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Name : leuS (PG0796) Accession : NP_905058.1 Strain : Porphyromonas gingivalis W83 Genome accession: NC_002950 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 849763 - 852540 bp Length : 2778 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGGAATATAACTTTCAGGAAATAGAAAAGCGTGTGCAGGGACAGTGGCGCAAAGACAAGGTTTACCGCGTTGCGGAAGA CACAAGTAAAAAACCTTTCTACGTGCTCGACATGTTTCCGTATCCTTCCGGAGCAGGACTGCATGTAGGGCATCCACTTG GTTATATAGCTTCCGATATTTTTTCGCGCTATAAGCGTTTGCGTGGATTCAATGTATTGCATCCGATGGGATATGATGCA TTCGGCCTACCTGCCGAACAATATGCCATCCAAACCGGCCAACACCCCGAAAAAACAACAGAAGAAAATACAGCTCGCTA TCGCGAGCAACTGGACAAAATCGGCTTTTCGTACGATTGGGAACGCGAGATTCGCACTTGTGATCCGAATTATTATAAAT GGACACAGTGGGCTTTCCTGAAAATGTTCGACTCGTACTACTGCAATCAAGCACAACAGGCACGACCGATAAGCGAGCTG ATCGAAGTTTTTGCCCGACAAGGTAATGATGGTCTCAATGTGGCATGCGGCGAAGGAGTCCGTTTCACGGCGGAGGAGTG GACAGCCATGAGCGAAAAAGAACAACAAGAGATACTCATGAATTACCGTCTGGCTTATTTGGGCGACACGATGGTCAATT GGTGTCCGGCCCTCGGTACCGTATTAGCTAACGATGAAGTCAAGGACGGAGTGAGCGAACGTGGAGGACACCCCGTGGAG CAAAAGAAGATGCGCCAATGGTGCCTGCGCGTATCGGCCTATGCCGAGCGTTTGCTGCACGACCTTGAAACACTGGATTG GACTGAATCGTTGAAAGAGACACAGCGCAACTGGATCGGACGATCCGAAGGAGCCGAAATGGAGTTTCGTCTGGCCGGTA AGGATTGCACATTTACGATTTTTACTACCAGAGCCGACACGATATTCGGTGTCACGTTTATGGTATTGGCTCCTGAGAGC GAATTGGTTGAAGAGGTAACGACAGAGGAGCAGCGCGCTGCAGTGGAGACTTATCTGACAGAAACAAAGCGACGGACAGA ACGTGAACGAATATCCGACAAACGAGTCTCAGGAGTTTTCTCCGGCAGTTATGCCATCAATCCTCTCACCGGTAAGGAAA TTCCTATTTGGATCAGCGACTACGTATTGGCAGGATATGGCACAGGTGCTATTATGGCTGTGCCGGCTCATGATACGCGC GACTTTGCCTTTGCACGTCATTTCGATCTTCCCATCGTCCAAGTCGTCGTACCCGAGGGCGAACCGGCTACCGATCCTGC CACATGGGAGGATGCCAAAGACAGTAAGAGCGGTATAATGGTCAATTCCGATTTTCTGAATGGTCTCTCCGTAGAAGATG CCATAGCCCAAACCAAGGAGTATATCAGAGAAAAACACTTAGGTTGCGTGAAAGTAAACTACCGCCTGCGCGATGCTATT TTCAGTCGTCAGCGTTATTGGGGGGAACCTTTCCCCATCTACTACAAGGAGGGTATGCCTCACGCGCTGGATGAAGATCG ACTGCCGCTCCGATTGCCGGAGGTAGATAAATTCCTCCCCACAGAAAGCGGTGAACCGCCCCTTGGAAGAGCTACCGGCT GGCATACAGCCGAAGGTTATCCATACGAATTGAGCACAATGCCCGGATTTGCCGGTAGCAGTGCTTACTATCTGCGATAT ATGGATCCACAAAACGATACTGCACTCGTCAGCCGATCGGCGAATGAATATTGGCGTCACGTCGATCTATACATCGGTGG TACGGAGCACGCCACAGGACACCTGATTTATAGCCGCTTTTGGAACAAATTTCTCTTCGACCTTGGTATCGTATGCGAAG CCGAACCTTTCCGCAAGCTGGTGAATCAGGGAATGATCCAAGGACGCTCCAACTTCGTCTATCGAATCAAGAATACCAAT ACATTCGTCAGCTATGGACTGCGCGAGCAATATGAGGTGACTCCACTCCATGTAGATGTCAATATCGTATCGAACGATCA GCTCGACATAGACCGCTTCCGTGCATGGCGTCCGGAGTACACTTCTGCAGAGTTCATCCTTGAAGATGGCAAGTATATCT GTGGATGGGCTATTGAGAAGATGAGCAAATCGATGTTTAACGTCGTCAATCCCGATGATATTATTGCTCGTTATGGAGCC GATACCCTGCGACTCTACGAAATGTTCCTCGGGCCGCTGGAGCAGAGCAAGCCTTGGGATACGAATGGTATCGATGGTGT ACACCGCTTTTTGAAAAAGTTCTGGGCGTTGTACTACAATACAGATGGTATACGCGTCACCGATACAGCACCGACAAAAG AGGAGCTGAAGAGCTTGCACAAGCTCATCAAAAAGGTAGGACAGGATATTGAATCTTTTTCTTTCAACACTTCAATACCC GCCTTCATGATTTGTGTGAATGAGCTGACAGCGGCCAAAACCACTTCTCGTGCCATACTATGTCCATTGCTGACAGTGCT CTCTCCTTTTGCACCGCATATCACCGAGTGGCTATGGCAGGAACTGGGAGTAGAAGGCAGTATCGTAACTGCAACTTGGC CCGAATACAATGAAGAGTATCTGGTGGAGAGCTGTGTACGCTATCCGGTGAGCTTCAATGGCAAGGTTCGTTTCAATATC GAACTGCCGGCCGATATGAGCAAAGAAGATGTAGAGCAAGCAGCCCTTATTGCTCCCGAAGCAGCCCGTTGGCTCGAAGG CAAGAGTCCGAAAAAAGTCATTGTAGTCCCCGGGAGGATCGTCAATGTAGTTGTATGA Protein sequence : MEYNFQEIEKRVQGQWRKDKVYRVAEDTSKKPFYVLDMFPYPSGAGLHVGHPLGYIASDIFSRYKRLRGFNVLHPMGYDA FGLPAEQYAIQTGQHPEKTTEENTARYREQLDKIGFSYDWEREIRTCDPNYYKWTQWAFLKMFDSYYCNQAQQARPISEL IEVFARQGNDGLNVACGEGVRFTAEEWTAMSEKEQQEILMNYRLAYLGDTMVNWCPALGTVLANDEVKDGVSERGGHPVE QKKMRQWCLRVSAYAERLLHDLETLDWTESLKETQRNWIGRSEGAEMEFRLAGKDCTFTIFTTRADTIFGVTFMVLAPES ELVEEVTTEEQRAAVETYLTETKRRTERERISDKRVSGVFSGSYAINPLTGKEIPIWISDYVLAGYGTGAIMAVPAHDTR DFAFARHFDLPIVQVVVPEGEPATDPATWEDAKDSKSGIMVNSDFLNGLSVEDAIAQTKEYIREKHLGCVKVNYRLRDAI FSRQRYWGEPFPIYYKEGMPHALDEDRLPLRLPEVDKFLPTESGEPPLGRATGWHTAEGYPYELSTMPGFAGSSAYYLRY MDPQNDTALVSRSANEYWRHVDLYIGGTEHATGHLIYSRFWNKFLFDLGIVCEAEPFRKLVNQGMIQGRSNFVYRIKNTN TFVSYGLREQYEVTPLHVDVNIVSNDQLDIDRFRAWRPEYTSAEFILEDGKYICGWAIEKMSKSMFNVVNPDDIIARYGA DTLRLYEMFLGPLEQSKPWDTNGIDGVHRFLKKFWALYYNTDGIRVTDTAPTKEELKSLHKLIKKVGQDIESFSFNTSIP AFMICVNELTAAKTTSRAILCPLLTVLSPFAPHITEWLWQELGVEGSIVTATWPEYNEEYLVESCVRYPVSFNGKVRFNI ELPADMSKEDVEQAALIAPEAARWLEGKSPKKVIVVPGRIVNVVV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 3e-119 | 43 |
