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Name : splA (SACOL1869) Accession : YP_186697.1 Strain : Staphylococcus aureus COL Genome accession: NC_002951 Putative virulence/resistance : Virulence Product : serine protease SplA Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG3591 EC number : - Position : 1920785 - 1921501 bp Length : 717 bp Strand : - Note : identified by similarity to GP:9739156; match to protein family HMM PF00089 DNA sequence : ATGAATAAAAATGTAATGGTTAAAGGTTTAACTGCTTTAACTATTTTAACTATTTTAACATCTCTTGGTTTTGCTGAAAA TATTTCTAATCAGCCTCATTCAATTGCCAAAGCAGAAAAGAATGTCAAAGAAATTACCGATGCAACTAAGGAACCATACA ATTCAGTGGTAGCATTTGTGGGTGGTACTGGTGTAGTTGTTGGTAAAAATACAATCGTAACTAACAAACATATCGCTAAA AGTAATGATATTTTTAAAAATAGAGTATCAGCACATCATTCGAGTAAAGGTAAAGGCGGAGGAAACTACGACGTTAAAGA CATTGTAGAATATCCCGGAAAAGAAGACCTTGCGATAGTTCATGTTCATGAAACAAGTACAGAAGGTTTGAATTTTAATA AGAACGTTAGTTATACAAAATTTGCAGACGGAGCAAAAGTGAAAGATAGAATTTCTGTTATTGGTTATCCAAAGGGTGCA CAAACAAAATATAAAATGTTTGAATCGACAGGAACGATTAACCATATCAGTGGAACGTTTATGGAATTTGATGCGTATGC ACAACCAGGTAATTCAGGATCTCCTGTATTGAATTCTAAACATGAACTGATTGGTATTTTATATGCAGGTAGTGGAAAAG ATGAATCTGAAAAGAATTTCGGTGTTTATTTCACACCACAATTAAAAGAATTTATTCAAAATAATATTGAAAAATAA Protein sequence : MNKNVMVKGLTALTILTILTSLGFAENISNQPHSIAKAEKNVKEITDATKEPYNSVVAFVGGTGVVVGKNTIVTNKHIAK SNDIFKNRVSAHHSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFADGAKVKDRISVIGYPKGA QTKYKMFESTGTINHISGTFMEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| splA | YP_186697.1 | serine protease SplA | Virulence | vSa¥â | Protein | 3e-83 | 100 |
| splA | YP_001332740.1 | serine protease SplA | Virulence | vSa¥â | Protein | 3e-83 | 100 |
| splA | YP_494449.1 | serine protease SplA | Virulence | vSa¥â | Protein | 5e-82 | 99 |
| SAS1736 | YP_043852.1 | serine protease | Virulence | vSa¥â | Protein | 2e-81 | 99 |
| splA | NP_646572.1 | serine protease SplA | Virulence | vSa¥â | Protein | 2e-81 | 99 |
| SAKOR_01761 | YP_008491949.1 | Serine protease splA | Virulence | vSa¥â | Protein | 4e-81 | 97 |
| splA | NP_372337.1 | serine protease | Virulence | vSa¥â | Protein | 4e-80 | 96 |
| splA | NP_374920.1 | serine protease SplA | Virulence | vSa¥â | Protein | 4e-80 | 96 |
| splC | NP_374918.1 | serine protease SplC | Virulence | vSa¥â | Protein | 6e-37 | 50 |
| SAS1734 | YP_043850.1 | serine protease | Virulence | vSa¥â | Protein | 6e-37 | 50 |
| splC | YP_041284.1 | serine protease | Virulence | vSa¥â | Protein | 3e-37 | 50 |
| splC | YP_186695.1 | serine protease SplC | Virulence | vSa¥â | Protein | 1e-36 | 50 |
| splC | YP_001332738.1 | serine protease SplC | Virulence | vSa¥â | Protein | 1e-36 | 50 |
| splC | YP_494447.1 | serine protease SplC | Virulence | vSa¥â | Protein | 1e-36 | 50 |
| splC | NP_646570.1 | serine protease SplC | Virulence | vSa¥â | Protein | 7e-37 | 50 |
| splC | NP_372335.1 | serine protease | Virulence | vSa¥â | Protein | 6e-37 | 50 |
| SAKOR_01759 | YP_008491947.1 | Serine protease splC | Virulence | vSa¥â | Protein | 2e-36 | 50 |
| SAS1735 | YP_043851.1 | serine protease | Virulence | vSa¥â | Protein | 2e-33 | 48 |
| splB | NP_646571.1 | serine protease SplB | Virulence | vSa¥â | Protein | 2e-33 | 48 |
| splB | YP_186696.1 | serine protease SplB | Virulence | vSa¥â | Protein | 3e-33 | 48 |
| splB | YP_001332739.1 | serine protease SplB | Virulence | vSa¥â | Protein | 3e-33 | 48 |
| splB | YP_494448.1 | serine protease SplB | Virulence | vSa¥â | Protein | 3e-33 | 48 |
| splB | NP_372336.1 | serine protease | Virulence | vSa¥â | Protein | 2e-33 | 48 |
| splB | NP_374919.1 | serine protease SplB | Virulence | vSa¥â | Protein | 2e-33 | 48 |
| SAKOR_01760 | YP_008491948.1 | Serine protease splB | Virulence | vSa¥â | Protein | 2e-33 | 48 |
| SAS1733 | YP_043849.1 | serine protease | Virulence | vSa¥â | Protein | 1e-29 | 45 |
| splF | NP_646569.1 | serine protease SplF | Virulence | vSa¥â | Protein | 1e-29 | 45 |
| splF | YP_494444.1 | serine protease SplF | Virulence | vSa¥â | Protein | 3e-29 | 45 |
| SACOL1864 | YP_186692.1 | serine protease SplF | Virulence | vSa¥â | Protein | 3e-29 | 45 |
| splF | YP_001332735.1 | serine protease SplF | Virulence | vSa¥â | Protein | 3e-29 | 45 |
| splF | NP_372333.1 | serine protease | Virulence | vSa¥â | Protein | 3e-29 | 45 |
| splF | NP_374916.1 | serine protease SplF | Virulence | vSa¥â | Protein | 3e-29 | 45 |
| splD | YP_001332737.1 | serine protease SplD | Virulence | vSa¥â | Protein | 6e-28 | 44 |
| splD | YP_494446.1 | serine protease SplD | Virulence | vSa¥â | Protein | 6e-28 | 44 |
| SACOL1866 | YP_186694.1 | serine protease SplD | Virulence | vSa¥â | Protein | 5e-28 | 44 |
| splD | NP_372334.1 | serine protease | Virulence | vSa¥â | Protein | 6e-28 | 44 |
| splD | NP_374917.1 | serine protease SplD | Virulence | vSa¥â | Protein | 6e-28 | 44 |
| SACOL1865 | YP_186693.1 | serine protease SplE | Virulence | vSa¥â | Protein | 6e-27 | 44 |
| splE | YP_001332736.1 | serine protease SplE | Virulence | vSa¥â | Protein | 6e-27 | 44 |
| splE | YP_494445.1 | serine protease SplE | Virulence | vSa¥â | Protein | 6e-27 | 44 |
| splE | YP_041282.1 | serine protease | Virulence | vSa¥â | Protein | 1e-27 | 44 |
| SAKOR_01758 | YP_008491946.1 | Serine protease splD | Virulence | vSa¥â | Protein | 6e-28 | 44 |
| SAR1905 | YP_041283.1 | serine protease | Virulence | vSa¥â | Protein | 8e-26 | 42 |
