTAATGATATTTCGAAATGTGGTGCCTATAAATACACAGAAGC
TGAAGAATTCGAAATTTTAATTATAGCTTATTCAATAGATGGTGGAGCGATTAGTGCGATTGACATGACTAAAGTAGATA
ATGAGCCTTTCCACGCTGATTTTGAGACGTTTAAAATTGCTCTTTTTGATCCTGCTGTAAAAAAGTATGCATTCAATGCT
AATTTCGAAAGAACTTGTCTTGCTAAACATTTTAATAAACAGATGCCACCTGAAGAATGGATTTGCACAATGGTTAATTC
AATGCGTATTGGCTTACCTGCTTCGCTTGATAAAGTTGGAGAAGTTTTAAGACTACAAAACCAAAAAGATAAAGCAGGTA
AAAATTTAATTCGTTATTTCTCTATACCTTGTAAACCAACAAAAGTTAATGGAGGAAGAACAAGAAACTTGCCTGAACAT
GATCTTGAAAAATGGCAACAATTTATAGATTACTGTATTCGAGATGTAGAAGTAGAAATGACGATTGCTCATAAAATTAA
AGACTTTCCAGTAACTGCAATTGAACAAGCATATTGGGTTTTTGACCAACATATAAACGACAGAGGTATTAAGCTTTCTA
AATCATTGATGTTAGGAGCTAATGTGCTCGATAAGCAGAGTAAAGAAGAATTGCTTAATCAAGCTAAACATATAACAGGT
TTAGAAAATCCTAATAGTCCTACACAATTATTGGCTTGGTTAAAGAATGACCAAGGATTAGATATACCTAATTTACAAAA
GAAAACGGTTCAGGAGTACTTAAAAGAAGCAACAGGAAAAGCTAAAAAAATGCTAGAAATTAGATTGCAAATGTCTAAAA
CCAGTGTGAAAAAATACAACAAAATGCATGACATGATGTGCAGTGATGAACGGGTAAGAGGTCTGTTTCAATTTTACGGT
GCCGGTACTGGAAGATGGGCAGGTAGAGGTGTACAACTTCAGAATTTAACAAAGCATTATATTTCAGATACTGAATTAGA
AATAGCAAGAGATCTTATTAAAGAACAACGTTTTGACGATTTAGATTTATTACTCAATGTTCATCCTCAAGACTTATTAA
GTCAATTAGTTAGGACGACATTTACTGCTGAAGAAGGTAATGAACTAGCAGTAAGTGATTTTTCTGCAATAGAGGCAAGA
GTCATAGCATGGTATGCAAAAGAACAATGGCGTTTAGATGTGTTCAACACACACGGAAAGATATATGAAGCATCGGCTTC
TCAAATGTTTAATGTCCCGGTAGAAAGCATAACTAAAGGCGACCCTCTCAGACAAAAGGGAAAAGTGTCCGAATTAGCTT
TAGGTTATCAAGGTGGCGCTGGAGCTTTAAAAGCGATGGGTGCATTGGAAATGGGCATTGAAGAAAATGAATTACAAGGT
TTAGTTGATAGTTGGCGTAACGCAAATCCTAACATAGTTAATTTTTGGAAGGCTTGCCAAGAGGCTGCAATTAATACTGT
GAAATCCCGAAAGACGCATCATACGCATGGACTTAGATTTTATATGAAAAAAGGTTTTCTAATGATTGAACTGCCTAGTG
GAAGAGCTTTAGCTTATCCAAAAGCTTCAGTTGGTGAAAATAGTTGGGGTAGTCAAGTTGTTGAATTTATGGGCTTAGAT
CTTAACCGTAAATGGTCAAAGTTAAAAACGTATGGTGGGAAGTTAGTCGAGAATATTGTTCAAGCAACTGCAAGGGATTT
ACTTGCGATTTCTATAGCTAGGCTTGAAGCATCAGGTTTTAAAATAGTTGGACATGTCCATGATGAAGTAATTGTAGAAA
TACCTAGAGGTTCAAATGGACTTAAGGAAATCGAAACTATCATGAATAAGCCTGTCGATTGGGCAAAAGGATTGAATTTG
AATAGTGACGGATTTACTTCTCCGTTTTATATGAAGGATTAG

Protein sequence :
MRFMNIDIETYSSNDISKCGAYKYTEAEEFEILIIAYSIDGGAISAIDMTKVDNEPFHADFETFKIALFDPAVKKYAFNA
NFERTCLAKHFNKQMPPEEWICTMVNSMRIGLPASLDKVGEVLRLQNQKDKAGKNLIRYFSIPCKPTKVNGGRTRNLPEH
DLEKWQQFIDYCIRDVEVEMTIAHKIKDFPVTAIEQAYWVFDQHINDRGIKLSKSLMLGANVLDKQSKEELLNQAKHITG
LENPNSPTQLLAWLKNDQGLDIPNLQKKTVQEYLKEATGKAKKMLEIRLQMSKTSVKKYNKMHDMMCSDERVRGLFQFYG
AGTGRWAGRGVQLQNLTKHYISDTELEIARDLIKEQRFDDLDLLLNVHPQDLLSQLVRTTFTAEEGNELAVSDFSAIEAR
VIAWYAKEQWRLDVFNTHGKIYEASASQMFNVPVESITKGDPLRQKGKVSELALGYQGGAGALKAMGALEMGIEENELQG
LVDSWRNANPNIVNFWKACQEAAINTVKSRKTHHTHGLRFYMKKGFLMIELPSGRALAYPKASVGENSWGSQVVEFMGLD
LNRKWSKLKTYGGKLVENIVQATARDLLAISIARLEASGFKIVGHVHDEVIVEIPRGSNGLKEIETIMNKPVDWAKGLNL
NSDGFTSPFYMKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_494120.1 phage related DNA polymerase family A Not tested ¥ÕSa2 Protein 0.0 99
MW1425 NP_646242.1 DNA polymerase Not tested ¥ÕSa2 Protein 0.0 99
SEQ_2073 YP_002747288.1 phage DNA polymerase Not tested ¥ÕSeq4 Protein 3e-150 55