Gene Information

Name : SAR1141 (SAR1141)
Accession : YP_040554.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Virulence
Product : superantigen-like protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1186377 - 1187102 bp
Length : 726 bp
Strand : -
Note : these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation

DNA sequence :
ATGAAAAAGAACATCACGAACAAAATTGTTTTATCAACAGCATTGTTACTTTTAGGAACTACATCAACACAACCGCCTAA
AGCACCAATCAGTTTTTCATCTGAAGCAAAAGCATACAATATAAGTGAAAACGAAACGAATATCAATGAATTAATCAAAT
ATTACACGCAGCCACACCTTTCATTTTCTGGAAAATGGCTATGGCAAAACCCTAACGGTACCATACATGCAACATTACAA
ACGTGGGTTTGGTACACGCATATTCAAGTATTTGGTCCTGAAAGTTGGGGCAACATTAATCAATTAAGAGATAAATATGT
AGATATTTTTGGTACCAAGGATGAGGATACTATAGAAGGCTATTGGACTTATGATGAAACCTTTACTGGAGGTGTAACAC
CAGCAGCTACTTCATCTGATAAGCCTTATAAATTATTTTTAAAATATAAGGATAAACAACAAACTATGATTGGTGGACTT
GAGTTTTATCAAGGTAATAAACCAGTAATAACTTTAAAAGAACTAGATTTCCGCGTACGTCAAACTTTAATTAAGAACAA
AAAGCTATATAATGGAGAATTTAATAAAGGTCAAATTAGGATTACAGGTGGTGGTAATCATTATACGATTGATTTGAGTA
AAAAGTTAAAACTAACTGACACAAACAGTTATGTTAAAAATCCTCGACATGCAGAAATTGAAGTCATTCTTGAAAAATCT
CATTAG

Protein sequence :
MKKNITNKIVLSTALLLLGTTSTQPPKAPISFSSEAKAYNISENETNINELIKYYTQPHLSFSGKWLWQNPNGTIHATLQ
TWVWYTHIQVFGPESWGNINQLRDKYVDIFGTKDEDTIEGYWTYDETFTGGVTPAATSSDKPYKLFLKYKDKQQTMIGGL
EFYQGNKPVITLKELDFRVRQTLIKNKKLYNGEFNKGQIRITGGGNHYTIDLSKKLKLTDTNSYVKNPRHAEIEVILEKS
H

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAV1168 NP_371692.1 superantigen-like protein Virulence vSa¥ã Protein 4e-91 89
SA1011 NP_374284.1 superantigen-like protein Virulence vSa¥ã Protein 4e-91 89
MW1049 NP_645866.1 superantigen-like protein Not tested vSa¥ã Protein 2e-91 89
SACOL1180 YP_186043.1 superantigen-like protein Virulence vSa¥ã Protein 1e-91 89
SAUSA300_1061 YP_493759.1 superantigen-like protein Virulence vSa¥ã Protein 1e-91 89
SAKOR_01089 YP_008491277.1 Exotoxin Virulence vSa¥ã Protein 1e-91 89
SAKOR_01088 YP_008491276.1 Exotoxin Virulence vSa¥ã Protein 1e-68 69
SA1010 NP_374283.1 superantigen-like protein Virulence vSa¥ã Protein 9e-69 69
SACOL1179 YP_186042.1 superantigen-like protein Virulence vSa¥ã Protein 7e-69 69
MW1048 NP_645865.1 superantigen-like protein Virulence vSa¥ã Protein 7e-69 69
SAUSA300_1060 YP_493758.1 superantigen-like protein Virulence vSa¥ã Protein 7e-69 69
SAV1167 NP_371691.1 superantigen-like protein Virulence vSa¥ã Protein 6e-68 68
SACOL1178 YP_186041.1 superantigen-like protein Virulence vSa¥ã Protein 7e-60 63
SAUSA300_1059 YP_493757.1 superantigen-like protein Virulence vSa¥ã Protein 7e-60 63
SAKOR_01087 YP_008491275.1 Exotoxin Virulence vSa¥ã Protein 1e-59 63
MW1047 NP_645864.1 superantigen-like protein Virulence vSa¥ã Protein 1e-59 62
SAV1166 NP_371690.1 superantigen-like protein Virulence vSa¥ã Protein 8e-60 62
SA1009 NP_374282.1 superantigen-like protein Virulence vSa¥ã Protein 8e-60 62