Gene Information

Name : pdhD (SAR1070)
Accession : YP_040483.1
Strain : Staphylococcus aureus MRSA252
Genome accession: NC_002952
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 1116390 - 1117796 bp
Length : 1407 bp
Strand : +
Note : E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGGTAGTTGGAGATTTCCCAATTGAAACAGATACTATAGTAATCGGAGCAGGTCCTGGTGGATACGTTGCAGCAATTCG
TGCAGCTCAATTAGGACAAAAAGTAACAATCGTTGAGAAAGGTAATCTTGGTGGTGTTTGCTTAAACGTAGGATGTATTC
CTTCAAAAGCATTACTACATGCTTCTCACCGTTTTGTTGAAGCACAACATTCTGAAAACTTAGGTGTTATTGCTGAAAGT
GTTTCTTTAAACTTCCAAAAAGTTCAAGAATTCAAATCATCAGTTGTTAATAAATTAACTGGTGGTGTTGAAGGCTTACT
TAAAGGTAACAAAGTAAACATCGTTAAAGGTGAAGCATATTTCGTAGATAACAATAGCTTACGTGTTATGGACGAAAAGA
GCGCACAAACATACAACTTTAAAAACGCAATCATTGCAACAGGTTCAAGACCAATTGAAATTCCTAATTTCAAATTCGGT
AAACGTGTTATCGACTCAACAGGTGCTTTAAATTTACAAGAAGTACCAGGTAAATTAGTTGTAGTTGGTGGAGGATACAT
TGGATCAGAATTAGGTACAGCATTTGCTAACTTTGGTTCAGAAGTAACCATCCTTGAAGGTGCTAAAGATATCTTAGGTG
GCTTCGAAAAACAAATGACACAACCTGTTAAAAAAGGTATGAAAGAAAAAGGTGTTGAAATCGTTACTGAAGCAATGGCT
AAATCAGCTGAAGAAACAGATAACGGAGTTAAAGTTACTTATGAAGCTAAAGGCGAAGAGAAAACAATCGAAGCTGATTA
TGTATTAGTAACTGTAGGTCGTCGTCCAAACACAGACGAATTAGGCCTAGAAGAATTAGGTGTTAAATTCGCTGACCGTG
GATTATTAGAAGTTGATAAACAAAGCCGTACGTCTATCAGCAATATCTATGCAATTGGTGATATCGTTCCAGGTTTACCA
CTTGCTCACAAAGCTAGCTATGAAGCTAAAGTTGCTGCTGAAGCAATTGATGGTCAAGCTGCTGAAGTTGATTACATTGG
TATGCCAGCAGTATGCTTTACTGAACCTGAATTAGCTACAGTTGGTTATTCAGAAGCGCAAGCTAAAGAAGAAGGTTTAG
CAATTAAAGCTTCTAAATTTCCATATGCAGCAAATGGTCGTGCATTATCATTAGACGATACTAACGGATTTGTTAAACTT
ATTACACTTAAAGAAGATGATACTTTAATCGGTGCTCAAGTAGTTGGTACTGGTGCATCAGATATTATCTCTGAATTAGG
TTTAGCAATTGAAGCTGGTATGAATGCTGAAGATATCGCATTAACAATCCATGCACATCCAACATTAGGTGAGATGACTA
TGGAAGCAGCTGAAAAAGCTATCGGATACCCAATCCATACAATGTAA

Protein sequence :
MVVGDFPIETDTIVIGAGPGGYVAAIRAAQLGQKVTIVEKGNLGGVCLNVGCIPSKALLHASHRFVEAQHSENLGVIAES
VSLNFQKVQEFKSSVVNKLTGGVEGLLKGNKVNIVKGEAYFVDNNSLRVMDEKSAQTYNFKNAIIATGSRPIEIPNFKFG
KRVIDSTGALNLQEVPGKLVVVGGGYIGSELGTAFANFGSEVTILEGAKDILGGFEKQMTQPVKKGMKEKGVEIVTEAMA
KSAEETDNGVKVTYEAKGEEKTIEADYVLVTVGRRPNTDELGLEELGVKFADRGLLEVDKQSRTSISNIYAIGDIVPGLP
LAHKASYEAKVAAEAIDGQAAEVDYIGMPAVCFTEPELATVGYSEAQAKEEGLAIKASKFPYAANGRALSLDDTNGFVKL
ITLKEDDTLIGAQVVGTGASDIISELGLAIEAGMNAEDIALTIHAHPTLGEMTMEAAEKAIGYPIHTM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 6e-109 50