Gene Information

Name : SACOL0046 (SACOL0046)
Accession : YP_184956.1
Strain : Staphylococcus aureus COL
Genome accession: NC_002951
Putative virulence/resistance : Resistance
Product : metallo-beta-lactamase
Function : -
COG functional category : R : General function prediction only
COG ID : COG0491
EC number : -
Position : 53428 - 54756 bp
Length : 1329 bp
Strand : -
Note : identified by match to protein family HMM PF00581; match to protein family HMM PF00753

DNA sequence :
ATGTTTTTTAAACAATTTTATGATAAACATTTATCTCAAGCATCTTATTTAATCGGTTGTCAAAAAACTGGAGAAGCCAT
GATTATTGATCCTATTCGTGACTTATCTTCATATATTCGAGTTGCTGATGAAGAAGGTTTAACCATTACTCATGCAGCTG
AAACACATATACATGCAGATTTTGCTTCAGGAATTAGAGATGTTGCTATAAAGTTAAATGCTAATATTTATGTATCGGGT
GAAAGTGATGACACATTAGGTTATAAAAATATGCCTAACCACACTCATTTTGTTCAACATAATGACGATATTTATGTAGG
AAATATAAAATTAAAAGTGCTTCATACACCGGGTCACACGCCAGAAAGTATAAGTTTTTTACTTACTGACGAAGGTGCTG
GAGCACAAGTTCCAATGGGACTATTCAGTGGTGATTTTATTTTTGTAGGAGATATCGGTAGACCTGATTTACTAGAAAAA
GCGGTTAAAGTAGAAGGATCATCTGAAATAGGCGCTAAACAAATGTTTAAATCGATTGAAAGTATTAAAGACTTGCCAGA
TTACATTCAAATTTGGCCTGGCCATGGCGCTGGTAGTCCTTGTGGTAAATCTTTAGGTGCTATTCCAACATCTACTCTTG
GCTATGAAAAACAAACGAACTGGGCTTTTTCTGAAAATAACGAAGCTACCTTTATCGATAAACTCATTTCTGACCAACCT
GCACCACCACATCATTTTGCACAAATGAAAAAAATTAATCAATTCGGTATGAATTTATATCAACCTTATACGGTTTATCC
AGCTACAAATACAAACAGATTAACTTTTGATCTCCGCAGTAAGGAGGCTTATCATGGTGGACATATTGAAGGTACAATCA
ATATTCCATATGATAAAAATTTCATCAATCAAATTGGCTGGTATCTAAACTATGATCAAGAAATTAACTTGATTGGAGAC
TATCACCTTGTTTCAAAAGCAACACACACCTTACAACTCATTGGATACGATGATATTGCTGGATATCAATTACCGCAATC
TAAGATTCAAACACGTTCCATTCATAGTGAAGACATTACAGGTAACGAATCACATATATTAGATGTACGTAATGATAATG
AATGGAATAATGGCCACTTATCTCAAGCGGTTCATGTACCACACGGCAAACTTTTAGAAACAGATTTACCTTTCAATAAA
AACGATGTTATTTATGTACACTGTCAGTCTGGCATTAGAAGTTCGATAGCTATTGGTATTTTAGAACACAAAGGTTATCA
CAACATTATTAATGTAAATGAAGGTTATAAAGATATACAACTTTCTTAA

Protein sequence :
MFFKQFYDKHLSQASYLIGCQKTGEAMIIDPIRDLSSYIRVADEEGLTITHAAETHIHADFASGIRDVAIKLNANIYVSG
ESDDTLGYKNMPNHTHFVQHNDDIYVGNIKLKVLHTPGHTPESISFLLTDEGAGAQVPMGLFSGDFIFVGDIGRPDLLEK
AVKVEGSSEIGAKQMFKSIESIKDLPDYIQIWPGHGAGSPCGKSLGAIPTSTLGYEKQTNWAFSENNEATFIDKLISDQP
APPHHFAQMKKINQFGMNLYQPYTVYPATNTNRLTFDLRSKEAYHGGHIEGTINIPYDKNFINQIGWYLNYDQEINLIGD
YHLVSKATHTLQLIGYDDIAGYQLPQSKIQTRSIHSEDITGNESHILDVRNDNEWNNGHLSQAVHVPHGKLLETDLPFNK
NDVIYVHCQSGIRSSIAIGILEHKGYHNIINVNEGYKDIQLS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SACOL0046 YP_184956.1 metallo-beta-lactamase Not tested Type-I SCCmec Protein 0.0 100
unnamed BAA86645.1 hypothetical protein Not tested Type-I SCCmec Protein 0.0 100
unnamed BAB83478.1 - Not tested SCC 12263 Protein 0.0 98
unnamed BAC57482.1 hypothetical protein Not tested Type-IIIinv SCCmec Protein 1e-123 75
SAV0046 NP_370570.1 hypothetical protein Not tested Type-II SCCmec Protein 2e-123 75
SA0043 NP_373283.1 hypothetical protein Not tested Type-II SCCmec Protein 2e-123 75